Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Miriam H. Fukami"'
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1714:125-133
The effects of resveratrol (trans-3,4′,5-trihydroxystilbene) on activation responses and the polyphosphoinositide metabolism in human blood platelets have been studied. Resveratrol partially inhibited secretory responses (liberation of dense granul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d1a51fe9d169499f4167cf6a4220974
https://doi.org/10.1016/j.bbamem.2005.06.008
https://doi.org/10.1016/j.bbamem.2005.06.008
Publikováno v:
Platelets. 13:437-442
The effects of Mg2+ and EDTA on collagen-induced platelet dense granule secretion and protein tyrosine phosphorylation were studied in the presence and absence of various inhibitors of autocrine agonists that are released from secretory granules. Add
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d512fdb6dc9ca36ed84b74440e74fe74
https://doi.org/10.1080/0953710021000057794
https://doi.org/10.1080/0953710021000057794
Publikováno v:
Biochemical Journal. 350:469-475
Human platelets release platelet-derived growth factor (PDGF) from α-granules during platelet activation. We have previously shown that platelets have PDGF α-receptors, a transmembrane tyrosine kinase that takes part in negative feedback regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a38fab37f51e90ba7a9b94a97556b85
https://doi.org/10.1042/bj3500469
https://doi.org/10.1042/bj3500469
Publikováno v:
Platelets. 7:313-320
Platelets contain three types of secretory granules, dense granules, α-granules and lysosomes, which are characterized by their different contents. Dense granule and α-granule secretion appear to be similar in responsiveness to dose and types of ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a864b26f198f990dd9a7e39b75227f2
https://doi.org/10.3109/09537109609023594
https://doi.org/10.3109/09537109609023594
Autor:
Miriam H. Fukami, Holm Holmsen
Publikováno v:
European Journal of Biochemistry. 228:579-586
Several laboratories have reported that diacylglycerol levels in human platelets (approximately 100 pmol/10(9) platelets) increased severalfold in response to 0.5-1 U/ml thrombin. We report here fluctuations in diacylglycerol mass in control platelet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177b20b66e1d29092a3d0732ea044324
https://doi.org/10.1111/j.1432-1033.1995.tb20297.x
https://doi.org/10.1111/j.1432-1033.1995.tb20297.x
Publikováno v:
Thrombosis Research. 67:313-323
It has become customary to regard the various glycerophospholipids as quite similar, and the acyl groups are considered to have little influence on the behaviour of the lipids in membranes or metabolism. Nevertheless, a number of recent observations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f43a1b2628dcc3ea41775cace632a0
https://doi.org/10.1016/0049-3848(92)90006-v
https://doi.org/10.1016/0049-3848(92)90006-v
Publikováno v:
Platelets. 13(5-6)
Incubation of blood platelets with (32)P-labelled inorganic phosphate for 60 min leads to incorporation of radioisotope mainly into phosphatidylinositol (PI), phosphatidylinositol-4-phosphate (PIP) and phosphatidyl-4,5-bisphosphate (PIP(2)) in restin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e6d6d367501b3812f597cbac3e23a7
https://pubmed.ncbi.nlm.nih.gov/12189013
https://pubmed.ncbi.nlm.nih.gov/12189013
Autor:
Holm Holmsen, Miriam H. Fukami, Vidar A.T. Thorsen, Bodil Bjørndal, Johan R. Lillehaug, Ove Bruland, Gary P. Nolan
Publikováno v:
Biochimica et biophysica acta. 1487(2-3)
The C3H/10T1/2 Cl8 HAbetaC2-1 cells used in this study express a peptide with a sequence shown to bind receptor for activated C-kinase (RACK1) and inhibit cPKC-mediated cell functions. Phorbol myristoyl acetate (PMA) strongly stimulated phosphatidylc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49677fed5e25d1a8c7dfac779610500d
https://pubmed.ncbi.nlm.nih.gov/11018469
https://pubmed.ncbi.nlm.nih.gov/11018469
Publikováno v:
Biochemical pharmacology. 60(9)
The actions of eight cationic amphiphilic drugs on human platelets displayed three different effects according to drug concentration ranges. At lower concentrations (below approximately 25 microM), the drugs stimulated secretory responses induced by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::835c6f24c3db90b090b9c59e1a59f7cf
https://pubmed.ncbi.nlm.nih.gov/11008120
https://pubmed.ncbi.nlm.nih.gov/11008120
Publikováno v:
Biochemical and biophysical research communications. 263(3)
Platelet activation by thrombin or collagen results in secretion and synthesis of several platelet agonists that enhance the responses to the primary agonists (autocrine stimulation). To disclose the effects of thrombin and collagen on the phosphoryl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0458f387dd6e6c30b2b246cc77ce600c
https://pubmed.ncbi.nlm.nih.gov/10512757
https://pubmed.ncbi.nlm.nih.gov/10512757