Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mireya L. McKee"'
Autor:
Mireya L. McKee, Tom Brown, Phillip J. Milnes, Afaf H. El-Sagheer, Wenjing Meng, Benjamin G. Davis, Richard A. Muscat, Jonathan Bath, Rachel K. O'Reilly, Andrew J. Turberfield
Publikováno v:
Nature Chemistry. 8:542-548
Molecular machines that assemble polymers in a programmed sequence are fundamental to life. They are also an achievable goal of nanotechnology. Here, we report synthetic molecular machinery made from DNA which controls and records the formation of co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f3b1b517bc3f98b6e185257a4a53a28
https://doi.org/10.1038/nchem.2495
https://doi.org/10.1038/nchem.2495
Autor:
Wei M. Ho, Christoph M. Erben, Mireya L. McKee, Achillefs N. Kapanidis, Jonathan Malo, Andrew J. Turberfield, Russell P. Goodman
We present a facile method for linking recombinant proteins to DNA. It is based on the nickel-mediated interaction between a hexahistidine tag (His(6)-tag) and DNA functionalized with three nitrilotriacetic acid (NTA) groups. The resulting DNA-protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cbfffba9e39d7601cd58d6a740b7cd0
https://ora.ox.ac.uk/objects/uuid:bb15c938-7139-4196-81e3-70811478e1b4
https://ora.ox.ac.uk/objects/uuid:bb15c938-7139-4196-81e3-70811478e1b4
Autor:
Sean M. Kerwin, Mireya L. McKee
UK-1 is a bis(benzoxazole) natural product displaying activity against a wide range of human cancer cell lines. A simplified analog of UK-1, 4-carbomethoxy-2-(2'-hydroxyphenyl)benzoxazole, was previously found to be almost as active as UK-1 against c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c7a61bc3803edc3ad3b215fd999f9b1
https://ora.ox.ac.uk/objects/uuid:56293d42-6168-40ee-8fbf-7c11770f50d7
https://ora.ox.ac.uk/objects/uuid:56293d42-6168-40ee-8fbf-7c11770f50d7
Autor:
Jonathan Bath, Lijiang Song, Rachel K. O'Reilly, Mireya L. McKee, Andrew J. Turberfield, Eugen Stulz, Phillip J. Milnes
Publikováno v:
Chemical communications (Cambridge, England). 48(45)
Using a strand exchange mechanism we have prepared, by DNA templated chemistry, two 10-mers with defined and tunable monomer sequences. An optimized reaction protocol achieves 85% coupling yield per step, demonstrating that DNA-templated chemistry is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb9725d396d8c133b263270dd66ed913
http://ora.ox.ac.uk/objects/uuid:a0783ebd-ea90-445e-9679-a754a1998b84
http://ora.ox.ac.uk/objects/uuid:a0783ebd-ea90-445e-9679-a754a1998b84
Autor:
Andrew J. Turberfield, Mireya L. McKee, Jonathan Bath, Rachel K. O'Reilly, Phillip J. Milnes, Eugen Stulz
Publikováno v:
Journal of the American Chemical Society. 134(3)
A system for multistep DNA-templated synthesis is controlled by the sequential formation of DNA junctions. Reactants are attached to DNA adapters which are brought together by hybridization to DNA template strands. This process can be repeated to all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead9647785d6fdaeee7de64bb0314861
https://pubmed.ncbi.nlm.nih.gov/22276773
https://pubmed.ncbi.nlm.nih.gov/22276773
Autor:
Jonathan Bath, Rachel K. O'Reilly, Andrew J. Turberfield, Eugen Stulz, Phillip J. Milnes, Mireya L. McKee
Publikováno v:
Angewandte Chemie (International ed. in English). 49(43)
Biomimetic: A strand displacement mechanism was designed to permit DNA-templated synthesis of functional oligomers of arbitrary length (see scheme). Key features of the mechanism are that successive coupling reactions take place in near-identical env
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07df0dc9c5fba6e54521b635d54aba45
https://pubmed.ncbi.nlm.nih.gov/20836102
https://pubmed.ncbi.nlm.nih.gov/20836102
Autor:
Andrew J. Turberfield, Amanda C. Evans, Rachel K. O'Reilly, Mireya L. McKee, Eugen Stulz, Simon R. Gerrard
Publikováno v:
Organic & Biomolecular Chemistry. 9:1661
The efficiencies of DNA-templated acyl transfer reactions between a thioester modified oligonucleotide and a series of amine and thiol based nucleophiles are directly compared. The reactivity of the nucleophile, reaction conditions (solvent, buffer,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adefafe78e66cb1a2cc1c0c74eead325
https://doi.org/10.1039/c0ob00753f
https://doi.org/10.1039/c0ob00753f
Publikováno v:
Inorganic Chemistry. 21:85-88
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d090a4fe87ca6b0e9eeaeb804a793ab
https://doi.org/10.1021/ic00131a016
https://doi.org/10.1021/ic00131a016
Publikováno v:
Journal of the American Chemical Society. 101:5090-5092
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec17779b9469ffcc47862f0cbb552b1b
https://doi.org/10.1021/ja00511a062
https://doi.org/10.1021/ja00511a062