Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Mirela Ambeskovic"'
Autor:
Mirela Ambeskovic, Giselle Hopkins, Tanzi Hoover, Jeffrey T. Joseph, Tony Montina, Gerlinde A. S. Metz
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14769 (2023)
Pathological mechanisms contributing to Alzheimer’s disease (AD) are still elusive. Here, we identified the metabolic signatures of AD in human post-mortem brains. Using 1H NMR spectroscopy and an untargeted metabolomics approach, we identified (1)
Externí odkaz:
https://doaj.org/article/637f3d639f974535a7f91badba722241
Autor:
Jamshid Faraji, Mirela Ambeskovic, Nevyn Sauter, Jaxson Toly, Kera Whitten, Nayara Antunes Lopes, David M. Olson, Gerlinde A. S. Metz
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Important factors influencing the outcome of animal experiments in preclinical research are often overlooked. In the current study, the reaction of female and male rats toward the biological sex of a human experimenter was investigated in terms of an
Externí odkaz:
https://doaj.org/article/9fb1de8dba3946bfa45dc0474611d19e
Autor:
Nayara A. Lopes, Mirela Ambeskovic, Stephanie E. King, Jamshid Faraji, Nasrin Soltanpour, Erin A. Falkenberg, Taylor Scheidl, Mansi Patel, Xin Fang, Gerlinde A. S. Metz, David M. Olson
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3734 (2023)
Prenatal maternal stress is linked to adverse pregnancy and infant outcomes, including shortened gestation lengths, low birth weights, cardio-metabolic dysfunction, and cognitive and behavioural problems. Stress disrupts the homeostatic milieu of pre
Externí odkaz:
https://doaj.org/article/73a4230996be4345a3c74ec92ad00506
Autor:
Cheryl L. Currie, Jennifer L. Copeland, M. Lauren Voss, Lisa-Marie Swanepoel, Mirela Ambeskovic, Nimesh B. Patel, Erin K. Higa
Publikováno v:
BMC Public Health, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Tobacco use, alcohol use, and sugar-sweetened beverage consumption are each associated with increased cancer-risk. Psychological trauma is a common experience and a key driver of these behaviours among adults. The primary aim of t
Externí odkaz:
https://doaj.org/article/514f84c658f74efeafc9b1467cb8a4a2
Autor:
Jamshid Faraji, Nabiollah Soltanpour, Mirela Ambeskovic, Fabiola C. R. Zucchi, Pierre Beaumier, Igor Kovalchuk, Gerlinde A. S. Metz
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 11 (2017)
In a continuously stressful environment, the effects of recurrent prenatal stress (PS) may accumulate across generations and alter stress vulnerability and resilience. Here, we report in female rats that a family history of recurrent ancestral PS fac
Externí odkaz:
https://doaj.org/article/044c5ddf83774d5882ea8f7820325c01
Publikováno v:
Neuroscience and biobehavioral reviews. Elsevier Limited
Adverse early life experiences are major influences on developmental trajectories with potentially life-long consequences. Prenatal or early postnatal exposure to stress, undernutrition or environmental toxicants may reprogram brain development and i
Autor:
Gerlinde A. S. Metz, Douglas Kiss, Tony Montina, Yaroslav Ilnytskyy, Cheryl L. Currie, Mirela Ambeskovic, Igor Kovalchuk
Publikováno v:
Aging (Albany NY)
The incidence of non-communicable diseases (NCDs) is rising globally but their causes are generally not understood. Here we show that cumulative ancestral stress leads to premature aging and raises NCD risk in a rat population. This longitudinal stud
Autor:
Jamshid Faraji, Mirela Ambeskovic, Nevyn Sauter, Jaxson Toly, Kera Whitten, Nayara Antunes Lopes, David M. Olson, Gerlinde A. S. Metz
The sex of the experimenter may cause stress in animal models and be a major confounding factor in preclinical research. We studied the effects of the sex of the experimenter on female and male rat anxiety behaviours using thigmotaxis in the open fie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4ce346aebf5f6bd3b79781f9daf4eaa
https://doi.org/10.1101/2021.12.01.470834
https://doi.org/10.1101/2021.12.01.470834
Autor:
Mirela Ambeskovic, David P. Laplante, Thomas Kenney, Guillaume Elgbeili, Pierre Beaumier, Nagy Azat, Gabrielle Simcock, Sue Kildea, Suzanne King, Gerlinde A.S. Metz
Publikováno v:
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). 73
Exposure to adverse experiences during pregnancy, such as a natural disaster, can modify development of the child with potential long-term consequences. Elemental hair analysis may provide useful indicators of cellular homeostasis and child health. T
Autor:
M. Lauren Voss, Erin K. Higa, Mirela Ambeskovic, Nimesh B. Patel, Jennifer L. Copeland, Cheryl L. Currie, Lisa-Marie Swanepoel
Publikováno v:
BMC Public Health
BMC Public Health, Vol 19, Iss 1, Pp 1-11 (2019)
BMC Public Health, Vol 19, Iss 1, Pp 1-11 (2019)
Background Tobacco use, alcohol use, and sugar-sweetened beverage consumption are each associated with increased cancer-risk. Psychological trauma is a common experience and a key driver of these behaviours among adults. The primary aim of this study