Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Miriam Tosetto"'
Autor:
Vanessa Zaiatz-Bittencourt, Fiona Jones, Miriam Tosetto, Caitriona Scaife, Gerard Cagney, Evan Jones, Glen A. Doherty, Elizabeth J. Ryan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The gut microbiota regulates chronic inflammation and has been implicated in the pathogenesis of a broad spectrum of disease including autoimmunity and cancer. Microbial short-chain fatty acids (SCFAs) e.g., butyrate have demonstrated immuno
Externí odkaz:
https://doaj.org/article/7ea9284ffa394ea0a9f11c4623309226
Autor:
Hannah K. Fitzgerald, Sinead A. O’Rourke, Eva Desmond, Nuno G. B. Neto, Michael G. Monaghan, Miriam Tosetto, Jayne Doherty, Elizabeth J. Ryan, Glen A. Doherty, Derek P. Nolan, Jean M. Fletcher, Aisling Dunne
Publikováno v:
Antioxidants, Vol 11, Iss 1, p 164 (2022)
The extracellular parasite and causative agent of African sleeping sickness Trypanosoma brucei (T. brucei) has evolved a number of strategies to avoid immune detection in the host. One recently described mechanism involves the conversion of host-deri
Externí odkaz:
https://doaj.org/article/daea71fc4daf47e5b167422d9b5c9366
Autor:
Adriana J Michielsen, Andrew E Hogan, Joseph Marry, Miriam Tosetto, Fionnuala Cox, John M Hyland, Kieran D Sheahan, Diarmuid P O'Donoghue, Hugh E Mulcahy, Elizabeth J Ryan, Jacintha N O'Sullivan
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27944 (2011)
Inflammatory mediators in the tumour microenvironment promote tumour growth, vascular development and enable evasion of anti-tumour immune responses, by disabling infiltrating dendritic cells. However, the constituents of the tumour microenvironment
Externí odkaz:
https://doaj.org/article/1fa55522fd5248f3ba6a2700a7b5a095
Autor:
Jayne Doherty, Neil O Morain, Roisin Stack, Miriam Tosetto, Rosanna Inzitiari, Sophie O Reilly, Lili Gu, Juliette Sheridan, Garret Cullen, Edel Mc Dermott, Maire Buckley, Gareth Horgan, Hugh Mulcahy, Margaret Walshe, Elizabeth J Ryan, Virginie Gautier, John Prostko, Edwin Frias, David Daghfal, Peter Doran, Colm O Morain, Glen A Doherty
Publikováno v:
Journal of Crohn's and Colitis.
Background and Aims Patients with inflammatory bowel disease [IBD] have an attenuated response to initial COVID-19 vaccination. We sought to characterize the impact of IBD and its treatment on responses after the third vaccine against SARS-CoV-2. Met
Publikováno v:
Journal of Crohn's & Colitis
Background and Aims Inflammatory bowel diseases [IBD], comprising Crohn’s disease [CD] and ulcerative colitis [UC], are chronic conditions characterized by severe dysregulation of innate and adaptive immunity resulting in the destruction of the int
Autor:
Jayne Doherty, Neil O Morain, Roisin Stack, Parker Girod, Miriam Tosetto, Rosanna Inzitiari, Juliette Sheridan, Garret Cullen, Edel McDermott, Maire Buckley, Gareth Horgan, Hugh Mulcahy, Elizabeth J Ryan, David Daghfal, Peter Doran, Colm O Morain, Glen A Doherty
Background and Aims Evidence suggests patients with inflammatory bowel disease [IBD] receiving TNF antagonists have attenuated response to vaccination against COVID-19. We sought to determine the impact of IBD and of various medications for treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18929521e9c6e0d9cd385a6f2c79fec9
Autor:
Robert Geraghty, Aoife Maguire, Cara Dunne, Kieran Sheahan, Petra Martin, David Fennelly, Miriam Tosetto, James J. Phelan, Elizabeth J. Ryan, Jacintha O'Sullivan, Adriana J. Michielsen, Sinead Noonan, Margaret R. Dunne
Publikováno v:
Cancer Immunology, Immunotherapy
HLA-DR, an MHC class II molecule that mediates antigen presentation, is a favourable prognostic indicator in colorectal cancer (CRC). However, the dynamics and location of HLA-DR expression during CRC development are unclear. We aimed to define HLA-D
Autor:
Jayne Doherty, Roisin Stack, Neil O'Morain, Parker Girod, Miriam Tosetto, Rosanna Inzitari, Juliette Sheridan, Garret Cullen, Maire Buckley, Hugh E. Mulcahy, Elizabeth J. Ryan, David J Daghfal, Peter Doran, Colm A. O'Morain, Glen Doherty
Publikováno v:
Gastroenterology. 162:S-599
Autor:
Simon J Furney, Elizabeth J. Ryan, Kieran Sheahan, Desmond C. Winter, Robert Geraghty, Miriam Tosetto, Valentina Thomas, Maura Cotter, Yi Ling Khaw
Publikováno v:
NPJ Genomic Medicine
npj Genomic Medicine, Vol 5, Iss 1, Pp 1-9 (2020)
npj Genomic Medicine, Vol 5, Iss 1, Pp 1-9 (2020)
Synchronous colorectal cancers (syCRCs) are two or more primary tumours identified simultaneously in a patient. Previous studies report high inter-tumour heterogeneity between syCRCs, suggesting independent origin and different treatment response, ma
Autor:
Francesco Caiazza, James J. Phelan, Laura Breen, Robert Power, Charles S. Craik, Petra Martin, Jacintha O'Sullivan, Kieran Sheahan, Elizabeth J. Ryan, Kate E. Killick, David Fennelly, Blathnaid Nolan, Simon J Furney, Glen A. Doherty, Miriam Tosetto, Fiona O'Neill, Katarzyna Oficjalska, Sinead Noonan
Publikováno v:
The American journal of pathology, vol 189, iss 10
Am J Pathol
Am J Pathol
Background & Aims: KH-type splicing regulatory protein (KHSRP) is a multifunctional nucleic acid binding protein. KHSRP regulates transcription, mRNA decay and translation, and miRNA biogenesis. These distinct functions are associated with key aspect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7c873cea34e7ebed9dad56a3dedc58d
https://escholarship.org/uc/item/3kp436t3
https://escholarship.org/uc/item/3kp436t3