Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Miriam, Kretschmer"'
Autor:
Mahshid Gazorpak, Karina M. Hugentobler, Dominique Paul, Pierre-Luc Germain, Miriam Kretschmer, Iryna Ivanova, Selina Frei, Kei Mathis, Remo Rudolf, Sergio Mompart Barrenechea, Vincent Fischer, Xiaohan Xue, Aleksandra L. Ptaszek, Julian Holzinger, Mattia Privitera, Andreas Hierlemann, Onno C. Meijer, Robert Konrat, Erick M. Carreira, Johannes Bohacek, Katharina Gapp
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Counteracting the overactivation of glucocorticoid receptors (GR) is an important therapeutic goal in stress-related psychiatry and beyond. The only clinically approved GR antagonist lacks selectivity and induces unwanted side effects. To co
Externí odkaz:
https://doaj.org/article/a28a8f76999f4d2694653264846e8de2
Autor:
Vincent Fischer, Miriam Kretschmer, Pierre-Luc Germain, Jasmine Kaur, Sergio Mompart-Barrenechea, Pawel Pelczar, David Schürmann, Primo Schär, Katharina Gapp
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Dexamethasone is a stress hormone receptor agonist used widely in clinics. We and others previously showed that paternal administration of dexamethasone in mice affects the phenotype of their offspring. The substrate of intergenerational tra
Externí odkaz:
https://doaj.org/article/5198a92cd6a1478f8414a17dd3b16284
Publikováno v:
Biomolecules, Vol 13, Iss 12, p 1750 (2023)
Multiple lines of evidence suggest that paternal psychological stress contributes to an increased prevalence of neuropsychiatric and metabolic diseases in the progeny. While altered paternal care certainly plays a role in such transmitted disease ris
Externí odkaz:
https://doaj.org/article/80b2092138764605a4f3b5a46c271964
Autor:
Miriam, Kretschmer, Katharina, Gapp
Publikováno v:
Environmental epigenetics. 8(1)
The inheritance of neurophysiologic and neuropsychologic complex diseases can only partly be explained by the Mendelian concept of genetic inheritance. Previous research showed that both psychological disorders like post-traumatic stress disorder and