Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Miriam Amiram"'
Publikováno v:
Advanced NanoBiomed Research, Vol 2, Iss 6, Pp n/a-n/a (2022)
Inspired by nature, scientists have harnessed the natural protein translation machinery to produce intricate and precise protein‐based polymers (PBPs)—composed of natural amino acid monomers and assembled on the nano‐to‐macro scale—for drug
Externí odkaz:
https://doaj.org/article/4182a5c680bc4b698e9a7bfde6ad01c3
Autor:
Osher Gueta, Ortal Sheinenzon, Rotem Azulay, Hadas Shalit, Daniela S. Strugach, Dagan Hadar, Sigal Gelkop, Anat Milo, Miriam Amiram
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
The incorporation of non-canonical amino acids (ncAAs) using engineered aminoacyl-tRNA synthetases (aaRSs) has emerged as a powerful methodology to expand the chemical repertoire of proteins. However, the low efficiencies of typical aaRS variants lim
Externí odkaz:
https://doaj.org/article/1adc16c0f6d54dbe995a6879aa603c70
Autor:
Rey W. Martin, Benjamin J. Des Soye, Yong-Chan Kwon, Jennifer Kay, Roderick G. Davis, Paul M. Thomas, Natalia I. Majewska, Cindy X. Chen, Ryan D. Marcum, Mary Grace Weiss, Ashleigh E. Stoddart, Miriam Amiram, Arnaz K. Ranji Charna, Jaymin R. Patel, Farren J. Isaacs, Neil L. Kelleher, Seok Hoon Hong, Michael C. Jewett
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Cell-free protein synthesis allows for producing proteins without the need of a host organism, thus sparing the researcher experimental hassle. Here, the authors developed a cell-free synthesis method that enables incorporating non-standard amino aci
Externí odkaz:
https://doaj.org/article/48f02766cbcf45fab8fa2795bb729a58
Autor:
Osher Gueta, Miriam Amiram
Publikováno v:
Advanced drug delivery reviews. 190
Expanding the chemical repertoire of natural and artificial protein-based polymers (PBPs) can enable the production of sequence-defined, yet chemically diverse, biopolymers with customized or new properties that cannot be accessed in PBPs composed of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a9314d3f3da82cd47a481388cf2f2c
https://pubmed.ncbi.nlm.nih.gov/36030987
https://pubmed.ncbi.nlm.nih.gov/36030987
Autor:
Koen Vanderschuren, Pol Arranz-Gibert, Minsoo Khang, Dagan Hadar, Alice Gaudin, Fan Yang, Ewa Folta-Stogniew, W. Mark Saltzman, Miriam Amiram, Farren J. Isaacs
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Functionalization of proteins and biopolymers with chemical modifications can be utilized to alter their chemical and biophysical properties. In contrast to traditional chemical functionalization strategies, the use of nonstandard amino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b97f48d80159318de5d45205bfc322
https://pubmed.ncbi.nlm.nih.gov/35046019
https://pubmed.ncbi.nlm.nih.gov/35046019
Publikováno v:
Israel Journal of Chemistry. 60:1118-1128
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdccb9b6f264b1c9a2b6c99f86441c23
https://doi.org/10.1002/ijch.201900043
https://doi.org/10.1002/ijch.201900043
Publikováno v:
Chembiochem : a European journal of chemical biology. 22(8)
Site-specific incorporation of unnatural amino acids (uAAs) bearing a bioorthogonal group has enabled the attachment - typically at a single site or at a few sites per protein - of chemical groups at precise locations for protein and biomaterial labe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df7085da04d20230bd0d26b8c214ded
https://pubmed.ncbi.nlm.nih.gov/33350556
https://pubmed.ncbi.nlm.nih.gov/33350556
Autor:
Jaymin R. Patel, Benjamin J. Des Soye, Roderick G. Davis, Ashleigh E. Stoddart, Ryan D. Marcum, Neil L. Kelleher, Arnaz K. Ranji Charna, Natalia I. Majewska, Rey W. Martin, Michael C. Jewett, Cindy X. Chen, Paul M. Thomas, Miriam Amiram, Yong-Chan Kwon, Farren J. Isaacs, Jennifer E. Kay, Seok Hoon Hong, Mary Grace Weiss
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Nature Communications
Nature Communications
Cell-free protein synthesis has emerged as a powerful approach for expanding the range of genetically encoded chemistry into proteins. Unfortunately, efforts to site-specifically incorporate multiple non-canonical amino acids into proteins using crud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ad52f9074aa4ebeb5d5a7d0dba8613
https://doi.org/10.1038/s41467-018-03469-5
https://doi.org/10.1038/s41467-018-03469-5
Autor:
Alexis J. Rovner, Jaymin R. Patel, Miriam Amiram, Adrian D. Haimovich, Zhe Li, Jesse Rinehart, Michael W. Grome, Spencer R. Katz, Ryan R. Gallagher, Farren J. Isaacs, Brandon M. Gassaway
Publikováno v:
Nature
Construction of a series of genomically recoded organisms whose growth is restricted by the expression of essential genes dependent on exogenously supplied synthetic amino acids introduces novel orthogonal barriers between these engineered organisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c76246e8b8011c0f09b7e9a32c9ac1ba
http://europepmc.org/articles/PMC4590768
http://europepmc.org/articles/PMC4590768
Autor:
Ashutosh Chilkoti, Joseph J. Bellucci, Dewey G. McCafferty, Miriam Amiram, Jayanta Bhattacharyya
Publikováno v:
Angewandte Chemie. 125:3791-3796
Applied in tandem, elastin-like polypeptides (ELPs) and the sortase A (SrtA) transpeptidase from Staphylococcus aureus provide a general method for chromatography-free purification of tag-free recombinant proteins and optional, site-specific and homo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8faecfeee364593e19c48bafc60d40f5
https://doi.org/10.1002/ange.201208292
https://doi.org/10.1002/ange.201208292