Výsledky vyhledávání - "Mirela Fekete"

Supplementary Figures S1-S2 from Dual Targeting of Phosphoinositide 3-Kinase and Mammalian Target of Rapamycin Using NVP-BEZ235 as a Novel Therapeutic Approach in Human Ovarian Carcinoma

Autor: Oliver Dorigo, Min Song, Hong Wu, Carol Eng, David Mulholland, Amer Karam, Kuang-Yui Michael Chen, Mirela Fekete, Gottfried E. Konecny, Chintda Santiskulvong

Supplementary Figures S1-S2.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000cf18c56536764481348459b42ca66
https://doi.org/10.1158/1078-0432.22442108.v1

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Data from Dual Targeting of Phosphoinositide 3-Kinase and Mammalian Target of Rapamycin Using NVP-BEZ235 as a Novel Therapeutic Approach in Human Ovarian Carcinoma

Autor: Oliver Dorigo, Min Song, Hong Wu, Carol Eng, David Mulholland, Amer Karam, Kuang-Yui Michael Chen, Mirela Fekete, Gottfried E. Konecny, Chintda Santiskulvong

Purpose: This study evaluates the effect of dual PI3K and mTOR inhibition using NVP-BEZ235 in preclinical models of ovarian cancer as a potential novel therapeutic strategy.Experimental Design: Inhibition of PI3K/Akt/mTOR signaling by NVP-BEZ235 was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::054110590ae9da05f5e64d717898dcd9
https://doi.org/10.1158/1078-0432.c.6518930.v1

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Effect of PI3K/Akt pathway inhibition-mediated G1 arrest on chemosensitization in ovarian cancer cells

Autor: Mirela, Fekete, Chintda, Santiskulvong, Carol, Eng, Oliver, Dorigo

Publikováno v: Anticancer research. 32(2)

Pharmacological inhibition of the phosphoinositide 3-kinase (PI3K)/Akt pathway prevents G(1) cell cycle progression into S, resulting in G(1) accumulation. The hypothesis that this arrest might negatively impact on chemotherapeutic agents primarily e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::38445909fd635ed416a92338428a556f
https://pubmed.ncbi.nlm.nih.gov/22287731

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Dual Targeting of Phosphoinositide 3-Kinase and Mammalian Target of Rapamycin Using NVP-BEZ235 as a Novel Therapeutic Approach in Human Ovarian Carcinoma

Autor: Chintda Santiskulvong, Oliver Dorigo, Gottfried E. Konecny, Kuang-Yui Michael Chen, Amer Karam, Hong Wu, Mirela Fekete, Carol Eng, David J. Mulholland, Min Song

Purpose: This study evaluates the effect of dual PI3K and mTOR inhibition using NVP-BEZ235 in preclinical models of ovarian cancer as a potential novel therapeutic strategy. Experimental Design: Inhibition of PI3K/Akt/mTOR signaling by NVP-BEZ235 was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e4aa79481f0e630bad20d9044c08651
https://europepmc.org/articles/PMC3078990/

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Cisplatin and PI3kinase inhibition decrease invasion and migration of human ovarian carcinoma cells and regulate matrix-metalloproteinase expression

Autor: Sara Zabih, Amer Karam, Oliver Dorigo, Mirela Fekete, Carol Eng, Chintda Santiskulvong

Publikováno v: Cytoskeleton.

Targeting of the PI3K (phosphoinositide3-kinase)/Akt/mTOR pathway in human ovarian cancer cells is a promising novel therapeutic strategy. We investigated the effects of cisplatin and the PI3K inhibitor LY294002 on invasion, migration and the express

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd850028d8017c5aaeff174d5b63f192
https://doi.org/10.1002/cm.20465

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