Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Miriam, Wittmann"'
Autor:
Miriam Wittmann, Isabelle L Smith, Sarah Tess Brown, Anna Berekméri, Armando Vargas-Palacios, Lesley Sunderland, Amy Barker, Fiona Cowdell, Steven Ersser, Rachael Gilberts, Cathy Green, Philip Hampton, Catherine Smith, Jane Nixon
Publikováno v:
Health Technology Assessment, Vol 28, Iss 59 (2024)
Background Hand eczema is common and a cause of morbidity and occupational disability. When education, irritant/contact allergen avoidance, moisturisation and topical corticosteroids are insufficient to control chronic hand eczema, ultraviolet therap
Externí odkaz:
https://doaj.org/article/0ae46cf2c4474a0dbf7268e95efa70d5
Autor:
Steven J Edwards, Charlotta Karner, Tracey Jhita, Samantha Barton, Gemma Marceniuk, Zenas Z N Yiu, Miriam Wittmann
Publikováno v:
Health Technology Assessment, Vol 28, Iss 04 (2024)
Background Atopic dermatitis is a chronic relapsing inflammatory skin condition. One of the most common skin disorders in children, atopic dermatitis typically manifests before the age of 5 years, but it can develop at any age. Atopic dermatitis is c
Externí odkaz:
https://doaj.org/article/1274ca3c50664411bbcdcb771f3d276b
Autor:
Berenice Fischer, Tanja Kübelbeck, Antonia Kolb, Julia Ringen, Ari Waisman, Miriam Wittmann, Susanne Karbach, Stephan Marcus Kölsch, Daniela Kramer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Plaque psoriasis is an autoinflammatory and autoimmune skin disease, affecting 1-3% of the population worldwide. Previously, high levels of IL-36 family cytokines were found in psoriatic skin lesions, thereby contributing to keratinocyte hyperprolife
Externí odkaz:
https://doaj.org/article/c09af3e842354597b44bb3049b851775
Autor:
Neil Solomons, Ian N Bruce, Paul Emery, Caroline Gordon, Edward Vital, David Jayne, David Isenberg, Neil McHugh, Miriam Wittmann, Stephen Young, John Reynolds, Niels Peek, Mark Lunt, Li Su, Sean Gavan, Katherine Payne, Michael Ehrenstein, Vern Farewell, Timothy Vyse, Marina Botto, David Lester Morris, D D’Cruz, Nophar Geifman, Angela Midgley, Matt Truman, Stephen McDonald, Sean Yiu, Laura Lisk, Gillian Armitt, Jennifer Prattley, Narges Azadbakht, Angela Papazian, Helen Le Sueur, Carmen Farrelly, Clare Richardson, Zunnaira Shabbir, Lauren Hewitt, Matthew Pickering, Elizabeth Lightstone, Alyssa Gilmore, Michael Beresford, Christian Hedrich, Jenna Gritzfeld, Mariea Parvaz, Jane Dunnage, Jane Batchelor, E Holland, Pauline Upsall
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss 1 (2022)
Objectives To identify predictors of overall lupus and lupus nephritis (LN) responses in patients with LN.Methods Data from the Aspreva Lupus Management Study (ALMS) trial cohort was used to identify baseline predictors of response at 6 months. Endpo
Externí odkaz:
https://doaj.org/article/e8abdf0db45c48c2bc679943283668a8
Autor:
Antonios Psarras, Adewonuola Alase, Agne Antanaviciute, Ian M. Carr, Md Yuzaiful Md Yusof, Miriam Wittmann, Paul Emery, George C. Tsokos, Edward M. Vital
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Type I interferon drives autoimmune pathology in SLE and has been assumed to come predominantly from plasmacytoid dendritic cells (pDCs). Here, the authors show that prior to the onset of SLE, pDCs lose multiple immunogenic functions and, instead, no
Externí odkaz:
https://doaj.org/article/bbb2318833484129bd8e0fdec78640c3
Autor:
Catherine Smith, Miriam Wittmann, Fiona Cowdell, Sarah Brown, Catherine Reynolds, Catherine Fernandez, Sandy Tubeuf, Jane Nixon, Rachael Gilberts, Mark Goodfield, Isabelle L Smith, John T Lear, Lesley Sunderland, Cathy Green, Philip Hampton, Amy Barker, Armando Vargas-Palacios
Publikováno v:
BMJ Open, Vol 12, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/6a776fbdac6143feb92fe5508b107b42
Autor:
Tom Macleod, Anna Berekmeri, Charlie Bridgewood, Martin Stacey, Dennis McGonagle, Miriam Wittmann
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The skin barrier would not function without IL-1 family members, but their physiological role in the immunological aspects of skin barrier function are often overlooked. This review summarises the role of IL-1 family cytokines (IL-1α, IL-1β, IL-1Ra
Externí odkaz:
https://doaj.org/article/81b21c05d1f047d4bba0270b9bf448e9
Autor:
John A Reynolds, Edward Vital, Miriam Wittmann, Zoe Wigston, Yuzaiful Yusof, Agata Burska, Adewonuola Alase, Lucy M Carter, Antony Psarras
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/89abb2bf4bcf4ab1b9363536eccd239c
Autor:
Thomas Macleod, Joseph S. Ainscough, Christina Hesse, Sebastian Konzok, Armin Braun, Anna-Lena Buhl, Joerg Wenzel, Paul Bowyer, Yutaka Terao, Sarah Herrick, Miriam Wittmann, Martin Stacey
Publikováno v:
Cell Reports, Vol 33, Iss 11, Pp 108515- (2020)
Summary: Epithelial tissues represent vital interfaces between organisms and their environment. As they are constantly exposed to harmful pathogens, innocuous commensals, and environmental microbes, it is essential they sense and elicit appropriate r
Externí odkaz:
https://doaj.org/article/83bec1d408764455abe14e907b7e24a4
Autor:
Charlie Bridgewood, Miriam Wittmann, Tom Macleod, Abdulla Watad, Darren Newton, Kanchan Bhan, Howard Amital, Giovanni Damiani, Sami Giryes, Nicola Luigi Bragazzi, Dennis McGonagle
Publikováno v:
Journal of Investigative Dermatology. 142:2660-2667
Dupilumab, an IL-4/IL-13 receptor blocker, has been linked to emergent seronegative inflammatory arthritis and psoriasis that form part of the spondyloarthropathy spectrum. We systematically investigated patterns of immune disorders, including predom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73544235f8dfb519543fb697e5e5224c
https://doi.org/10.1016/j.jid.2022.03.013
https://doi.org/10.1016/j.jid.2022.03.013