Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Miriam M. Geist"'
Autor:
Christian Ostalecki, Sebastian Wittki, Jung-Hyun Lee, Miriam M. Geist, Nadine Tibroni, Thomas Harrer, Gerold Schuler, Oliver T. Fackler, Andreas S. Baur
Publikováno v:
EBioMedicine, Vol 13, Iss C, Pp 294-304 (2016)
Tumor necrosis factor (TNF) is a key cytokine in HIV replication and pathogenesis. For reasons that are not entirely clear, the cytokine remains upregulated despite anti-retroviral therapy (ART). Here we demonstrate that HIV Nef induces an alternativ
Externí odkaz:
https://doaj.org/article/a1af026f04114ee2aa3a5b4a1ad4d757
Autor:
Shemsi Demolli, Miriam M. Geist, Julia E. Weigand, Nicole Matschiavelli, Beatrix Suess, Michael Rother
Publikováno v:
Archaea, Vol 2014 (2014)
The use of reporter gene fusions to assess cellular processes such as protein targeting and regulation of transcription or translation is established technology in archaeal, bacterial, and eukaryal genetics. Fluorescent proteins or enzymes resulting
Externí odkaz:
https://doaj.org/article/72a1a29f7f3940c7a335cf1613305375
Autor:
Silke Bender, Xiaoyu Pan, Oliver T. Fackler, Walter Nickel, Miriam M. Geist, Ralf Bartenschlager
Publikováno v:
Journal of Biological Chemistry. 289:14030-14044
The HIV-1 pathogenicity factor Nef enhances viral replication by modulation of multiple host cell transport and signaling pathways. Nef associates with membranes via an N-terminal Src homology 4 (SH4) domain, and membrane association is believed to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e850fa6a082cddbee0967a36619635c5
https://doi.org/10.1074/jbc.m114.563528
https://doi.org/10.1074/jbc.m114.563528
Publikováno v:
Retrovirology
Background The Nef protein is a pathogenicity factor of HIV-1 that substantially increases virus replication in vivo by modulation of multiple host cell transport and signal transduction processes. Nef resides at the inner leaflet of the plasma membr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593a1321320cc99683e4d7eda3bda2c1
https://doi.org/10.1186/1742-4690-10-s1-p36
https://doi.org/10.1186/1742-4690-10-s1-p36
Publikováno v:
Cellular Microbiology.
HIV-1 Nef, an essential factor in AIDS pathogenesis, boosts virus replication in vivo. As one of its activities in CD4(+) T-lymphocytes, Nef potently retargets the Src family kinase (SFK) Lck but not closely related Fyn from the plasma membrane to re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09d9f5e4297c06615b3c6b7047b44c39
https://doi.org/10.1111/cmi.12148
https://doi.org/10.1111/cmi.12148
Publikováno v:
Cellular microbiology. 15(10)
HIV-1 Nef, an essential factor in AIDS pathogenesis, boosts virus replication in vivo. As one of its activities in CD4(+) T-lymphocytes, Nef potently retargets the Src family kinase (SFK) Lck but not closely related Fyn from the plasma membrane to re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a178c778935b7ce84bb348488c23a005
https://pubmed.ncbi.nlm.nih.gov/23601552
https://pubmed.ncbi.nlm.nih.gov/23601552