Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Mirella Ezban"'
Publikováno v:
Journal of Thrombosis and Haemostasis. 21:1493-1502
Publikováno v:
Journal of Thrombosis and Haemostasis. 21:480-487
Publikováno v:
Japanese Journal of Thrombosis and Hemostasis. 31:334-339
Publikováno v:
Haemophilia
Factor replacement therapy with factor VIII (FVIII) concentrates is the current standard of care for patients with haemophilia A. Postadministration monitoring of FVIII activity during on‐demand or prophylactic treatment is important, for example t
Publikováno v:
Acta Haematologica. 143:504-508
N8-GP (ESPEROCT®; turoctocog alfa pegol; Novo Nordisk A/S, Bagsvaerd, Denmark) is an extended half-life recombinant factor VIII (FVIII) molecule. FVIII-deficient plasma spiked with N8-GP can be accurately measured using many activated partial thromb
Publikováno v:
Haemophilia
Aim N8‐GP (turoctocog alfa pegol) is a glycoPEGylated, extended half‐life human recombinant factor VIII (FVIII) shown to be an efficacious treatment for patients with haemophilia A. Accurate monitoring of replacement therapy helps ensure proper d
Publikováno v:
Japanese Journal of Thrombosis and Hemostasis. 30:733-741
Publikováno v:
Haemophilia. 27
FVIII activity in samples taken at various time points from 21 patients treated with N8-GP (Esperoct® ; turoctocog alfa pegol) during the pathfinder clinical trial programme was assessed and compared using different assay methods. FVIII activity mea
Publikováno v:
Journal of Thrombosis and Haemostasis. 16:1817-1829
Essentials Factor VIIa binds activated platelets to promote hemostasis in hemophilia patients with inhibitors. The interactions and sites responsible for platelet-FVIIa binding are not fully understood. Endothelial cell protein C receptor (EPCR) is e
Autor:
Erika J. Martin, Melinda E Nolte, Bassem M. Mohammed, Marisa Ninivaggi, John C. Barrett, Emily K. Waters, Janice Kuhn, Donald F. Brophy, Mirella Ezban
Publikováno v:
Haemophilia. 24:815-822
INTRODUCTION The thrombin generation assay (TGA) can be used to monitor factor replacement therapy in patients with haemophilia. The TGA assay is typically performed using tissue factor as the reaction activator; however, activating with FIXa or FXIa