Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Miriam Ejarque"'
Autor:
Bruno Blanchi, Marion Taurand, Claire Colace, Sofia Thomaidou, Charlotte Audeoud, Federica Fantuzzi, Toshiaki Sawatani, Sevda Gheibi, Joan Sabadell-Basallote, Fransje W.J. Boot, Thibault Chantier, Aline Piet, Charlotte Cavanihac, Marion Pilette, Adélie Balguerie, Hamza Olleik, Françoise Carlotti, Miriam Ejarque, Malin Fex, Hindrik Mulder, Miriam Cnop, Decio L. Eizirik, Ouardane Jouannot, Anne-Lise Gaffuri, Paul Czernichow, Arnaud Zaldumbide, Raphaël Scharfmann, Philippe Ravassard
Publikováno v:
Molecular Metabolism, Vol 76, Iss , Pp 101772- (2023)
Objectives: Readily accessible human pancreatic beta cells that are functionally close to primary adult beta cells are a crucial model to better understand human beta cell physiology and develop new treatments for diabetes. We here report the charact
Externí odkaz:
https://doaj.org/article/2150f4f22a72439bb1a63dbdb430ec0a
Autor:
Florence Blot, Justine Marchix, Miriam Ejarque, Sara Jimenez, Aline Meunier, Céline Keime, Camille Trottier, Mikaël Croyal, Céline Lapp, Maxime M. Mahe, Adèle De Arcangelis, Gérard Gradwohl
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 6, Pp 1443-1461 (2023)
Background & Aims: Enteroendocrine cells (EECs) and their hormones are essential regulators of whole-body energy homeostasis. EECs sense luminal nutrients and microbial metabolites and subsequently secrete various hormones acting locally or at a dist
Externí odkaz:
https://doaj.org/article/7d6378a8c849424181d069f1a1425799
Autor:
Enrique Calvo, Noelia Keiran, Catalina Núñez-Roa, Elsa Maymó-Masip, Miriam Ejarque, Joan Sabadell-Basallote, María del Mar Rodríguez-Peña, Victòria Ceperuelo-Mallafré, Jesús Seco, Ester Benaiges, Theodora Michalopoulou, Rosa Jorba, Joan Vendrell, Sonia Fernández-Veledo
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Adipose-derived mesenchymal stem cells (ASCs) are a promising option for the treatment of obesity and its metabolic co-morbidities. Despite the recent identification of brown adipose tissue (BAT) as a potential target in the management of ob
Externí odkaz:
https://doaj.org/article/27e8a7169a344c70913c6bfca80e9cd0
Autor:
Miriam Ejarque, Joan Sabadell‐Basallote, Ester Benaiges, Catalina Núñez‐Roa, Eduardo Sabido, Eva Borras, Erik Llacer, Antonio Zorzano, Joan Vendrell, Sonia Fernández‐Veledo
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 6, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/dcc5c8b41b5d4fc8bb83542bb191338c
Autor:
Francisco Algaba‐Chueca, Elsa Maymó‐Masip, Miriam Ejarque, Mónica Ballesteros, Gemma Llauradó, Carlos López, Albert Guarque, Carolina Serena, Laia Martínez‐Guasch, Cristina Gutiérrez, Ramón Bosch, Joan Vendrell, Ana Megía, Sonia Fernández‐Veledo
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 3, Pp 351-363 (2020)
Abstract Fetal programming has been proposed as a key mechanism underlying the association between intrauterine exposure to maternal diabetes and negative health outcomes in offspring. To determine whether gestational diabetes mellitus (GDM) might le
Externí odkaz:
https://doaj.org/article/d8535325c56d437fa08c8e4501703d89
DNA Methylation in Gestational Diabetes and its Predictive Value for Postpartum Glucose Disturbances
Autor:
Mónica Ballesteros, Pilar Gil-Lluís, Miriam Ejarque, Cristina Diaz-Perdigones, Laia Martinez-Guasch, Sonia Fernández-Veledo, Joan Vendrell, Ana Megía
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 107:2748-2757
Context DNA methylation in the diagnosis of gestational diabetes. Objective To assess the value of DNA methylation in the diagnosis of gestational diabetes (GDM) and in the prediction of maternal postpartum glucose disturbances. Methods Two-stage obs
Autor:
Carolina Serena, Noelia Keiran, Ana Madeira, Elsa Maymó-Masip, Miriam Ejarque, Margarida Terrón-Puig, Eloy Espin, Marc Martí, Natalia Borruel, Francisco Guarner, Margarida Menacho, Antonio Zorzano, Monica Millan, Sonia Fernández-Veledo, Joan Vendrell
Publikováno v:
Stem Cell Reports, Vol 9, Iss 4, Pp 1109-1123 (2017)
Crohn's disease (CD) is characterized by the expansion of mesenteric fat, also known as “creeping fat.” We explored the plasticity and immune properties of adipose-derived stem cells (ASCs) in the context of CD as potential key players in the dev
Externí odkaz:
https://doaj.org/article/2d806e6db95f4a768707a0754ad50a47
Autor:
Ana Madeira, Carolina Serena, Miriam Ejarque, Elsa Maymó-Masip, Monica Millan, M. Carmen Navarro-Ruiz, Rocío Guzmán-Ruiz, María M. Malagón, Eloy Espin, Marc Martí, Margarita Menacho, Ana Megía, Joan Vendrell, Sonia Fernández-Veledo
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8, p 4292 (2021)
Our understanding of the interplay between human adipose tissue and the immune system is limited. The mesothelium, an immunologically active structure, emerged as a source of visceral adipose tissue. After investigating the mesothelial properties of
Externí odkaz:
https://doaj.org/article/29357484198b4649884845599bb2b0d6
Autor:
Victòria Ceperuelo-Mallafré, Miriam Ejarque, Carolina Serena, Xavier Duran, Marta Montori-Grau, Miguel Angel Rodríguez, Oscar Yanes, Catalina Núñez-Roa, Kelly Roche, Prasanth Puthanveetil, Lourdes Garrido-Sánchez, Enrique Saez, Francisco J. Tinahones, Pablo M. Garcia-Roves, Anna Ma Gómez-Foix, Alan R. Saltiel, Joan Vendrell, Sonia Fernández-Veledo
Publikováno v:
Molecular Metabolism, Vol 5, Iss 1, Pp 5-18 (2016)
Objective: Glycogen metabolism has emerged as a mediator in the control of energy homeostasis and studies in murine models reveal that adipose tissue might contain glycogen stores. Here we investigated the physio(patho)logical role of glycogen in hum
Externí odkaz:
https://doaj.org/article/fd5e2d64a54b4718a269b27ec17db6d1
Autor:
Margarida Terrón‐Puig, Isabel Huber‐Ruano, Joan Sabadell‐Basallote, Miriam Ejarque, Catalina Núñez‐Roa, Elsa Maymó‐Masip, Rosa Jorba, Carolina Serena, Joan Vendrell, Sonia Fernández‐Veledo
Publikováno v:
Aging Cell. 21
Dysfunctional adipocyte precursors have emerged as key determinants for obesity- and aging-related inflammation, but the mechanistic basis remains poorly understood. Here, we explored the dysfunctional adipose tissue of elderly and obese individuals