Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Mireya Paulina Velasquez"'
Autor:
Hong Mu-Mosley, Lauren Ostermann, Muharrem Muftuoglu, Abishek Vaidya, Challice L. Bonifant, Mireya Paulina Velasquez, Stephen Gottschalk, Michael Andreeff
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Immunotherapy with T-cells expressing bispecific T-cell engagers (ENG T-cells) is a promising approach to improve the outcomes for patients with recurrent/refractory acute myeloid leukemia (AML). However, similar to T-cells expressing chimeric antige
Externí odkaz:
https://doaj.org/article/cfa79794acd245c0bf70e6bce2d55079
Autor:
Janice M. Riberdy, Sheng Zhou, Fei Zheng, Young-In Kim, Jennifer Moore, Abishek Vaidya, Robert E. Throm, April Sykes, Natasha Sahr, Challice L. Bonifant, Byoung Ryu, Stephen Gottschalk, Mireya Paulina Velasquez
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 571-581 (2020)
Chimeric antigen receptor (CAR) T cells targeting CD123, an acute myeloid leukemia (AML) antigen, hold the promise of improving outcomes for patients with refractory/recurrent disease. We generated five lentiviral vectors encoding CD20, which may ser
Externí odkaz:
https://doaj.org/article/00f59d1265734c9e80eae423e4fa63df
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Chimeric antigen receptor (CAR) T-cell therapy combines antigen-specific properties of monoclonal antibodies with the lytic capacity of T cells. An effective and safe CAR-T cell therapy strategy relies on identifying an antigen that has high expressi
Externí odkaz:
https://doaj.org/article/bf7f740860484a71a617907389cbe23f
Autor:
Arpad Szoor, Abishek Vaidya, Mireya Paulina Velasquez, Zhuyong Mei, Daniel L. Galvan, David Torres, Adrian Gee, Andras Heczey, Stephen Gottschalk
Publikováno v:
Molecular Therapy: Oncolytics, Vol 6, Iss C, Pp 69-79 (2017)
The outcome for advanced stage hepatocellular carcinoma (HCC) remains poor, highlighting the need for novel therapies. Genetically modified mesenchymal stem cells (MSCs) are actively being explored as cancer therapeutics due to their inherent ability
Externí odkaz:
https://doaj.org/article/e7c3087b5a4d46068ecf53e0afe700b4
Publikováno v:
Children, Vol 7, Iss 2, p 14 (2020)
Outcomes for pediatric patients with acute myeloid leukemia (AML) remain poor, highlighting the need for improved targeted therapies. Building on the success of CD19-directed immune therapy for acute lymphocytic leukemia (ALL), efforts are ongoing to
Externí odkaz:
https://doaj.org/article/2d286a7577a14f92b0f78d22f6bb5f1d
Autor:
Stephen Gottschalk, Hao Liu, Meng-Fen Wu, Phuong Nguyen, Aarohi Thakkar, Abishek Vaidya, Arpad Szoor, Mireya Paulina Velasquez
S1: T-cell immunophenotyping by flow cytometry. S2: Determination of TSCM presence in PBMC and NT T-cells by flow cytometry. S3: CD19-ENGT-cells and CD19-ENGT-cells expressing CD80 and/or 41BBL kill Nalm 6 cells efficiently. S4: Experimental set up o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5593cebf15ada10ed5c86ec40e103c90
https://doi.org/10.1158/2326-6066.22538302.v1
https://doi.org/10.1158/2326-6066.22538302.v1
Autor:
Stephen Gottschalk, Hao Liu, Meng-Fen Wu, Phuong Nguyen, Aarohi Thakkar, Abishek Vaidya, Arpad Szoor, Mireya Paulina Velasquez
T cells expressing CD19-specific chimeric antigen receptors (CARs) with endodomains that encode a signaling domain derived from CD3ζ and CD28 or 41BB have potent antitumor activity in early-phase clinical studies for B-cell malignancies. Besides CD1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4dcd0597fb74e4403541a91a83b90c0
https://doi.org/10.1158/2326-6066.c.6548737.v1
https://doi.org/10.1158/2326-6066.c.6548737.v1
Autor:
Lauren Scherer, Candise Tat, Tim Sauer, Haruko Tashiro, Swati Naik, Mireya Paulina Velasquez, Stephen Gottschalk, Cliona M. Rooney, Malcolm K. Brenner, Bilal Omer
Publikováno v:
Blood. 140:7396-7397
Autor:
Swati Naik, Renee M. Madden, Amanda Lipsitt, Timothy Lockey, Jennyfer Bran, Jeffrey E. Rubnitz, Jeffery Klco, Barry Shulkin, Sagar L. Patil, Sarah Schell, Jeoungeun John Park, Janice Riberdy, Na Shang, Jaquelyn T. Zoine, Jennifer Wallace, Elaine Harstead, Catherine Willis, Jean-Yves Metais, Deanna M. Langfitt, Sheng Zhou, Salem M. Akel, Michael M. Meagher, Brandon M. Triplett, Stephen Gottschalk, Mireya Paulina Velasquez
Publikováno v:
Blood. 140:4584-4585
Autor:
Jaquelyn T. Zoine, Sarah E. Moore, Kalyan Immadisetty, Shams Akel, Deanna M Langfitt, Jorge Ibanez-Vega, Lindsay Talbot, Chris DeRenzo, Giedre Krenciute, M. Madan Babu, Mireya Paulina Velasquez
Publikováno v:
Blood. 140:4506-4507