Výsledky vyhledávání - "Miriam Redrado"

Akademický článek

G9a/DNMT1 co-targeting inhibits non-small cell lung cancer growth and reprograms tumor cells to respond to cancer-drugs through SCARA5 and AOX1

Publikováno v: Cell Death and Disease, Vol 15, Iss 11, Pp 1-16 (2024)

Abstract The treatment of non-small cell lung cancer (NSCLC) patients has significantly improved with recent therapeutic strategies; however, many patients still do not benefit from them. As a result, new treatment approaches are urgently needed. In

Externí odkaz: https://doaj.org/article/6e85bcef9c6c4041a19b62d5fdc24ce3

Zobrazit plný text záznamu

Akademický článek

Two cell line models to study multiorganic metastasis and immunotherapy in lung squamous cell carcinoma

Publikováno v: Disease Models & Mechanisms, Vol 15, Iss 1 (2022)

There is a paucity of adequate mouse models and cell lines available to study lung squamous cell carcinoma (LUSC). We have generated and characterized two models of phenotypically different transplantable LUSC cell lines, i.e. UN-SCC679 and UN-SCC680

Externí odkaz: https://doaj.org/article/c6029081bc0342b6bd4394720dcdfdaf

Zobrazit plný text záznamu

Akademický článek

SRC family kinase (SFK) inhibitor dasatinib improves the antitumor activity of anti-PD-1 in NSCLC models by inhibiting Treg cell conversion and proliferation

Autor: Jackeline Agorreta, Ana Remirez, Ruben Pio, Luis M Montuenga, Teresa Lozano, Esther Redin, Irati Garmendia, Diego Serrano, Yaiza Senent, Miriam Redrado, Maria Villalba, Francisco Exposito, Daniel Ajona, Sergio Ortiz-Espinosa, Cristina Bertolo, Cristina Sainz, Juana Garcia-Pedrero, Juan Lasarte, Alfonso Calvo

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)

Introduction The use of immune-checkpoint inhibitors has drastically improved the management of patients with non-small cell lung cancer (NSCLC), but innate and acquired resistances are hurdles needed to be solved. Immunomodulatory drugs that can rei

Externí odkaz: https://doaj.org/article/168f0e31c2614696a5307d18a104e8ba

Zobrazit plný text záznamu

Akademický článek

Differential effects of drugs targeting cancer stem cell (CSC) and non-CSC populations on lung primary tumors and metastasis.

Autor: Leyre Larzabal, Nefertiti El-Nikhely, Miriam Redrado, Werner Seeger, Rajkumar Savai, Alfonso Calvo

Publikováno v: PLoS ONE, Vol 8, Iss 11, p e79798 (2013)

Cancer stem cells (CSCs) are thought to be responsible for tumor initiation and recurrence after chemotherapy. Targeting CSCs and non-CSCs with specific compounds may be an effective approach to reduce lung cancer growth and metastasis. The aim of th

Externí odkaz: https://doaj.org/article/0a4e777d8d2d40b0a291d24333dea86a

Zobrazit plný text záznamu

Data from Therapeutic Effect of Lenalidomide in a Novel Xenograft Mouse Model of Human Blastic NK Cell Lymphoma/Blastic Plasmacytoid Dendritic Cell Neoplasm

Autor: Francesco Bertolini, Alfonso Calvo, Miriam Redrado, Celia Prior, Angelica Calleri, Giuliana Gregato, Paola Marighetti, Ines Martin-Padura, Alice Agliano

Purpose: Blastic natural killer (NK) cell lymphoma/blastic plasmacytoid dendritic cell neoplasm (BNKL) is a rare and aggressive neoplasia characterized by infiltration of blast CD4+/CD56+ cells in the skin, the bone marrow, and peripheral blood. Curr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8cbbae34e00b20a9c939d6ede211f75
https://doi.org/10.1158/1078-0432.c.6520346.v1

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání