Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Mirhan N. Makled"'
Autor:
Ahmed B. Shehab El-Din, Mirhan N. Makled, Rania R. Abdelaziz, Nariman M. Gameil, Mohammed S. El-Awady, El-Sayed M. Ammar
Publikováno v:
Human & Experimental Toxicology. 40:S573-S582
Inflammation and oxidative stress are the major pathways involved in ischemia–reperfusion (I/R)-induced renal injury. This study was designed to evaluate the potential effect of pomegranate against I/R-induced renal injury. I/R injury was induced i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea8bda082fb9574abe483a265354a516
https://doi.org/10.1177/09603271211041998
https://doi.org/10.1177/09603271211041998
Autor:
Mirhan N. Makled, Ahmed R. El‐Sheakh
Publikováno v:
Journal of biochemical and molecular toxicologyREFERENCES.
The current study was designed to investigate the potential anti-inflammatory and antioxidant effects of fingolimod against Ovalbumin (Ova)-induced allergic airway inflammation compared to dexamethasone. Fingolimod was given (0.5 mg/kg/day, p.o.) for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e65380356445534c0bc7a3dad068ceb0
https://pubmed.ncbi.nlm.nih.gov/36468814
https://pubmed.ncbi.nlm.nih.gov/36468814
Publikováno v:
Environmental Science and Pollution Research. 29:5812-5826
There is increasing interest in the use of natural products to treat many diseases, considering the minimal toxicity, availability, and low cost. Propolis, a natural resinous product produced by honeybees, has been proven for its antioxidant and anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b136e94554a34f5a53bebfc032c0a9aa
https://doi.org/10.1007/s11356-021-16093-6
https://doi.org/10.1007/s11356-021-16093-6
Publikováno v:
Fundamental & Clinical Pharmacology. 35:940-954
Colon rectal cancer (CRC) is the second commonest malignancy in developed countries and a significant cause of mortality. Tenofovir reportedly reduces the risk of hepatocellular carcinoma and interferes with cell cycle and cell proliferation. The cur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c0ecd4c50f10992bc2ec56282f2939
https://doi.org/10.1111/fcp.12679
https://doi.org/10.1111/fcp.12679
Publikováno v:
Basicclinical pharmacologytoxicologyREFERENCES. 130(5)
Because of the approved immunomodulatory activities of fingolimod, the current study aimed at studying the curative potential of fingolimod against experimentally induced ulcerative colitis (UC) via modulating pro/anti-inflammatory cytokines release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d54f563a84f5814b3bc5ccb1770693
https://pubmed.ncbi.nlm.nih.gov/35274449
https://pubmed.ncbi.nlm.nih.gov/35274449
Autor:
Mirhan N. Makled, Eman Said
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 35
Cisplatin is a chemotherapeutic agent whose therapeutic use is greatly limited by the associated organs' toxicity and particularly, testicular toxicity. Cisplatin-induced testicular damage reported being mediated through mitochondria-mediated apoptos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df41ec1ee25193ded1ee620441400392
https://doi.org/10.1002/jbt.22817
https://doi.org/10.1002/jbt.22817
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 35
Liver fibrosis is a public health burden that is highly associated with morbidity and mortality. Therefore, this study aims to explore the anti-fibrotic effects of low dose of paclitaxel (PTX) against thioacetamide (TAA)-induced liver fibrosis in rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a474e7f689302d4866dfd4611201d003
https://doi.org/10.1002/jbt.22745
https://doi.org/10.1002/jbt.22745
Publikováno v:
Life sciences. 260
Aims Tobacco smoking is a major health problem associated with lung and liver damage. Lung and liver damage secondary to tobacco smoking is mediated through nicotine-induced oxidative stress. Therefore, we hypothesized that antioxidant treatment with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46009119a43c43c0d90b3ccef0bfe8f9
https://pubmed.ncbi.nlm.nih.gov/32937159
https://pubmed.ncbi.nlm.nih.gov/32937159
Publikováno v:
Physiol Res
Proper renal blood flow (RBF) and glomerular filtration rate (GFR) are critical for maintaining normal blood pressure, kidney function and water and electrolyte homeostasis. The renal microvasculature expresses a multitude of receptors mediating vaso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a3663578355caa222d616f1c97d5c5
https://europepmc.org/articles/PMC8006557/
https://europepmc.org/articles/PMC8006557/
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 392(12)
Liver fibrosis is a challenging global health problem resulting from chronic liver injury with no treatment currently available. It has been shown that activators for different peroxisome proliferator-activated receptor (PPAR) isoforms (α, γ, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de00463c8aff4b7dd5a8485077089ed
https://pubmed.ncbi.nlm.nih.gov/31367862
https://pubmed.ncbi.nlm.nih.gov/31367862