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pro vyhledávání: '"Miriam Sharpe"'
Publikováno v:
Drugs. 62:1503-1538
Esomeprazole (S-isomer of omeprazole), the first single optical isomer proton pump inhibitor, generally provides better acid control than current racemic proton pump inhibitors and has a favourable pharmacokinetic profile relative to omeprazole. In a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87363c98f5cdc74d4822f2fc528ddbb3
https://doi.org/10.2165/00003495-200262100-00006
https://doi.org/10.2165/00003495-200262100-00006
Autor:
Miriam Sharpe, Blair Jarvis
Publikováno v:
Scopus-Elsevier
Mometasone furoate is a corticosteroid with relatively high in vitro potency. Recent randomised, double-blind, multicentre trials have assessed the efficacy of mometasone furoate delivered by dry powder inhaler over 12 weeks in adults and adolescents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dcfd3a4f522524fef7b80c0c1518081
https://doi.org/10.2165/00003495-200161090-00011
https://doi.org/10.2165/00003495-200161090-00011
Autor:
Raphaël Margueron, William J. Drury, William R. Taylor, Jinsook Son, Valeria De Marco, Philipp Voigt, Miriam Sharpe, Steven J. Gamblin, Stephen R. Martin, Vincenzo Pirrotta, Danny Reinberg, Katsuhito Ohno, Neil Justin
Polycomb group proteins have an essential role in the epigenetic maintenance of repressive chromatin states. The gene-silencing activity of the Polycomb repressive complex 2 (PRC2) depends on its ability to trimethylate lysine 27 of histone H3 (H3K27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ad0f25addd7f7ee46464cb373c06ff
https://europepmc.org/articles/PMC3772642/
https://europepmc.org/articles/PMC3772642/
Publikováno v:
Drugs. 62(14)
Polyethylene glycol (PEG)-liposomal doxorubicin is a formulation of the anthracycline doxorubicin in which the drug is encapsulated in PEG-coated liposomes. This alters the pharmacokinetic properties of doxorubicin, prolonging circulation time and en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84e96fcac014ee8a8d5c601560c76533
https://pubmed.ncbi.nlm.nih.gov/12269857
https://pubmed.ncbi.nlm.nih.gov/12269857
Publikováno v:
Drugs. 62(7)
Esomeprazole, the S-isomer of omeprazole, is the first proton pump inhibitor to be developed as a single optical isomer. It provides better acid control than current racemic proton pump inhibitors and has a favourable pharmacokinetic profile relative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e06ed79d51cd087949ff36c53bce24
https://pubmed.ncbi.nlm.nih.gov/11985491
https://pubmed.ncbi.nlm.nih.gov/11985491
Publikováno v:
Scopus-Elsevier
UNLABELLED Alendronate (alendronic acid) is a nitrogen-containing bisphosphonate which binds to bone surfaces and inhibits bone resorption by osteoclasts. Oral alendronate 5 or 10 mg/day produces sustained increases in bone mineral density (BMD) in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b59409e2d9954be968ca4694b67e5b9
https://pubmed.ncbi.nlm.nih.gov/11434454
https://pubmed.ncbi.nlm.nih.gov/11434454
Publikováno v:
Scopus-Elsevier
UNLABELLED Telmisartan is an angiotensin II receptor antagonist that is highly selective for type 1 angiotensin II receptors. It was significantly more effective than placebo in large (n >100), double-blind, randomised, multicentre clinical trials in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::798abe975f9b3fd0db6b914c2e7f5b63
http://www.scopus.com/inward/record.url?eid=2-s2.0-0034874986&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0034874986&partnerID=MN8TOARS
Publikováno v:
Scopus-Elsevier
The prodrug fenofibrate, a synthetic phenoxy-isobutyric acid derivative, is rapidly hydrolyzed in vivo to form fenofibric acid, which alters plasma lipid levels by activating the peroxisome proliferator-activated receptor alpha. The micronized fenofi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f23cae38330d71eb8ff92d3aec6d737
http://www.scopus.com/inward/record.url?eid=2-s2.0-0036259543&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0036259543&partnerID=MN8TOARS
Publikováno v:
Scopus-Elsevier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::17a19471eda1a59c8462528b820a1bdb
http://www.scopus.com/inward/record.url?eid=2-s2.0-0036096454&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0036096454&partnerID=MN8TOARS