R-Ras1 and R-Ras2 Expression in Anatomical Regions and Cell Types of the Central Nervous System

Autor: Gonzalo Garcia-Martin, Miriam Sanz-Rodriguez, Berta Alcover-Sanchez, Marta P. Pereira, Francisco Wandosell, Beatriz Cubelos

Publikováno v: International Journal of Molecular Sciences
Biblos-e Archivo. Repositorio Institucional de la UAM
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International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 978
International Journal of Molecular Sciences, Vol 23, Iss 978, p 978 (2022)

Since the optic nerve is one of the most myelinated tracts in the central nervous system (CNS), many myelin diseases affect the visual system. In this sense, our laboratory has recently reported that the GTPases R-Ras1 and R-Ras2 are essential for ol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab6ffea5838c53ba8f2c6c03be10ff05
https://doi.org/10.3390/ijms23020978

R-ras1 and r-ras2 are essential for oligodendrocyte differentiation and survival for correct myelination in the central nervous system

Autor: Beatriz Cubelos, Agnès Gruart, Juan Escudero-Ramirez, Fernando de Castro, Miriam Sanz-Rodriguez, Francisco Wandosell, José M. Delgado-García

Publikováno v: Biblos-e Archivo: Repositorio Institucional de la UAM
Universidad Autónoma de Madrid
Biblos-e Archivo. Repositorio Institucional de la UAM
instname

Rapid and effective neural transmission of information requires correct axonal myelination. Modifications in myelination alter axonal capacity to transmit electric impulses and enable pathological conditions. In the CNS, oligodendrocytes (OLs) myelin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::956e54f6434badbf9b1184353f6b056a
http://hdl.handle.net/10486/685386