Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Miriam K. Vanhook"'
Publikováno v:
Molecular Pharmacology. 69:492-500
Tight junctions are directly involved in regulating the passage of ions and macromolecules (gate functions) in epithelial and endothelial cells. The modulation of these gate functions to transiently regulate the paracellular permeability of large sol
Autor:
Carolyn B. Coyne, Najwa Haykal-Coates, Stephen H. Gavett, Miriam K. Vanhook, Larry G. Johnson
Publikováno v:
Human Gene Therapy. 14:729-747
We evaluated the safety of agents that enhance gene transfer by modulating paracellular permeability. Lactate dehydrogenase (LDH) and cytokine release were measured in polarized primary human airway epithelial (HAE) cells after lumenal application of
Autor:
Johnny L. Carson, Todd M. Gambling, Carolyn B. Coyne, Larry G. Johnson, Miriam K. Vanhook, Richard C. Boucher
Publikováno v:
Molecular Biology of the Cell. 13:3218-3234
Epithelial tight junctions (TJs) provide an important route for passive electrolyte transport across airway epithelium and provide a barrier to the migration of toxic materials from the lumen to the interstitium. The possibility that TJ function may
Publikováno v:
Molecular Therapy. 11:S140-S141
Tight junctions (TJs) are directly involved in the gate functions of epithelial and endothelial cells. The transient up-or down-regulation of these gate functions could have a therapeutic advantage in the treatment of lung diseases via delivery of ph
Publikováno v:
Molecular Therapy. 9:S191
Pulmonary hypertension may be a potential disease target for alveolar gene transfer by luminal delivery. We hypothesize that long-term expression of prostacyclin synthase (PGIS) cDNA can ameliorate the manifestations of pulmonary hypertension in mous
Autor:
Larry G. Johnson, Miriam K. Vanhook, Carolyn B. Coyne, Najwa Haykal-Coates, Stephen H. Gavett
Publikováno v:
Human Gene Therapy; 5/20/2003, Vol. 14 Issue 8, p729-747, 19p