Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Miriam Kron"'
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 9, Pp 1047-1055 (2014)
Reduced levels of brain-derived neurotrophic factor (BDNF) are thought to contribute to the pathophysiology of Rett syndrome (RTT), a severe neurodevelopmental disorder caused by loss-of-function mutations in the gene encoding methyl-CpG-binding prot
Externí odkaz:
https://doaj.org/article/2efcf3fc0cfb485eae76a8d652e13fa8
Autor:
David M. Katz, Joanne E. Berger-Sweeney, James H. Eubanks, Monica J. Justice, Jeffrey L. Neul, Lucas Pozzo-Miller, Mary E. Blue, Diana Christian, Jacqueline N. Crawley, Maurizio Giustetto, Jacky Guy, C. James Howell, Miriam Kron, Sacha B. Nelson, Rodney C. Samaco, Laura R. Schaevitz, Coryse St. Hillaire-Clarke, Juan L. Young, Huda Y. Zoghbi, Laura A. Mamounas
Publikováno v:
Disease Models & Mechanisms, Vol 5, Iss 6, Pp 733-745 (2012)
In September of 2011, the National Institute of Neurological Disorders and Stroke (NINDS), the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the International Rett Syndrome Foundation (IRSF) and the Rett Syn
Externí odkaz:
https://doaj.org/article/e47f996a0ef64ccab86e468a2e1e40e3
Autor:
Marcus Niebert, Steffen Vogelgesang, Uwe R Koch, Anna-Maria Bischoff, Miriam Kron, Nathalie Bock, Till Manzke
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21395 (2011)
Neurons of the respiratory network in the lower brainstem express a variety of serotonin receptors (5-HTRs) that act primarily through adenylyl cyclase. However, there is one receptor family including 5-HT(2A), 5-HT(2B), and 5-HT(2C) receptors that a
Externí odkaz:
https://doaj.org/article/43373990b01042e7b5dd6ca2627278cd
Publikováno v:
Journal of Neurophysiology. 105:3067-3079
Rett syndrome (RTT) patients suffer from respiratory arrhythmias with frequent apneas causing intermittent hypoxia. In a RTT mouse model (methyl-CpG-binding protein 2-deficient mice; Mecp2−/ y) we recently discovered an enhanced hippocampal suscept
Autor:
Michael Müller, Miriam Kron
Publikováno v:
Neuroscience. 171:300-315
Methyl-CpG-binding protein 2 (MeCP2) deficiency causes Rett syndrome (RTT), a neurodevelopmental disorder characterized by severe cognitive impairment, synaptic dysfunction, and hyperexcitability. Previously we reported that the hippocampus of MeCP2-
Autor:
Michael Mörschel, Weiqi Zhang, Miriam Kron, Julia Reuter, Mathias Dutschmann, Christian Gestreau, Georg M. Stettner
Publikováno v:
Respiratory Physiology & Neurobiology. 164:72-79
The shape of the three-phase respiratory motor pattern (inspiration, postinspiration, late expiration) is controlled by a central pattern generator (CPG) located in the ponto-medullary brainstem. Synaptic interactions between and within specific sub-
Publikováno v:
The Journal of Physiology. 586:2331-2343
The Kolliker–Fuse nucleus (KF) contributes essentially to respiratory pattern formation and adaptation of breathing to afferent information. Systems physiology suggests that these KF functions depend on NMDA receptors (NMDA-R). Recent investigation
Publikováno v:
mSystems, Vol 8, Iss 2 (2023)
ABSTRACT Recent discoveries of isoprene-metabolizing microorganisms suggest they might play an important role in the global isoprene budget. Under anoxic conditions, isoprene can be used as an electron acceptor and is reduced to methylbutene. This st
Externí odkaz:
https://doaj.org/article/bfa1da6a69c84b78aea37ec1bb6ad24a
Publikováno v:
European Journal of Neuroscience. 26:3449-3457
The Kolliker–Fuse nucleus (KF), part of the pontine respiratory group, is involved in the control of respiratory phase duration, and receives both excitatory and inhibitory afferent input from various other brain regions. There is evidence for deve
Publikováno v:
Respiratory Physiology & Neurobiology. 159:232-235
Orexins (splice variants A and B) are hypothalamic neuropeptides that have essential functions in control of arousal and nutrition. Lack of Orexins is strongly associated with narcolepsy and sleep disordered breathing. However, the role of Orexins an