Zobrazeno 1 - 10
of 230
pro vyhledávání: '"Miriam L, Greenberg"'
Autor:
Zhuqing Liang, Tyler Ralph-Epps, Michael W. Schmidtke, Pablo Lazcano, Simone W. Denis, Mária Balážová, Nevton Teixeira da Rosa, Mohamed Chakkour, Sanaa Hazime, Mindong Ren, Michael Schlame, Riekelt H. Houtkooper, Miriam L. Greenberg
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Barth syndrome (BTHS) is a rare disorder caused by mutations in the TAFAZZIN gene. Previous studies from both patients and model systems have established metabolic dysregulation as a core component of BTHS pathology. In particular, features
Externí odkaz:
https://doaj.org/article/0764c46ec838464c99b44c7af0e10035
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Inositol depletion is a hypothesized mechanism of action of mood stabilization drugs used in the treatment of bipolar disorder. It was previously reported that the mood stabilizer valproate (VPA) increased phosphorylation of myo-inositol-3-p
Externí odkaz:
https://doaj.org/article/9bbc3fd556db46e7b6496f7f177b13e7
Autor:
Zhuqing Liang, Tyler Ralph-Epps, Michael W. Schmidtke, Pablo Lazcano, Simone W. Denis, Mária Balážová, Nevton Teixeira da Rosa, Mohamed Chakkour, Sanaa Hazime, Mindong Ren, Michael Schlame, Riekelt H. Houtkooper, Miriam L. Greenberg
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/69d323fe70974129940cd583a5da7ab1
Autor:
Anil Kumar Vijjamarri, Xiao Niu, Matthew D Vandermeulen, Chisom Onu, Fan Zhang, Hongfang Qiu, Neha Gupta, Swati Gaikwad, Miriam L Greenberg, Paul J Cullen, Zhenguo Lin, Alan G Hinnebusch
Publikováno v:
eLife, Vol 12 (2023)
Degradation of most yeast mRNAs involves decapping by Dcp1/Dcp2. DEAD-box protein Dhh1 has been implicated as an activator of decapping, in coupling codon non-optimality to enhanced degradation, and as a translational repressor, but its functions in
Externí odkaz:
https://doaj.org/article/aa2f0c85f238450c866b4e82f7ac3f97
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Barth syndrome (BTHS, OMIM 302060) is a genetic disorder caused by variants of the TAFAZZIN gene (G 4.5, OMIM 300394). This debilitating disorder is characterized by cardio- and skeletal myopathy, exercise intolerance, and neutropenia. TAFAZZIN is a
Externí odkaz:
https://doaj.org/article/7a766939d28c4f87b93036bb9fa65a62
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Saccharomyces cerevisiae, commonly known as baker’s yeast, is one of the most comprehensively studied model organisms in science. Yeast has been used to study a wide variety of human diseases, and the yeast model system has proved to be an especial
Externí odkaz:
https://doaj.org/article/8e0ed2e1b0b947ce8aee0b1a51ad1a1e
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Bipolar disorder (BD) is a mood disorder that affects millions worldwide and is associated with severe mood swings between mania and depression. The mood stabilizers valproate (VPA) and lithium (Li) are among the main drugs that are used to treat BD
Externí odkaz:
https://doaj.org/article/3efc9d14e11d48638f88e999e8f4fccd
Publikováno v:
Cancer and Metastasis Reviews. 41:249-254
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62d5b1de365948be455136bf1b09914d
https://doi.org/10.1007/s10555-022-10032-8
https://doi.org/10.1007/s10555-022-10032-8
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182534 (2017)
Myo-inositol, the precursor of all inositol compounds, is essential for the viability of eukaryotes. Identifying the factors that regulate inositol homeostasis is of obvious importance to understanding cell function and the pathologies underlying neu
Externí odkaz:
https://doaj.org/article/31b1bfe11eca47b2baa1c7d07dabfd6f
Autor:
David Blazar, Thomas J. Kane, Daniel Thal, David M. Quinn, Miriam L. Greenberg, Hunter Gehlbach
Publikováno v:
Education Finance and Policy. 15:397-427
Teacher evaluation reform has been among the most controversial education reforms in recent years. It also is one of the costliest in terms of the time teachers and principals must spend on classroom observations. We conducted a randomized field tria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f3e790a287b5c500f41171df8926fef
https://doi.org/10.1162/edfp_a_00289
https://doi.org/10.1162/edfp_a_00289