Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Miriam Celine Krekeler"'
Autor:
Philipp Bengel, Nataliya Dybkova, Petros Tirilomis, Shakil Ahmad, Nico Hartmann, Belal A. Mohamed, Miriam Celine Krekeler, Wiebke Maurer, Steffen Pabel, Maximilian Trum, Julian Mustroph, Jan Gummert, Hendrik Milting, Stefan Wagner, Senka Ljubojevic-Holzer, Karl Toischer, Lars S. Maier, Gerd Hasenfuss, Katrin Streckfuss-Bömeke, Samuel Sossalla
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
In heart failure, increased CaMKII activity is decisively involved in arrhythmia formation. Here, the authors introduce the neuronal sodium channel NaV1.8 as a CaMKII downstream target as its specific knock-out reduces arrhythmias and improves surviv
Externí odkaz:
https://doaj.org/article/ba56cc69ae1140aebe506e2a3f9b30eb
Autor:
Stefan Wagner, Wiebke Maurer, Hendrik Milting, Nico Hartmann, Katrin Streckfuss-Bömeke, Julian Mustroph, Belal A. Mohamed, Maximilian Trum, P Tirilomis, Lars S. Maier, Karl Toischer, Miriam Celine Krekeler, Jan Gummert, Senka Ljubojevic-Holzer, Steffen Pabel, Gerd Hasenfuss, Samuel Sossalla, Nataliya Dybkova, Shakil Ahmad, Philipp Bengel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
An interplay between Ca2+/calmodulin-dependent protein kinase IIδc (CaMKIIδc) and late Na+ current (INaL) is known to induce arrhythmias in the failing heart. Here, we elucidate the role of the sodium channel isoform NaV1.8 for CaMKIIδc-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10a8415f93078d89d557c95a0d79a40d
