Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Mireille Dumoulin"'
Autor:
Reto Bader, Mireille Dumoulin
Publikováno v:
Protein & Peptide Letters. 13:211-212
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e9377b44202c79c88bf1101c573ce8c
https://doi.org/10.2174/092986606775338399
https://doi.org/10.2174/092986606775338399
Autor:
Elodie Duray, Margaux Lejeune, Frederic Baron, Yves Beguin, Nick Devoogdt, Ahmet Krasniqi, Yoline Lauwers, Yong Juan Zhao, Matthias D’Huyvetter, Mireille Dumoulin, Jo Caers
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-13 (2021)
Abstract Background Antibody-based therapies targeting CD38 are currently used as single agents as well as in combination regimens for multiple myeloma, a malignant plasma cell disorder. In this study, we aimed to develop anti-CD38 single-domain anti
Externí odkaz:
https://doaj.org/article/6b141013e0604fe3b0f374aa12371db3
Autor:
Jo Caers, Elodie Duray, Louise Vrancken, Guillaume Marcion, Valentina Bocuzzi, Kim De Veirman, Ahmet Krasniqi, Margaux Lejeune, Nadia Withofs, Nick Devoogdt, Mireille Dumoulin, Amelie Eriksson Karlström, Matthias D’Huyvetter
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Radioimmunotherapy (RIT) is a cancer treatment that combines radiation therapy with tumor-directed monoclonal antibodies (Abs). Although RIT had been introduced for the treatment of CD20 positive non-Hodgkin lymphoma decades ago, it never found a bro
Externí odkaz:
https://doaj.org/article/be1525215bad43ffa1f35ebe39a6b115
Autor:
Mónica Gómez-Benito, Noelia Granado, Patricia García-Sanz, Anne Michel, Mireille Dumoulin, Rosario Moratalla
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Alpha-synuclein (α-Syn) is a key protein involved in Parkinson's disease (PD) pathology. PD is characterized by the loss of dopaminergic neuronal cells in the substantia nigra pars compacta and the abnormal accumulation and aggregation of α-Syn in
Externí odkaz:
https://doaj.org/article/d5ab88ced7474a9a857c7a0a171b5364
Autor:
Frédéric Cawez, Paola Sandra Mercuri, Francisco Javier Morales-Yãnez, Rita Maalouf, Marylène Vandevenne, Frederic Kerff, Virginie Guérin, Jacques Mainil, Damien Thiry, Marc Saulmont, Alain Vanderplasschen, Pierre Lafaye, Gabriel Aymé, Pierre Bogaerts, Mireille Dumoulin, Moreno Galleni
Publikováno v:
Antimicrobial Agents and Chemotherapy. 67
Soluble single-domain fragments derived from the unique variable region of camelid heavy-chain antibodies (VHHs) against enzymes may behave as potent inhibitors. The immunization of alpacas with the CMY-2 β-lactamase led to the isolation of three VH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78eb671563e5e8352beb6f5aab5ff7c9
https://doi.org/10.1128/aac.01499-22
https://doi.org/10.1128/aac.01499-22
Autor:
Mireille Dumoulin
Publikováno v:
Biophysical Reviews. 12:13-18
I have been invited to summarize my career with an emphasis on the time I spent in the laboratory of Prof Christopher M. Dobson, who sadly passed away on September 8th 2019, and to describe his role as a mentor. I accepted this slightly unusual reque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db431aa0f8722cc6166124b0dd85b71
https://doi.org/10.1007/s12551-020-00612-9
https://doi.org/10.1007/s12551-020-00612-9
Publikováno v:
Protein Science, (2022)
Conjugation to polyethylene glycol (PEG) is a widely used approach to improve the therapeutic value of proteins essentially by prolonging their body residence time. PEGylation may however induce changes in the structure and/or the stability of protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde660f8a0ac817537863ebedd96d58a
https://hdl.handle.net/2078.1/264523
https://hdl.handle.net/2078.1/264523
Autor:
Yoline Lauwers, Yves Beguin, Mireille Dumoulin, Jo Caers, Margaux Lejeune, Frédéric Baron, Ahmet Krasniqi, Matthias D'Huyvetter, Yong Juan Zhao, Nick Devoogdt, Elodie Duray
Publikováno v:
Journal of Hematology & Oncology
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-13 (2021)
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-13 (2021)
Background Antibody-based therapies targeting CD38 are currently used as single agents as well as in combination regimens for multiple myeloma, a malignant plasma cell disorder. In this study, we aimed to develop anti-CD38 single-domain antibodies (s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04afc6e1c71e02279c98dd68f048a746
https://doi.org/10.1186/s13045-021-01171-6
https://doi.org/10.1186/s13045-021-01171-6
Publikováno v:
Advanced Functional Materials, p. 2101633 (2021)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e521d595ea230c562bf2edf5532ae9
https://hdl.handle.net/2078.1/248311
https://hdl.handle.net/2078.1/248311
Autor:
Cedrix J. Dongmo Foumthuim, Rita Grandori, Sara La Manna, Alessandra Corazza, Miguel A. Soler, Daniela Marasco, Giacinto Scoles, Cristina Cantarutti, Sara Fortuna, M Cristina Vargas, Mireille Dumoulin, Carlo Santambrogio
Herein, we compared the ability of linear and cyclic peptides generated in silico to target different protein sites: internal pockets and solvent-exposed sites. We selected human lysozyme (HuL) as a model target protein combined with the computationa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357730b784dcef91fe0ef1f7eb71ea33
https://hdl.handle.net/11368/2999240
https://hdl.handle.net/11368/2999240