Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Miriam Falzon"'
Publikováno v:
Pancreas
OBJECTIVE Chronic pancreatitis is the consequence of multiple episodes of recurrent acute pancreatitis (RAP). We hypothesized that apigenin can minimize the sequelae of RAP by limiting acinar cells' proinflammatory signaling pathways. METHODS AR42J a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::873cccb8d3021ea4dc5c530f77a9350d
https://doi.org/10.1097/mpa.0000000000001310
https://doi.org/10.1097/mpa.0000000000001310
Autor:
Yanna Cao, Ka Liu, Vandanajay Bhatia, Tien C. Ko, Xuxia Gao, Song Han, George H. Greeley, Miriam Falzon, Cristiana Rastellini
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 309:G554-G565
Chronic pancreatitis (CP) is a devastating disease with no treatments. Experimental models have been developed to reproduce the parenchyma and inflammatory responses typical of human CP. For the present study, one objective was to assess and compare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7521e942db05638c989e4101d7a693a2
https://doi.org/10.1152/ajpgi.00076.2015
https://doi.org/10.1152/ajpgi.00076.2015
Autor:
Vandanajay Bhatia, Miriam Falzon
Publikováno v:
Cancers
Cancers, Vol 7, Iss 2, Pp 1091-1108 (2015)
Cancers, Vol 7, Iss 2, Pp 1091-1108 (2015)
Chronic pancreatitis (CP), a progressive inflammatory disease where acini are destroyed and replaced by fibrous tissue, increases the risk for pancreatic cancer. Risk factors include alcohol, smoking, and obesity. The effects of these risk factors ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c8ede29801f57d83e84345d69e89b84
http://europepmc.org/articles/PMC4491701
http://europepmc.org/articles/PMC4491701
Autor:
George H. Greeley, Vandanajay Bhatia, Miriam Falzon, Judith F. Aronson, Cristiana Rastellini, Song Han
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 307:G533-G549
Pancreatitis is a necroinflammatory disease with acute and chronic manifestations. Accumulated damage incurred during repeated bouts of acute pancreatitis (AP) can lead to chronic pancreatitis (CP). Pancreatic parathyroid hormone-related protein (PTH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef4a112dfb2b9bdfe0db4bf34843ca2
https://doi.org/10.1152/ajpgi.00428.2013
https://doi.org/10.1152/ajpgi.00428.2013
Publikováno v:
Experimental Cell Research. 319:1419-1430
Parathyroid hormone-related protein (PTHrP) enhances prostate cancer (CaP) growth and metastasis in vivo. PTHrP also increases cell survival and migration, and upregulates pro-invasive integrin α6β4 expression. We used the human CaP cell lines C4-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::059fcf1201208e6ffbaef05613c79345
https://doi.org/10.1016/j.yexcr.2013.03.003
https://doi.org/10.1016/j.yexcr.2013.03.003
Publikováno v:
Cancer Letters. 298:119-127
Parathyroid hormone-related protein (PTHrP) is expressed by human colon cancer tissue and cell lines. Rac1 GTPase enhances colon cancer cell migration and invasion. Here we report a positive correlation between PTHrP expression and Rac1 activity in L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29a3af3248bc7eca71eaeec7044b10b
https://doi.org/10.1016/j.canlet.2010.06.009
https://doi.org/10.1016/j.canlet.2010.06.009
Publikováno v:
Regulatory Peptides. 158:149-155
Parathyroid hormone-related protein (PTHrP) is expressed by human colon cancer tissue and cell lines; expression correlates with colon carcinoma severity. PTHrP is synthesized as a prepro isoform and contains two targeting sequences – a signal sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66cdbb0c87efacb70b3d9623f0d63ccf
https://doi.org/10.1016/j.regpep.2009.07.008
https://doi.org/10.1016/j.regpep.2009.07.008
Publikováno v:
Cancer Letters. 258:241-252
Parathyroid hormone-related protein (PTHrP) is expressed by human colon cancer tissue and cell lines. Expression of PTHrP and phosphatidylinositol 3-kinase (PI3-K) pathway components correlates with the severity of colon carcinoma. Here we observed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8372803f2020c3479369fe9e4c7c33d1
https://doi.org/10.1016/j.canlet.2007.09.010
https://doi.org/10.1016/j.canlet.2007.09.010
Publikováno v:
Regulatory Peptides. 141:61-72
Parathyroid hormone-related protein (PTHrP) has been localized in human colon cancer tissue and cell lines. We have previously shown that PTHrP increases colon cancer cell proliferation, extracellular matrix adhesion, and cell-surface integrin alpha6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f234148e3c8ce34c91b3882f0f5340c
https://doi.org/10.1016/j.regpep.2006.12.017
https://doi.org/10.1016/j.regpep.2006.12.017
Publikováno v:
Pancreas. 45(5)
Objectives Transforming growth factor β (TGF-β) regulates immune and fibrotic responses of chronic pancreatitis. The bone morphogenetic protein 2 (BMP-2) antagonist gremlin is regulated by TGF-β. Parathyroid hormone-related protein (PTHrP) levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e85ae8166d213b9e01752f59e538dbe
https://pubmed.ncbi.nlm.nih.gov/27077711
https://pubmed.ncbi.nlm.nih.gov/27077711