Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Miriam R. Fein"'
Autor:
Miriam R. Fein, Mikala Egeblad
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 3, Pp 580-593 (2013)
The prognosis of metastatic cancer in patients is poor. Interfering with metastatic spread is therefore important for achieving better survival from cancer. Metastatic disease is established through a series of steps, including breaching of the basem
Externí odkaz:
https://doaj.org/article/3c32b50d3943435ba9e86f94c70f4891
Publikováno v:
Current Opinion in Rheumatology. 35:249-254
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9a36b272cc64f003947e34020288a9f
https://doi.org/10.1097/bor.0000000000000940
https://doi.org/10.1097/bor.0000000000000940
Autor:
Garrett S. Dunlap, Karmela K Chan, Michael B. Brenner, Ole-Petter R. Hamnvik, A. Helena Jonsson, Aidan Tirpack, Lindsey A MacFarlane, Miriam R. Fein, Laura T. Donlin, Le Min, Edward F. DiCarlo, Susan M. Goodman, Deepak A. Rao, Anne R. Bass, Amy Cunningham-Bussel, Derrick J. Todd, Jeffrey A. Sparks, Lin Chen, Anvita Singaraju, Lorien Shakib, Kathryne E. Marks, Elena Massarotti, Runci Wang
Immune checkpoint inhibitor (ICI) therapies that promote T cell activation have improved outcomes for advanced malignancies yet also elicit harmful autoimmune reactions. The T cell mechanisms mediating these iatrogenic autoimmune events remain unclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4a481c205899cc132e94c194cf6d5d0
https://doi.org/10.1101/2021.10.19.464961
https://doi.org/10.1101/2021.10.19.464961
Publikováno v:
Bio Protoc
Flow cytometry is a popular laser-based technology that allows the phenotypic and functional characterization of individual cells in a high-throughput manner. Here, we describe a detailed procedure for preparing a single-cell suspension from mammary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c990c360c5ef4a849ca775c032cc2f86
https://pubmed.ncbi.nlm.nih.gov/34250200
https://pubmed.ncbi.nlm.nih.gov/34250200
Autor:
Haiwei Mou, Hannah Meyer, Jeremy P. McAleer, James G. Fox, Pawan Kumar, Khristian E. Bauer-Rowe, Ömer H. Yilmaz, Semir Beyaz, Charlie Chung, Eran Elinav, Vyom Shah, Stuart H. Orkin, Aysegul Erdemir, Alper Kucukural, Damodaran Annamalai, Karoline Dogum, Eider Valle-Encinas, Michael E. Xifaras, Onur Eskiocak, Miriam R. Fein, Kadir Ozler, Ilgin Ergin, Mohammad Almeqdadi, Brian Yueh, Katherine Papciak, Jatin Roper, Karthik Shekhar, Moshe Biton, Christoph A. Thaiss, Aviv Regev, Lenka Dohnalová, Aybuke Alici-Garipcan, Deniz M. Ozata
Publikováno v:
Cell Stem Cell. 28:1922-1935.e5
Little is known about how interactions of diet, intestinal stem cells (ISCs), and immune cells affect early-stage intestinal tumorigenesis. We show that a high-fat diet (HFD) reduces the expression of the major histocompatibility complex class II (MH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae5aecb4bbd4344af7800035655dcd25
https://doi.org/10.1016/j.stem.2021.08.007
https://doi.org/10.1016/j.stem.2021.08.007
Autor:
Linda Van Aelst, Emilis Bružas, Arnaud Pommier, John E. Wilkinson, Camila O. dos Santos, Anais Eberhardt, Mikala Egeblad, Xue-Yan He, Ran Yan, Miriam R. Fein, Douglas T. Fearon, Ana S. Almeida
Publikováno v:
The Journal of Experimental Medicine
C-C chemokine receptor type 2 (CCR2) expressed on monocytes facilitates their recruitment to tumors. Here, Fein et al. show that CCR2 signaling in cancer cells suppresses immune control of tumors, in part by reducing CD103+ dendritic cell recruitment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a8166b21e16f83f8f0a3b8954cb80c9
https://doi.org/10.1101/390187
https://doi.org/10.1101/390187
Publikováno v:
Journal of Nuclear Medicine. 54:3A-35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edc859e9b00bfbfb3a9477acd266737d
https://doi.org/10.2967/jnm542abs
https://doi.org/10.2967/jnm542abs
Autor:
Victoria Küttner, Youngseok Lee, Michael S. Goldberg, Yumi Kinugasa-Katayama, Kai Kessenbrock, Stephen Hearn, Juwon Park, Nam Hee Won, Zohreh Amoozgar, Julie M. Jorns, Naiara Perurena, Laura Maiorino, Mikala Egeblad, Jing Qiu, Elizabeth S. Nakasone, Ana S. Almeida, Robert W. Wysocki, Anne F. Schott, Miriam R. Fein
Publikováno v:
Science Translational Medicine. 8
Neutrophils, the most abundant type of leukocytes in blood, can form neutrophil extracellular traps (NETs). These are pathogen-trapping structures generated by expulsion of the neutrophil's DNA with associated proteolytic enzymes. NETs produced by in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c0b3ea38d72ea7f845cf01d2ac4c63
https://doi.org/10.1126/scitranslmed.aag1711
https://doi.org/10.1126/scitranslmed.aag1711
Autor:
Mina J. Bissell, Mikala Egeblad, Miriam R. Fein, Eirik Frengen, Jae-Hyun Park, Jing Qiu, Zena Werb, Hanne A. Askautrud, Vicki Plaks, Pranay Sinha, Elizabeth S. Nakasone, Juwon Park, Morten Grønbech Rasch, Ying Xim Tan, Tim Kees, Andrew J. Ewald
Publikováno v:
Cancer Cell. 21:488-503
SummaryLittle is known about the dynamics of cancer cell death in response to therapy in the tumor microenvironment. Intravital microscopy of chemotherapy-treated mouse mammary carcinomas allowed us to follow drug distribution, cell death, and tumor-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daeb7e39ef9d478318b5400544e3b28e
https://doi.org/10.1016/j.ccr.2012.02.017
https://doi.org/10.1016/j.ccr.2012.02.017
Autor:
Camila O. dos Santos, Anaïs Eberhardt, Miriam R. Fein, Emilis Bružas, Arnaud Pommier, Ana S. Almeida, Xue-Yan He, John E. Wilkinson, Mikala Egeblad
Publikováno v:
Cancer Research. 78:B42-B42
High expression of the C-C chemokine receptor type 2 (CCR2) in tumor samples and serum correlates with poor prognosis in human breast cancer, which has sparked interest in targeting the CCR2 pathway for therapeutic benefit. Importantly, a human CCR2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e62e451d69164aab9762ccfbd172a95
https://doi.org/10.1158/1538-7445.mousemodels17-b42
https://doi.org/10.1158/1538-7445.mousemodels17-b42