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pro vyhledávání: '"Miriam M. de Jel"'
Autor:
Winfried Neuhuber, Mandy Schott, Silke Kuphal, Anja-Katrin Bosserhoff, Miriam M. de Jel, Susanne Lamm
Publikováno v:
Oncogenesis, Vol 8, Iss 10, Pp 1-10 (2019)
Oncogenesis
Oncogenesis
The deubiquitinase cylindromatosis (CYLD) is a well-known tumor suppressor, found to be down regulated in many cancer types including breast cancer, colon carcinoma and malignant melanoma. CYLD is suppressed in human melanoma cells by the transcripti
Autor:
Anja K. Bosserhoff, Julia C. Engelmann, Philipp Renner, Miriam M. de Jel, Mandy Schott, Silke Kuphal, Edward K. Geissler
Publikováno v:
Oncotarget
Selenium-binding protein 1 (SELENBP1) expression is reduced in various epithelial cancer entities compared to corresponding normal tissue and has already been described as a tumor suppressor involved in the regulation of cell proliferation, senescenc
Autor:
Anja K. Bosserhoff, Manfred Kunz, Miriam M. de Jel, Silke Kuphal, Julia C. Engelmann, Susanne Schiffner
Publikováno v:
Pigment cellmelanoma research. 27(4)
Malignant melanoma is thought to exhibit a high base mutation rate compared with other solid tumors. Therefore, there is a strong interest in discovering new mutations and understanding their impact on melanoma pathogenesis. Mutations in several gene
Autor:
Anja K. Bosserhoff, Barbara M. Braunger, Susanne Schiffner, Ernst R. Tamm, Miriam M. de Jel, Sarah E. Coupland
Publikováno v:
Experimental eye research. 127
Although rare, uveal melanoma (UM) is the most common primary intraocular tumor in adults. About half of UM patients develop metastatic disease typically in the liver and die within a short period, due to ineffective systemic therapies. UM has unique