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of 91
pro vyhledávání: '"Miriam M. Salpeter"'
Publikováno v:
Journal of Neurochemistry. 84:180-188
The degradation rates of acetylcholine receptors (AchRs) were evaluated at the neuromuscular junction during and just after reinnervation of denervated muscles. When mouse sternomastoid muscles are denervated by multiple nerve crush, reinnervation be
Autor:
Rufeng Xu, Miriam M. Salpeter
Publikováno v:
Journal of Cellular Physiology. 181:107-112
The rate constants for internalization and subsequent extrusion of acetylcholine receptors (AChRs) during degradation in adult innervated and denervated mouse diaphragm muscles were determined using proteinase K (PK) digestion. This procedure separat
Autor:
Rufeng Xu, Miriam M. Salpeter
Publikováno v:
The Journal of Neuroscience. 17:8194-8200
Acetylcholine receptors (AChRs) are present at the top of the postsynaptic membrane of the neuromuscular junction (NMJ) at very high density, possibly anchored to cytoskeletal elements. The present study investigated whether AChR degradation is affec
Publikováno v:
The Journal of Cell Biology
Innervation of the neuromuscular junction (nmj) affects the stability of acetylcholine receptors (AChRs). A neural factor that could affect AChR stabilization was studied using cultured muscle cells since they express two distinct populations of AChR
Publikováno v:
Neuroscience Letters. 174:77-80
Mouse acetylcholine receptors (AChRs) consisting of either the embryonic form (2 alpha, 1 beta, 1 delta and 1 gamma) or the adult form (2 alpha, 1 beta, 1 delta and 1 epsilon) were expressed in Xenopus laevis oocytes. As expected, the single channel
Publikováno v:
Experimental Cell Research. 208:44-47
Acetylcholine receptors (AChRs) of rat muscle cells grown in culture for 4 days were labeled with 125 I-α-bungarotoxin and their degradation rate measured. Two AChR populations, a rapidly degrading one (R r , t 1/2 ∼1 day) and a slowly degrading o
Publikováno v:
The Journal of Cell Biology
Hong Kong University of Science and Technology
Hong Kong University of Science and Technology
In situ hybridization of chick cultured muscle cells using exonic DNA probes for both AChR alpha-sub-unit and the catalytic subunit of AChE, revealed major differences in the distribution of label both over nuclei and in their surrounding cytoplasm,
Publikováno v:
Biophysical Journal. 59:1290-1307
A Monte Carlo method for modeling the neuromuscular junction is described in which the three-dimensional structure of the synapse can be specified. Complexities can be introduced into the acetylcholine kinetic model used with only a small increase in
Autor:
Miriam M. Salpeter, SL Shyng
Publikováno v:
The Journal of Neuroscience. 10:3905-3915
Two populations of ACh receptors (AChRs) with different degradation rates have been shown to coexist in the postsynaptic membrane after denervation of the neuromuscular junction (NMJ). One population, consisting of the slowly degrading original AChRs
Publikováno v:
Journal of neurochemistry. 84(1)
The degradation rates of acetylcholine receptors (AchRs) were evaluated at the neuromuscular junction during and just after reinnervation of denervated muscles. When mouse sternomastoid muscles are denervated by multiple nerve crush, reinnervation be