Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Miriam D. Rosenthal"'
Autor:
Robert H. Glew, Miriam D. Rosenthal
This text uses a case-study approach to present core principles of biochemistry and molecular biology in the context of human disease. The thirty-three cases have been carefully chosen to cover key concepts and common diseases. Each chapter provides
Publikováno v:
Endocrine. 23:219-228
Although estrogen plays a central integrative role in regulating key aspects of placental and fetal endocrine development in the primate, our understanding of the regulation of maturation of the fetal liver is incomplete. In adults, estrogen modulate
Autor:
Miriam D Rosenthal
Publikováno v:
Government Information Quarterly. 17:193-208
This article reports the results of research and analysis undertaken by Census Bureau staff. It has undergone a more limited review than official Census Bureau publications.
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 83:2861-2867
Although the human placenta at term exhibits high levels of phospholipase A2 (PLA2) enzyme activity, our understanding of the ontogenesis, regulation, and specific roles of placental phospholipases A2 remains relatively incomplete. Using the baboon a
Autor:
L.K. Harris, Miriam D. Rosenthal, Richard C. Franson, E.S. Buescher, M.N. Gordon, J.H. Slusser
Publikováno v:
Biochemical and Biophysical Research Communications. 208:650-656
Although "secretory" type II 14-kDa phospholipase A2 (sPLA2) activity has been described in neutrophils, direct evidence of enzyme secretion has been elusive. We have used immunogold electron microscopy with polyclonal and monoclonal antibodies to sP
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1177:79-86
Preincubation of human neutrophils with 1-oleoyl-2-acetylglycerol (OAG) enhances subsequent f-Met-Leu-Phe (fMLP)-stimulated arachidonate mobilization. We have recently demonstrated that preincubation of neutrophils with OAG also reverses inhibition o
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1136:169-174
Sphingosine inhibits protein kinase C activity in vitro and has been used to implicate this enzyme in signal transduction and cell function. We report that sphingosine directly inhibits phospholipases A2 and D. Sphingosine inhibits Ca(2+)-dependent p
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1126:319-326
Aristolochic acid and PGBx, two structurally unrelated, protein-targeted inhibitors of isolated phospholipases A2, are effective antagonists of calcium ionophore A23187-stimulated mobilization of [3H]arachidonate from human neutrophils. We now report
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1083:29-36
This study has investigated the metabolic modification of [3-14C]docosatetraenoate (22:4(n−6)) and [3-14C]docosapentaenoate (22:5(n−3)) by human cells in culture. Fetal skin fibroblasts converted as much as 20% of the incoporated [ 14 C ]22:4(n
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1083:37-45
This study has investigated the effect of supplementation of vascular endothelial cells with arachidonate and other polyunsaturated fatty acids on the agonist-stimulated synthesis of platelet activating factor (PAF; 1- O -alkyl-2-acetyl- sn -glycero-