Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Miriam Crowe"'
Publikováno v:
Frontiers in Pediatrics, Vol 8 (2020)
Objective: There has been a significant change within clinical practice in childhood disability from “treating” at the level of body function to ecological approaches that address the child's involvement in everyday life. Clinical assessment, and
Externí odkaz:
https://doaj.org/article/a3d3ff63bba146dda56836b5cc12a4b4
Publikováno v:
Frontiers in Pediatrics
Frontiers in Pediatrics, Vol 8 (2020)
Frontiers in Pediatrics, Vol 8 (2020)
Objective: There has been a significant change within clinical practice in childhood disability from "treating" at the level of body function to ecological approaches that address the child's involvement in everyday life. Clinical assessment, and rob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0961383ef2f8df96ee0482b3e1525df5
http://europepmc.org/articles/PMC7272698
http://europepmc.org/articles/PMC7272698
Autor:
James Michael Woolven, Simon Teanby Hodgson, Miriam Crowe, Linda J. Russell, Wendy Karen Alderton, John Dawson, C. Lynn Chambers, Christopher Charles Frederick Hamlett, Richard G. Knowles, Richard Stocker, Robert J. Young, Paul John Beswick, David W. Brown, Anthony D R Angell, Savvas Kleanthous
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:3037-3040
Heteroalicyclic carboxamidines were synthesised and evaluated as inhibitors of nitric oxide synthases. (2R)-2-Pyrrolidinecarboxamidine, in particular, was shown to be a highly potent in vitro (IC50 = 0.12 μM) and selective iNOS inhibitor (>100-fold
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::773439dbec64b955efa494d151e9cf88
https://doi.org/10.1016/j.bmcl.2011.03.038
https://doi.org/10.1016/j.bmcl.2011.03.038
Autor:
Linda Irvine, Kirsty Forsyth, Miriam Crowe, Donald Maciver, Christine Owen, Jacqueline Pentland, Mike Walsh
Publikováno v:
Disability and rehabilitation. 38(3)
The National Health Service in Scotland published a best practice framework to support occupational therapists and physiotherapists to deliver effective services for children with developmental co-ordination disorder (DCD); however, adherence is vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fbb2bfd10de14e6b59f94c648559189
https://pubmed.ncbi.nlm.nih.gov/25901454
https://pubmed.ncbi.nlm.nih.gov/25901454
Autor:
Chun-wa Chung, Mélanie Barnathan, Phillip Jeffrey, Nicholas Smithers, Romain Luc Marie Gosmini, Olivier Pineau, Jacqueline Elizabeth Mordaunt, Jason Witherington, Alain Claude-Marie Daugan, Myriam Ajakane, Leanne Cutler, Paul Bamborough, Nigel J. Parr, Jean-Marie Brusq, Iain Uings, Andrea C. Haynes, Antonia J. Lewis, Jérôme Toum, Rab K. Prinjha, Olivier Mirguet, Catherine A. Clément, Edwige Nicodeme, Miriam Crowe, Grimes Richard Martin
Publikováno v:
Journal of medicinal chemistry. 56(19)
The bromo and extra C-terminal domain (BET) family of bromodomains are involved in binding epigenetic marks on histone proteins, more specifically acetylated lysine residues. This paper describes the discovery and structure–activity relationships (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b0781caa707d63e5ebf47768737d8a9
https://pubmed.ncbi.nlm.nih.gov/24107192
https://pubmed.ncbi.nlm.nih.gov/24107192
Autor:
Matthew Campbell, Ping Zhou, Robert J. Young, Weston Helen Elisabeth, Savvas Kleanthous, David W. Brown, Champa Patel, Satish Dayal, Shah Gita Punjabhai, Alan D. Borthwick, N. Paul King, Cynthia L. Burns-Kurtis, Stefan Senger, Hawa Diallo, Máire A. Convery, Nigel S. Watson, Paul W. Smith, Henry Anderson Kelly, Miriam Crowe, Chuen Chan, Anthony J. Pateman, Jackie E. Mordaunt, Andrew M. Mason
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(23)
Structure-based drug design was exploited in the synthesis of 3-(6-chloronaphth-2-ylsulfonyl)aminopyrrolidin-2-one-based factor Xa (fXa) inhibitors, incorporating an alanylamide P4 group with acyclic tertiary amide termini. Optimized hydrophobic cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3b9901e5afa05ffed0024b5adc2fb9
https://pubmed.ncbi.nlm.nih.gov/16982190
https://pubmed.ncbi.nlm.nih.gov/16982190