Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Miria de Oliveira Barbosa"'
Autor:
Horison Lopes de Oliveira, Wanderson dos Santos Sousa, Luiz Filipe Alves Cordeiro, Miria de Oliveira Barbosa
Publikováno v:
Revista Brasileira de Gestão Ambiental e Sustentabilidade. 9:899-914
O avanço da Ciência, principalmente no que se relaciona com os meios para cuidados com a saúde, propiciou aumento na descoberta e produção de medicamentos que tratam a maioria dos tipos de doenças. Em contrapartida, o inevitável aumento no uso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63d07e7dff4de95e84116a5c0241a046
https://doi.org/10.21438/rbgas(2022)092224
https://doi.org/10.21438/rbgas(2022)092224
Autor:
Sheilla Andrade de Oliveira, Edna de Farias Santiago, Ana Cristina Lima Leite, Paulo André Teixeira de Moraes Gomes, Carlos André Laranjeira Miranda Filho, Fábio André Brayner, Fabiano Amaro de Sousa, Juliana Maria da Conceição, Luiz Carlos Alves, Gevanio Bezerra de Oliveira Filho, Miria de Oliveira Barbosa, Arsênio Rodrigues Oliveira
Publikováno v:
Parasitology Research. 117:2105-2115
Phthalimide, 1,3-thiazole, and thiazolidinone cores are considered privileged scaffolds and represent an attractive starting point to design new bioactive compounds for neglected tropical disease (NTD). Schistosomiasis is a NTD, caused by Schistosoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d30871bff8bd1fc60a16218c7759fd
https://doi.org/10.1007/s00436-018-5897-4
https://doi.org/10.1007/s00436-018-5897-4
Autor:
Miria de Oliveira Barbosa, Teresinha Gonçalves da Silva, Ana Cristina Lima Leite, Temístocles Italo de Santana, Paulo André Teixeira de Moraes Gomes, Anne Cecília Nascimento da Cruz
Publikováno v:
European Journal of Medicinal Chemistry. 144:874-886
Thiazole derivatives are recognized to possess various biological activities as antiparasitic, antifungal, antimicrobial and antiproliferative. The present work reports the synthesis of 22 new substances belonging to two classes of compounds: thiosem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acc9fda434c7f5c642b028eb447714fb
https://doi.org/10.1016/j.ejmech.2017.12.040
https://doi.org/10.1016/j.ejmech.2017.12.040
Autor:
Valéria Rêgo Alves Pereira, Marcos Veríssimo de Oliveira Cardoso, Andresa Pereira de Oliveira Mendes, Lucianna Rabelo Pessoa de Siqueira, Maria Carolina Accioly Brelaz de Castro, Ana Cristina Lima Leite, Paulo André Teixeira de Moraes Gomes, Milena Botelho Pereira Soares, Tanira Matutino Bastos, Edna de Farias Santiago, Arsênio Rodrigues Oliveira, Fábio André Brayner, Miria de Oliveira Barbosa, Diogo Rodrigo Magalhães Moreira
Publikováno v:
European Journal of Medicinal Chemistry. 111:46-57
Chagas disease is a parasitic infection caused by protozoan Trypanosoma cruzi that affects approximately 6-7 million people worldwide. Benznidazole is the only drug approved for treatment during the acute and asymptomatic chronic phases; however, its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08172faeb721db764e3dbf6dcf4f1db8
https://doi.org/10.1016/j.ejmech.2016.01.010
https://doi.org/10.1016/j.ejmech.2016.01.010
Autor:
Carlos André Laranjeira Miranda Filho, Sheilla Andrade de Oliveira, Jéssica Paula Lucena, Ignes Regina Dos Santos, Luiz Carlos Alves, Renata Lins Carneiro Leão, Veruska Cintia Alexandrino de Souza, Valéria Rêgo Alves Pereira, Fábio André Brayner dos Santos, Ana Cristina Lima Leite, Miria de Oliveira Barbosa, Roni Evencio de Araujo, Camila Juliet Barbosa Fernandes, Arsênio Rodrigues Oliveira, Edna de Farias Santiago
Publikováno v:
European Journal of Pharmaceutical Sciences. 146:105236
Schistosomicidal activity of six phthalimido-thiazoles derivatives with substitutions at the position three of the thiazole ring were analyzed in an experimental model. The substituents biphenyl (2i) and 2- naphthyl (2j) at a concentration of 80 µg/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d58945b8946f8e7a681aff01ede0a32
https://doi.org/10.1016/j.ejps.2020.105236
https://doi.org/10.1016/j.ejps.2020.105236
Autor:
Sheilla Andrade de Oliveira, Fábio André Brayner, Carlos André Laranjeira Miranda Filho, Mabilly Cox Holanda de Barros Dias, Arsênio Rodrigues Oliveira, Miria de Oliveira Barbosa, Jéssica Paula Lucena, Camila Juliet Barbosa Fernandes, Fabiano Amaro de Sousa, Ana Cristina Lima Leite, Luiz Carlos Alves
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 133
Schistosomiasis is a major public health problem worldwide, especially in poor communities. Praziquantel is currently the only drug available to treat schistosomiasis and it shows low efficacy against schistosomula and juveniles stages of Schistosoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16878a2cdb516c9e2435f98e67b59b65
https://pubmed.ncbi.nlm.nih.gov/30877068
https://pubmed.ncbi.nlm.nih.gov/30877068
Autor:
Suellen Melo Tibúrcio Cavalcanti, Elizabeth Fernanda de Oliveira Borba, Marcos Veríssimo de Oliveira Cardoso, Teresinha Gonçalves da Silva, Arsênio Rodrigues Oliveira, Gevanio Bezerra de Oliveira Filho, Ana Cristina Lima Leite, Paulo André Teixeira de Moraes Gomes, Lawrence J. Abraham, Belinda J. Kaskow, Lucas Cunha Duarte Coelho, Diogo Rodrigo Magalhães Moreira, Lucianna Rabelo Pessoa de Siqueira, Mahdad Karimi, Miria de Oliveira Barbosa
Publikováno v:
Med. Chem. Commun.. 5:758-765
Modulation of the immune system is an emerging concept in the control of tumor growth. Bearing in mind the pharmacological properties of thalidomide and its phthalimide derivatives, we describe here the structural design, synthesis and pharmacologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e6bb330897304ba8b791082bd3b3123
https://doi.org/10.1039/c4md00070f
https://doi.org/10.1039/c4md00070f
Autor:
Natáli Tereza Capistrano Costa, Rafaela Salgado Ferreira, Thiago André Ramos dos Santos, Edna de Farias Santiago, Marcos Veríssimo de Oliveira Cardoso, Ana Cristina Lima Leite, Marcelo Zaldini Hernandes, Glaécia Aparecida do Nascimento Pereira, Valéria Rêgo Alves Pereira, Aline Caroline da Silva, Diogo Rodrigo Magalhães Moreira, Fábio André Brayner dos Santosd, Paulo André Teixeira de Moraes Gomes, Miria de Oliveira Barbosa
Publikováno v:
European journal of medicinal chemistry. 121
In previous studies, the compound 3-(bromopropiophenone) thiosemicarbazone was described as a potent anti-Trypanosoma cruzi and cruzain inhibitor. In view to optimize this activity, 1,3-thiazole core was used as building-block strategy to access new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd8d6dce84a7e5471a281d7d7dcb64f
https://pubmed.ncbi.nlm.nih.gov/27295485
https://pubmed.ncbi.nlm.nih.gov/27295485