Citizen-science based study of the oral microbiome in Cystic fibrosis and matched controls reveals major differences in diversity and abundance of bacterial and fungal species

Autor: Jesse R. Willis, Ester Saus, Susana Iraola-Guzmán, Elena Cabello-Yeves, Ewa Ksiezopolska, Luca Cozzuto, Luis A. Bejarano, Nuria Andreu-Somavilla, Miriam Alloza-Trabado, Andrea Blanco, Anna Puig-Sola, Elisabetta Broglio, Carlo Carolis, Julia Ponomarenko, Jochen Hecht, Toni Gabaldón

Publikováno v: Journal of Oral Microbiology, Vol 13, Iss 1 (2021)

Introduction: Cystic fibrosis (CF) is an autosomal genetic disease, associated with the production of excessively thick mucosa and with life-threatening chronic lung infections. The microbiota of the oral cavity can act as a reservoir or as a barrier

Externí odkaz: https://doaj.org/article/957049651e4f462f95752a93cd98724f

Citizen science charts two major 'stomatotypes' in the oral microbiome of adolescents and reveals links with habits and drinking water composition

Autor: Jesse R. Willis, Pedro González-Torres, Alexandros A. Pittis, Luis A. Bejarano, Luca Cozzuto, Nuria Andreu-Somavilla, Miriam Alloza-Trabado, Antonia Valentín, Ewa Ksiezopolska, Carlos Company, Harris Onywera, Magda Montfort, Antonio Hermoso, Susana Iraola-Guzmán, Ester Saus, Annick Labeeuw, Carlo Carolis, Jochen Hecht, Julia Ponomarenko, Toni Gabaldón

Publikováno v: Microbiome, Vol 6, Iss 1, Pp 1-17 (2018)

Abstract Background The oral cavity comprises a rich and diverse microbiome, which plays important roles in health and disease. Previous studies have mostly focused on adult populations or in very young children, whereas the adolescent oral microbiom

Externí odkaz: https://doaj.org/article/4c088ea97cd448e8b1581a419ec95f90

Oral microbiome in down syndrome and its implications on oral health

Autor: Carlo Carolis, Julia Ponomarenko, Nuria Andreu-Somavilla, Elisabetta Broglio, Miriam Alloza-Trabado, Luis A. Bejarano, Susana Iraola-Guzmán, Anna Puig-Sola, Toni Gabaldón, Andrea Blanco, Ester Saus, Ewa Ksiezopolska, Jochen Hecht, Luca Cozzuto, Jesse R. Willis

Publikováno v: UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Journal of Oral Microbiology, Vol 13, Iss 1 (2021)
Journal of Oral Microbiology
article-version (VoR) Version of Record

Introduction: The oral cavity harbors an abundant and diverse microbial community (i.e. the microbiome), whose composition and roles in health and disease have been the focus of intense research. Down syndrome (DS) is associated with particular chara

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49981271e4074c79e6bb949a53143ff1

ADP-ribose-derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling

Autor: Miriam A. Trabado, Maria J. Macias, Jofre Font-Mateu, Baldo Oliva, Michael Wierer, Oscar Yanes, Roni H. G. Wright, Sara Samino, Constanze Schelhorn, Andy Pohl, Daniel Soronellas, Ana Silvina Nacht, Jaume Bonet, Guillermo P. Vicent, Antonios Lioutas, Carlo Carolis, Miguel Beato, François Le Dily

Publikováno v: Science

A nuclear power source in the cell DNA is packaged onto nucleosomes, the principal component of chromatin. This chromatin must be remodeled to allow gene transcription, DNA replication, and DNA repair machineries access to the enclosed DNA. Chromatin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dcf7ed82a56524e2baa8820c1275dda
https://pubmed.ncbi.nlm.nih.gov/31175344