Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Miriam Sutovsky"'
Autor:
Eriklis Nogueira, Filip Tirpák, Lauren E. Hamilton, Michal Zigo, Karl Kerns, Miriam Sutovsky, JaeWoo Kim, Dietrich Volkmann, Luca Jovine, Jeremy F. Taylor, Robert D. Schnabel, Peter Sutovsky
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
This study is part of a concerted effort to identify and phenotype rare, deleterious mutations that adversely affect sperm quality, or convey high developmental and fertility potential to embryos and ensuing progeny. A rare, homozygous mutation in EM
Externí odkaz:
https://doaj.org/article/fc990fac3292487aa7065b91da7cb39c
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
During sperm capacitation physiological changes occur that are required for fertilization. Here, the authors describe four sperm zinc signatures during invitro capacitation that are indicative of sperm quality and capacity to fertilize.
Externí odkaz:
https://doaj.org/article/333fbf48568c4cff80edcf29cbc61e1a
Autor:
Won-Hee Song, Dalen Zuidema, Young-Joo Yi, Michal Zigo, Zhibing Zhang, Miriam Sutovsky, Peter Sutovsky
Publikováno v:
Cells, Vol 10, Iss 9, p 2450 (2021)
Propagation of paternal sperm-contributed mitochondrial genes, resulting in heteroplasmy, is seldom observed in mammals due to post-fertilization degradation of sperm mitochondria, referred to as sperm mitophagy. Whole organelle sperm mitochondrion d
Externí odkaz:
https://doaj.org/article/d25f0e523ca140949db3b1d9c5040078
Autor:
Katerina Adamkova, Young-Joo Yi, Jaroslav Petr, Tereza Zalmanova, Kristyna Hoskova, Pavla Jelinkova, Jiri Moravec, Milena Kralickova, Miriam Sutovsky, Peter Sutovsky, Jan Nevoral
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 8, Iss 1, Pp 1-12 (2017)
Abstract Background The histone code is an established epigenetic regulator of early embryonic development in mammals. The lysine residue K9 of histone H3 (H3K9) is a prime target of SIRT1, a member of NAD+-dependent histone deacetylase family of enz
Externí odkaz:
https://doaj.org/article/39d40745037141fa85dc2ee1d55ed603
Publikováno v:
Biology Open, Vol 7, Iss 10 (2018)
Ubiquitin A-52 residue ribosomal protein fusion product 1 (Uba52), a ubiquitin-ribosomal fusion gene, is a major source of ubiquitin protein for covalent modification of proteinaceous substrates recycled by ubiquitin-proteasome system (UPS). Its role
Externí odkaz:
https://doaj.org/article/1f3d19c8d3e742aaaa5d1b7fb43fd47b
Autor:
Karl Kerns, Momal Sharif, Michal Zigo, Wei Xu, Lauren E. Hamilton, Miriam Sutovsky, Mark Ellersieck, Erma Z. Drobnis, Nicolai Bovin, Richard Oko, David Miller, Peter Sutovsky
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2121 (2020)
Building on our recent discovery of the zinc signature phenomenon present in boar, bull, and human spermatozoa, we have further characterized the role of zinc ions in the spermatozoa’s pathway to fertilization. In boar, the zinc signature differed
Externí odkaz:
https://doaj.org/article/212cb55f398045f1b14176eeba4cfb28
Autor:
Clayton Buckman, Christophe Ozanon, Jing Qiu, Miriam Sutovsky, Joyce Ann Carafa, Vanesa Y Rawe, Gaurishankar Manandhar, Antonio Miranda-Vizuete, Peter Sutovsky
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e61000 (2013)
Spermatid specific thioredoxin-3 (SPTRX3 or TXNDC8) is a testis/male germ line specific member of thioredoxin family that accumulates in the superfluous cytoplasm of defective human spermatozoa. We hypothesized that semen levels of SPTRX3 are reflect
Externí odkaz:
https://doaj.org/article/7cdefee1e21b42cab2ae7e9abde624bb
Autor:
Clayton Buckman, Christophe Ozanon, Jing Qiu, Miriam Sutovsky, Joyce Ann Carafa, Vanesa Y. Rawe, Gaurishankar Manandhar, Antonio Miranda-Vizuete, Peter Sutovsky
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/5ef2f5d8a74a479596e0ca719acef168
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34524 (2012)
Inorganic pyrophosphate (PPi) is generated by ATP hydrolysis in the cells and also present in extracellular matrix, cartilage and bodily fluids. Fueling an alternative pathway for energy production in cells, PPi is hydrolyzed by inorganic pyrophospha
Externí odkaz:
https://doaj.org/article/6cecce91cb9044c1b82c3b6b5f5270f3
Autor:
Shawn W Zimmerman, Gaurishankar Manandhar, Young-Joo Yi, Satish K Gupta, Miriam Sutovsky, John F Odhiambo, Michael D Powell, David J Miller, Peter Sutovsky
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17256 (2011)
Despite decades of research, the mechanism by which the fertilizing spermatozoon penetrates the mammalian vitelline membrane, the zona pellucida (ZP) remains one of the unexplained fundamental events of human/mammalian development. Evidence has been
Externí odkaz:
https://doaj.org/article/bd5c711321544820abb02ee4210a4153