Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Mirela, Hasu"'
Autor:
Justin W. Caravaggio, Yves L. Marcel, Mohamed Thabet, Ross W. Milne, Mirela Hasu, Stewart C. Whitman, John P. Veinot, Robin MacLaren, Joshua E. Raizman
Publikováno v:
Cardiovascular Pathology. 22:458-464
Background Insulin-degrading enzyme (IDE), a protease implicated in several chronic diseases, associates with the cytoplasmic domain of the macrophage Type A scavenger receptor (SR-A). Our goal was to investigate the effect of IDE deficiency (Ide−/
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 89:737-742
Innate immunity and, notably, Toll-like receptors (TLR), have an important role in atherogenesis. We have tested the hypothesis that the selective loss of TLR-2 by cells of bone marrow (BM) origin will protect low-density receptor-deficient (Ldlr −
Autor:
Lyne Sleiman, Mirela Hasu, Rob S. Beanlands, Mohamed Thabet, Stewart C. Whitman, Martin Holcik, Alex Norgaard, Yong-Xiang Chen
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Cellular inhibitor of apoptosis protein 2 (c IAP 2) is predicted to participate in atherosclerosis; however, its direct role in atherosclerosis development has not been investigated. We aimed to examine and assess the loss of c IAP 2 on at
Publikováno v:
The Canadian journal of cardiology. 28(2)
Background Caspase-1 is a cysteine protease that contributes to mammalian immunity through proteolytic activation of the proinflammatory cytokines, interleukin (IL)-1β and IL-18. Methods To determine if caspase-1 deficiency can protect apolipoprotei
Publikováno v:
Canadian journal of physiology and pharmacology. 89(10)
Innate immunity and, notably, Toll-like receptors (TLR), have an important role in atherogenesis. We have tested the hypothesis that the selective loss of TLR-2 by cells of bone marrow (BM) origin will protect low-density receptor-deficient (Ldlr (-/
Publikováno v:
Journal of Molecular and Cellular Cardiology. 24:989-1002
We investigated whether cardiomyocytes express specific albumin binding proteins (ABP) which may function in the dissociation of fatty acids from their non-covalent complexes with albumin. The experiments were performed on rat neonatal cardiomyocytes
Autor:
Nicolae Ghinea, Mirela Hasu, Maya Simionescu, Nicolae Simionescu, Felicia Antohe, Doina Popov, Ludy Dobrila
Publikováno v:
ACTA HISTOCHEMICA ET CYTOCHEMICA. 25:231-235
Confluent monolayers of cultured bovine aortic endothelial cells (BAEC) at 4°C bound specifically, saturably, and with high affinity radioiodinated bovine serum albumin ([125I] -BSA). Unlike bovine transferrin, fibrinogen, and immunoglobulin G, albu
Autor:
Leah, Rogers, Sarah, Burchat, Jessica, Gage, Mirela, Hasu, Mohamad, Thabet, Lindsay, Willcox, Lindsay, Wilcox, Tanya A, Ramsamy, Stewart C, Whitman
Publikováno v:
Cardiovascular Research
CD1d-restricted natural killer T (NKT) cells function by regulating numerous immune responses during innate and adaptive immunity. Depletion of all populations of CD1d-dependent NKT cells has been shown by several groups to reduce atherosclerosis in
Autor:
Mirela Hasu, Stewart C. Whitman, Rob S. Beanlands, T. Stephanie, Jennifer M. Renaud, Mohamed Thabet, L. Sleiman, Gary R. Small, R.A. deKemp, T. Dumochel, Jean N. DaSilva
Publikováno v:
Canadian Journal of Cardiology. 27:S238-S239
Publikováno v:
Acta diabetologica. 34(4)
Diabetic mice (6 weeks duration) were studied to assess the interaction of advanced glycation endproduct-modified albumin (AGE-Alb) with micro- and macrovascular endothelium, and to evaluate the alterations induced in the ultrastructure of the lung,