Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Miriam, Sciaccaluga"'
Autor:
Daniel F. Burgos, Miriam Sciaccaluga, Carolyn A. Worby, Luis Zafra-Puerta, Nerea Iglesias-Cabeza, Gema Sánchez-Martín, Paolo Prontera, Cinzia Costa, José M. Serratosa, Marina P. Sánchez
Publikováno v:
Neurobiology of Disease, Vol 181, Iss , Pp 106119- (2023)
Lafora disease is a rare recessive form of progressive myoclonic epilepsy, usually diagnosed during adolescence. Patients present with myoclonus, neurological deterioration, and generalized tonic-clonic, myoclonic, or absence seizures. Symptoms worse
Externí odkaz:
https://doaj.org/article/1ed534af11534c5980ce7b80c1642e34
Autor:
Petra Mazzocchetti, Andrea Mancini, Miriam Sciaccaluga, Alfredo Megaro, Laura Bellingacci, Massimiliano Di Filippo, Elena Nardi Cesarini, Michele Romoli, Nicolò Carrano, Fabrizio Gardoni, Alessandro Tozzi, Paolo Calabresi, Cinzia Costa
Publikováno v:
Neurobiology of Disease, Vol 140, Iss , Pp 104848- (2020)
Energy depletion caused by ischemic brain insults may result in persistent neuronal depolarization accompanied by hyper-stimulation of ionotropic glutamate receptors and excitotoxic phenomena, possibly leading to cell death. The use of glutamate rece
Externí odkaz:
https://doaj.org/article/7096c9b9106e4383afc1ad4813c54656
Autor:
Andrea Mancini, Petra Mazzocchetti, Miriam Sciaccaluga, Alfredo Megaro, Laura Bellingacci, Dayne A. Beccano-Kelly, Massimiliano Di Filippo, Alessandro Tozzi, Paolo Calabresi
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
The pathogenesis of Parkinson’s disease (PD) is thought to rely on a complex interaction between the patient’s genetic background and a variety of largely unknown environmental factors. In this scenario, the investigation of the genetic bases und
Externí odkaz:
https://doaj.org/article/89787d5dd6e148149dc72a01621d0d57
Autor:
Maria Di Bari, Vanessa Tombolillo, Francesco Alessandrini, Claudia Guerriero, Mario Fiore, Italia Anna Asteriti, Emilia Castigli, Miriam Sciaccaluga, Giulia Guarguaglini, Francesca Degrassi, Ada Maria Tata
Publikováno v:
Cells, Vol 10, Iss 7, p 1727 (2021)
Background: Glioblastoma multiforme (GBM) is characterized by several genetic abnormalities, leading to cell cycle deregulation and abnormal mitosis caused by a defective checkpoint. We previously demonstrated that arecaidine propargyl ester (APE), a
Externí odkaz:
https://doaj.org/article/4efaad0827cb4138b8b9aaf9c2272d2e
Abstract: Despite the wide range of compounds currently available to treat epilepsy, there is still no drug that directly tackles the physiopathological mechanisms underlying its development. Indeed, antiseizure medications attempt to prevent seizure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b43f801c88de807e61b08eb1f462770
https://hdl.handle.net/11391/1549989
https://hdl.handle.net/11391/1549989
Autor:
Flavia Trettel, Cristina Roseti, Rosalba Carrozzo, Teresa Rizza, Susanna Cogo, Anna Rita Bentivoglio, Claudia Carducci, Cristina Limatola, Alice Traversa, Gianfranco Bocchinfuso, Martina Venditti, Laura Civiero, Michela Di Nottia, Viviana Caputo, Eleonora Palma, Miriam Sciaccaluga, Ambra Lanzo, Maria Paglione, Luca Pannone, Manju A. Kurian, Serena Galosi, Simone Martinelli, Vincenzo Leuzzi, Lorenzo Stella, A Farrotti, Sergio Fucile, Laura Bernardini, Viviana Cordeddu, Joanne Ng, Marco Tartaglia, Elia Di Schiavi, Elisa Greggio, Andrea Ciolfi
Publikováno v:
Parkinsonism & related disorders 72 (2020): 75–79. doi:10.1016/j.parkreldis.2020.02.003
info:cnr-pdr/source/autori:Martinelli, Simone; Cordeddu, Viviana; Galosi, Serena; Lanzo, Ambra; Palma, Eleonora; Pannone, Luca; Ciolfi, Andrea; Di Nottia, Michela; Rizza, Teresa; Bocchinfuso, Gianfranco; Traversa, Alice; Caputo, Viviana; Farrotti, Andrea; Carducci, Claudia; Bernardini, Laura; Cogo, Susanna; Paglione, Maria; Venditti, Martina; Bentivoglio, Annarita; Ng, Joanne; Kurian, Manju A.; Civiero, Laura; Greggio, Elisa; Stella, Lorenzo; Trettel, Flavia; Sciaccaluga, Miriam; Roseti, Cristina; Carrozzo, Rosalba; Fucile, Sergio; Limatola, Cristina; Di Schiavi, Elia; Tartaglia, Marco; Leuzzi, Vincenzo/titolo:Co-occurring WARS2 and CHRNA6 mutations in a child with a severe form of infantile parkinsonism/doi:10.1016%2Fj.parkreldis.2020.02.003/rivista:Parkinsonism & related disorders/anno:2020/pagina_da:75/pagina_a:79/intervallo_pagine:75–79/volume:72
info:cnr-pdr/source/autori:Martinelli, Simone; Cordeddu, Viviana; Galosi, Serena; Lanzo, Ambra; Palma, Eleonora; Pannone, Luca; Ciolfi, Andrea; Di Nottia, Michela; Rizza, Teresa; Bocchinfuso, Gianfranco; Traversa, Alice; Caputo, Viviana; Farrotti, Andrea; Carducci, Claudia; Bernardini, Laura; Cogo, Susanna; Paglione, Maria; Venditti, Martina; Bentivoglio, Annarita; Ng, Joanne; Kurian, Manju A.; Civiero, Laura; Greggio, Elisa; Stella, Lorenzo; Trettel, Flavia; Sciaccaluga, Miriam; Roseti, Cristina; Carrozzo, Rosalba; Fucile, Sergio; Limatola, Cristina; Di Schiavi, Elia; Tartaglia, Marco; Leuzzi, Vincenzo/titolo:Co-occurring WARS2 and CHRNA6 mutations in a child with a severe form of infantile parkinsonism/doi:10.1016%2Fj.parkreldis.2020.02.003/rivista:Parkinsonism & related disorders/anno:2020/pagina_da:75/pagina_a:79/intervallo_pagine:75–79/volume:72
Objective To investigate the molecular cause(s) underlying a severe form of infantile-onset parkinsonism and characterize functionally the identified variants. Methods A trio-based whole exome sequencing (WES) approach was used to identify the candid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e750dcab6b5e7a1b6ab8d5c5c98db0a
https://doi.org/10.1016/j.parkreldis.2020.02.003
https://doi.org/10.1016/j.parkreldis.2020.02.003
Autor:
Valeria Calabrese, Barbara Picconi, Nicolas Heck, Federica Campanelli, Giuseppina Natale, Gioia Marino, Miriam Sciaccaluga, Veronica Ghiglieri, Alessandro Tozzi, Estelle Anceaume, Emeline Cuoc, Jocelyne Caboche, François Conquet, Paolo Calabresi, Delphine Charvin
Publikováno v:
Neuropharmacology. 218
By decreasing glutamate transmission, mGlu4 receptor positive allosteric modulators (mGlu4-PAM), in combination with levodopa (l-DOPA) may restore the synergy between glutamatergic and dopaminergic transmissions, thus maximizing the improvement of mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8db8e30cb121cb91d620ded9516613e6
https://pubmed.ncbi.nlm.nih.gov/35940348
https://pubmed.ncbi.nlm.nih.gov/35940348
Publikováno v:
Current neuropharmacology. 20(11)
Abstract: The literature on epileptic seizures in Alzheimer's disease has significantly increased over the past decades. Remarkably, several studies suggest a bi-directional link between these two common neurological diseases, with either condition c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7fb493a85a8f6faed07aebc5acbd38
https://pubmed.ncbi.nlm.nih.gov/35524669
https://pubmed.ncbi.nlm.nih.gov/35524669
Striatal spreading depolarization: Possible implication in levodopa‐induced dyskinetic‐like behavior
Autor:
Cinzia Costa, Michela Tantucci, Petra Mazzocchetti, Alessandro Tozzi, Antonio de Iure, Daniela Punzo, Goichi Beck, Veronica Ghiglieri, Ana Quiroga Varela, Antonella Cardinale, Miriam Sciaccaluga, Francesco Napolitano, Alessandro Usiello, Stella M. Papa, Paolo Calabresi, Valentina Durante, Andrea Mancini, Barbara Picconi, Alfredo Megaro
Publikováno v:
Mov Disord
Objective Spreading depolarization (SD) is a transient self-propagating wave of neuronal and glial depolarization coupled with large membrane ionic changes and a subsequent depression of neuronal activity. Spreading depolarization in the cortex is im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ef2776848e5c32a182e86b8a3f5de31
https://doi.org/10.1002/mds.27632
https://doi.org/10.1002/mds.27632
Autor:
Massimiliano Di Filippo, Andrea Mancini, Laura Bellingacci, Lorenzo Gaetani, Petra Mazzocchetti, Teresa Zelante, Livia La Barbera, Antonella De Luca, Michela Tantucci, Alessandro Tozzi, Valentina Durante, Miriam Sciaccaluga, Alfredo Megaro, Davide Chiasserini, Nicola Salvadori, Viviana Lisetti, Emilio Portaccio, Cinzia Costa, Paola Sarchielli, Maria Pia Amato, Lucilla Parnetti, Maria Teresa Viscomi, Luigina Romani, Paolo Calabresi
Cognitive impairment (CI) is a disabling concomitant of multiple sclerosis (MS) with a complex and controversial pathogenesis. The cytokine interleukin-17A (IL-17A) is involved in the immune pathogenesis of MS, but its possible effects on synaptic fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::350e0570178a4278a38ba221e16a2872
http://hdl.handle.net/10807/198244
http://hdl.handle.net/10807/198244