Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Miriam B. F. Werneck"'
Autor:
Vanessa Neitzke-Montinelli, Carolina Calôba, Guilherme Melo, Bianca B. Frade, Enzo Caramez, Luciano Mazzoccoli, André N. A. Gonçalves, Helder I. Nakaya, Renata M. Pereira, Miriam B. F. Werneck, João P. B. Viola
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Long-term immunological protection relies on the differentiation and maintenance of memory lymphocytes. Since the knowledge of memory generation has been centered on in vivo models of infection, there are obstacles to deep molecular analysis of diffe
Externí odkaz:
https://doaj.org/article/618a0bd1306c4679bcb6a137e9955e5c
Autor:
Vanessa Neitzke-Montinelli, Carolina Calôba, Guilherme Melo, Bianca B. Frade, Enzo Caramez, Luciano Mazzoccoli, André N. A. Gonçalves, Helder I. Nakaya, Renata M. Pereira, Miriam B. F. Werneck, João P. B. Viola
Publikováno v:
Frontiers in immunology. 13
Long-term immunological protection relies on the differentiation and maintenance of memory lymphocytes. Since the knowledge of memory generation has been centered on in vivo models of infection, there are obstacles to deep molecular analysis of diffe
Autor:
João P. B. Viola, Patrícia T. Bozza, Narayana P. B. Fazolini, André L S Cruz, Clarissa M. Maya-Monteiro, Miriam B. F. Werneck
Publikováno v:
Cell Cycle
Accumulating evidence suggests that obesity and enhanced inflammatory reactions are predisposing conditions for developing colon cancer. Obesity is associated with high levels of circulating leptin. Leptin is an adipocytokine that is secreted by adip
Publikováno v:
Cell Cycle. 11:3997-4008
Chronic inflammation is a risk factor for the development of colon cancer, providing genotoxic insults, growth and pro-angiogenic factors that can promote tumorigenesis and tumor growth. Immunomodulatory agents can interfere with the inflammation tha
Autor:
Miriam B. F. Werneck
Publikováno v:
Frontiers in Bioscience. :1518-1538
It has been recently shown that within heterogeneous tumor masses a small population of less differentiated transformed cells has the ability to self-renew and regenerate the bulk of the tumor. Their similarities with normal stem cells in terms of ge
Autor:
Hye-Jung Kim, Phuong L. Nguyen, Courtney G. Sansam, Boris G. Wilson, Charles W. M. Roberts, Jonathan W. Wischhusen, Xi Wang, Christopher S. Thom, Miriam B. F. Werneck, Michael J. Kluk, Julia A. Evans, Jonathan L. Jesneck, Harvey Cantor
Publikováno v:
Journal of Clinical Investigation. 121:3834-3845
A fundamental goal in cancer research is the identification of the cell types and signaling pathways capable of initiating and sustaining tumor growth, as this has the potential to reveal therapeutic targets. Stem and progenitor cells have been impli
Publikováno v:
Cancer Immunology, Immunotherapy. 60:537-546
Members of the nuclear factor of activated T cell (NFAT) family of transcription factors were originally described in T lymphocytes but later shown to be expressed in several immune and non-immune cell types. NFAT proteins can modulate cellular trans
Autor:
David L. Stachura, David Traver, Keir M. Balla, Geanncarlo Lugo-Villarino, Miriam B. F. Werneck, Karina Bañuelos
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2010, 107 (36), pp.15850-15855. ⟨10.1073/pnas.1000494107⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2010, 107 (36), pp.15850-15855. ⟨10.1073/pnas.1000494107⟩
In mammals, dendritic cells (DCs) form the key link between the innate and adaptive immune systems. DCs act as immune sentries in various tissues and, upon encountering pathogen, engulf and traffic foreign antigen to secondary lymphoid tissues, stimu
Autor:
Benjamin H. Lee, Sandra A. Moore, Harvey Cantor, Severine Le Bras, Michael G. Kharas, Melanie G. Cornejo, Scott J. Rodig, Jean-Philippe Merlio, Marie Beylot-Barry, Jon C. Aster, Thomas Mercher, Miriam B. F. Werneck, Brian Ball, D. Gary Gilliland
Publikováno v:
Blood. 113:2746-2754
The tyrosine kinase JAK3 plays a well-established role during normal lymphocyte development and is constitutively phosphorylated in several lymphoid malignancies. However, its contribution to lymphomagenesis remains elusive. In this study, we used th
Autor:
Harvey Cantor, Jing Bu, Laurie H. Glimcher, Miriam B. F. Werneck, Linrong Lu, Koichi Kobayashi, Mari L. Shinohara
Publikováno v:
Nature Immunology. 7:498-506
The observation that the T-bet transcription factor allows tissue-specific upregulation of intracellular osteopontin (Opn-i) in plasmacytoid dendritic cells (pDCs) suggests that Opn might contribute to the expression of interferon-alpha (IFN-alpha) i