Zobrazeno 1 - 10 of 62 pro vyhledávání: '"Mireille, VAN Gele"'
1
Akademický článek
A phase I/II trial of fixed-dose stereotactic body radiotherapy with sequential or concurrent pembrolizumab in metastatic urothelial carcinoma: evaluation of safety and clinical and immunologic response
Autor: Nora Sundahl, Katrien De Wolf, Sylvie Rottey, Karel Decaestecker, Daan De Maeseneer, Annabel Meireson, Els Goetghebeur, Valérie Fonteyne, Sofie Verbeke, Pieter De Visschere, Dries Reynders, Mireille Van Gele, Lieve Brochez, Piet Ost
Publikováno v: Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-9 (2017)
Abstract Background Current first-line standard of therapy for metastatic urothelial carcinoma is platinum-based combination chemotherapy. Pembrolizumab in phase III has demonstrated a promising overall response rate of 21.1% in patients with progres
Externí odkaz: https://doaj.org/article/3b897c191b3b4860aea23e21cb164730
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2
Akademický článek
Characterization data on the topical carrier DDC642
Autor: Eline Desmet, Stefanie Bracke, Katrien Forier, Lien Taevernier, Marc C.A. Stuart, Bart De Spiegeleer, Koen Raemdonck, Mireille Van Gele, Jo Lambert
Publikováno v: Data in Brief, Vol 7, Iss , Pp 1204-1210 (2016)
This article contains original data, figures and methods used in the characterization of the liposomal carrier ‘DDC642’ for topical applications, described in “An elastic liposomal formulation for RNAi-based topical treatment of skin disorders:
Externí odkaz: https://doaj.org/article/0015e7f4124748ceb4c0b06f2812e69e
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3
Akademický článek
JAK3 as an Emerging Target for Topical Treatment of Inflammatory Skin Diseases.
Autor: Ana Karina Alves de Medeiros, Reinhart Speeckaert, Eline Desmet, Mireille Van Gele, Sofie De Schepper, Jo Lambert
Publikováno v: PLoS ONE, Vol 11, Iss 10, p e0164080 (2016)
The recent interest and elucidation of the JAK/STAT signaling pathway created new targets for the treatment of inflammatory skin diseases (ISDs). JAK inhibitors in oral and topical formulations have shown beneficial results in psoriasis and alopecia
Externí odkaz: https://doaj.org/article/162c65ec23b14472b44796074549df9b
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4
Personalized development of antisense oligonucleotides for exon skipping restores type XVII collagen expression in junctional epidermolysis bullosa
Autor: Eline Desmet, Alfred Klausegger, Jo Lambert, Verena Wally, M. Wimmer, Mireille Van Gele, Michael Ablinger, Bernadette Liemberger, Els Van Maelsaeke, Ulrich Koller, Thomas Lettner, R. Zauner, Hannah Potocki, Theresa Palmetzhofer, Stefan Hainzl, Nicole Friedl, Julia Illmer, Johann W. Bauer, Manuela Reisenberger
Publikováno v: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
International Journal of Molecular Sciences, Vol 22, Iss 3326, p 3326 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 7
Intermediate junctional epidermolysis bullosa caused by mutations in the COL17A1 gene is characterized by the frequent development of blisters and erosions on the skin and mucous membranes. The rarity of the disease and the heterogeneity of the under
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5e453edbcdb554c66720b1f2143d9ad
https://biblio.ugent.be/publication/8758120/file/8758121
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5
Akademický článek
Characterization of Staphylococcus and Corynebacterium clusters in the human axillary region.
Autor: Chris Callewaert, Frederiek-Maarten Kerckhof, Michael S Granitsiotis, Mireille Van Gele, Tom Van de Wiele, Nico Boon
Publikováno v: PLoS ONE, Vol 8, Iss 8, p e70538 (2013)
The skin microbial community is regarded as essential for human health and well-being, but likewise plays an important role in the formation of body odor in, for instance, the axillae. Few molecular-based research was done on the axillary microbiome.
Externí odkaz: https://doaj.org/article/b284e4f5e42c4075954b04571dbca27c
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6
In vitro psoriasis models with focus on reconstructed skin models as promising tools in psoriasis research
Autor: Eline Desmet, Mireille Van Gele, Jo Lambert, Anesh Ramadhas
Publikováno v: Experimental Biology and Medicine. 242:1158-1169
Psoriasis is a complex chronic immune-mediated inflammatory cutaneous disease associated with the development of inflammatory plaques on the skin. Studies proved that the disease results from a deregulated interplay between skin keratinocytes, immune
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3408601c7a58e3eda1411f195555c2e2
https://doi.org/10.1177/1535370217710637
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7
A phase I/II trial of fixed-dose stereotactic body radiotherapy with sequential or concurrent pembrolizumab in metastatic urothelial carcinoma: evaluation of safety and clinical and immunologic response
Autor: Daan De Maeseneer, Pieter De Visschere, Sylvie Rottey, Els Goetghebeur, Karel Decaestecker, Piet Ost, Sofie Verbeke, Valérie Fonteyne, Dries Reynders, Nora Sundahl, Mireille Van Gele, Annabel Meireson, Katrien De Wolf, Lieve Brochez
Publikováno v: Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-9 (2017)
JOURNAL OF TRANSLATIONAL MEDICINE
Journal of Translational Medicine
Background Current first-line standard of therapy for metastatic urothelial carcinoma is platinum-based combination chemotherapy. Pembrolizumab in phase III has demonstrated a promising overall response rate of 21.1% in patients with progression or r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a15ba3b9b56745c0d6fdf69f586b11
http://link.springer.com/article/10.1186/s12967-017-1251-3
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8
Phase 1 Dose Escalation Trial of Ipilimumab and Stereotactic Body Radiation Therapy in Metastatic Melanoma
Autor: Piet Ost, Reinhart Speeckaert, Dries Reynders, Katrien De Wolf, Mireille Van Gele, Lieve Brochez, Vibeke Kruse, Annabel Meireson, Nora Sundahl, Benjamin Hennart, Els Goetghebeur
Publikováno v: International journal of radiation oncology, biology, physics. 100(4)
Purpose To report the results of a phase 1 trial evaluating the safety of the ipilimumab/radiation therapy combination in patients with metastatic melanoma. Patients and Methods Thirteen patients with metastatic melanoma were enrolled. Trial treatmen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2a2155fb4ae18e01371402f19f58033
https://pubmed.ncbi.nlm.nih.gov/29485070
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9
Towards the development of a RNAi-based topical treatment for psoriasis: Proof-of-concept in a 3D psoriasis skin model
Autor: Lynda Grine, Eline Desmet, Mireille Van Gele, Katrien Remaut, Jo Lambert
Publikováno v: Experimental dermatology. 27(5)
RNA interference has emerged as a powerful tool for therapeutic gene silencing, as it offers the possibility to silence virtually any known pathology-causing gene. However, in vivo delivery of RNAi molecules is hampered by their unfavourable physicoc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd617c84943e63d84613de3a94b183e
https://pubmed.ncbi.nlm.nih.gov/29431276
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10
Development of an oral mucosa model to study host-microbiome interactions during wound healing
Autor: Frederiek-Maarten Kerckhof, Pieter Van den Abbeele, Marc Bracke, Barbara Vanhoecke, Tom Van de Wiele, Charlotte Grootaert, Mireille Van Gele, Tine De Ryck, Joachim De Schrijver, Simon Swift, Laura Jaspaert
Publikováno v: Applied Microbiology and Biotechnology. 98:6831-6846
Crosstalk between the human host and its microbiota is reported to influence various diseases such as mucositis. Fundamental research in this area is however complicated by the time frame restrictions during which host-microbe interactions can be stu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba349da8d5498aec142df56c6608fcf
https://doi.org/10.1007/s00253-014-5841-1
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