Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Mireia Niso-Santano"'
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract The etiology of various neurodegenerative disorders that mainly affect the central nervous system including (but not limited to) Alzheimer’s disease, Parkinson’s disease and Huntington’s disease has classically been attributed to neuro
Externí odkaz:
https://doaj.org/article/0340e9507e65438ca80393877d5bae28
Autor:
Javier Ojalvo-Pacheco, Sokhna M. S. Yakhine-Diop, José M. Fuentes, Marta Paredes-Barquero, Mireia Niso-Santano
Publikováno v:
Biology, Vol 13, Iss 4, p 238 (2024)
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease caused by an expansion of the CAG trinucleotide repeat in exon 1 of the huntingtin (HTT) gene. This expansion leads to a polyglutamine (polyQ) tract at the N-terminal end
Externí odkaz:
https://doaj.org/article/48af2c48b8b84bc3844ba079439145bf
Autor:
Mercedes Blanco-Benítez, Ana Calderón-Fernández, Saray Canales-Cortés, Eva Alegre-Cortés, Elisabet Uribe-Carretero, Marta Paredes-Barquero, Alberto Gimenez-Bejarano, Gema Duque González, Patricia Gómez-Suaga, Juan Ortega-Vidal, Sofía Salido, Joaquín Altarejos, Guadalupe Martínez-Chacón, Mireia Niso-Santano, José M. Fuentes, Rosa A. González-Polo, Sokhna M. S. Yakhine-Diop
Publikováno v:
Molecular & Cellular Oncology, Vol 9, Iss 1 (2022)
Phenolic compounds derived from olive oil have beneficial health properties against cancer, neurodegenerative, and metabolic diseases. Therefore, there are discrepancies in their impact on mitochondrial function that result in changes in oxidative ca
Externí odkaz:
https://doaj.org/article/9687ece4146f48c7af61cb3d204be370
Publikováno v:
Journal of Functional Foods, Vol 94, Iss , Pp 105143- (2022)
Royal jelly (RJ) is one of the most valued natural products and is considered beneficial to human health, mainly due to its many biological and pharmacological properties. 10-Hydroxy-2-decenoic acid (10H2DA), also known as queen bee acid (QBA), is ex
Externí odkaz:
https://doaj.org/article/bbe94f09bb2b454588892d3a7fad439c
Autor:
Yaiza Corral Nieto, Sokhna M. S. Yakhine-Diop, Paula Moreno-Cruz, Laura Manrique García, Amanda Gabrielly Pereira, José A. Morales-García, Mireia Niso-Santano, Rosa A. González-Polo, Elisabet Uribe-Carretero, Sylvère Durand, Maria Chiara Maiuri, Marta Paredes-Barquero, Eva Alegre-Cortés, Saray Canales-Cortés, Adolfo López de Munain, Jordi Pérez-Tur, Ana Pérez-Castillo, Guido Kroemer, José M. Fuentes, José M. Bravo-San Pedro
Publikováno v:
Cells, Vol 12, Iss 5, p 806 (2023)
The identification of Parkinson’s disease (PD) biomarkers has become a main goal for the diagnosis of this neurodegenerative disorder. PD has not only been intrinsically related to neurological problems, but also to a series of alterations in perip
Externí odkaz:
https://doaj.org/article/917e21376071483687b2b7925531f170
Autor:
Eva Alegre-Cortés, Alberto Giménez-Bejarano, Elisabet Uribe-Carretero, Marta Paredes-Barquero, André R. A. Marques, Mafalda Lopes-da-Silva, Otília V. Vieira, Saray Canales-Cortés, Pedro J. Camello, Guadalupe Martínez-Chacón, Ana Aiastui, Roberto Fernández-Torrón, Adolfo López de Munain, Patricia Gomez-Suaga, Mireia Niso-Santano, Rosa A. González-Polo, José M. Fuentes, Sokhna M. S. Yakhine-Diop
Publikováno v:
Cells, Vol 11, Iss 19, p 3018 (2022)
Myotonic dystrophy type 1 (DM1) is an autosomal dominant disease caused by a CTG repeat expansion in the 3′ untranslated region of the dystrophia myotonica protein kinase gene. AKT dephosphorylation and autophagy are associated with DM1. Autophagy
Externí odkaz:
https://doaj.org/article/63ec18c48d0044c082b29aaa2f385fd7
Autor:
Elisabet Uribe-Carretero, Guadalupe Martinez-Chacón, Sokhna M. S. Yakhine-Diop, Gema Duque-González, Mario Rodríguez-Arribas, Eva Alegre-Cortés, Marta Paredes-Barquero, Saray Canales-Cortés, Elisa Pizarro-Estrella, Antonio Cuadrado, Rosa Ana González-Polo, José M. Fuentes, Mireia Niso-Santano
Publikováno v:
Antioxidants, Vol 11, Iss 7, p 1398 (2022)
KEAP1 is a cytoplasmic protein that functions as an adaptor for the Cullin-3-based ubiquitin E3 ligase system, which regulates the degradation of many proteins, including NFE2L2/NRF2 and p62/SQSTM1. Loss of KEAP1 leads to an accumulation of protein u
Externí odkaz:
https://doaj.org/article/c5c362062c1b42fbbd0a0832c1eaaf6f
Autor:
Jesus Alarcon-Gil, Ana Sierra-Magro, Jose A. Morales-Garcia, Marina Sanz-SanCristobal, Sandra Alonso-Gil, Marta Cortes-Canteli, Mireia Niso-Santano, Guadalupe Martínez-Chacón, Jose M. Fuentes, Angel Santos, Ana Perez-Castillo
Publikováno v:
Cells, Vol 11, Iss 15, p 2297 (2022)
Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease after Alzheimer’s disease. The principal pathological feature of PD is the progressive loss of dopaminergic neurons in the ventral midbrain. This pathology involves s
Externí odkaz:
https://doaj.org/article/bb317495902d454c98df5b75ab6736c7
Autor:
Eva Alegre-Cortés, Alicia Muriel-González, Saray Canales-Cortés, Elisabet Uribe-Carretero, Guadalupe Martínez-Chacón, Ana Aiastui, Adolfo López de Munain, Mireia Niso-Santano, Rosa A. Gonzalez-Polo, José M. Fuentes, Sokhna M. S. Yakhine-Diop
Publikováno v:
Antioxidants, Vol 9, Iss 6, p 524 (2020)
Parkinson’s disease (PD) is a neurodegenerative disorder that is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta. This neuronal loss, inherent to age, is related to exposure to environmental toxins and/or a g
Externí odkaz:
https://doaj.org/article/6e53fef3a6924a62ab14c3353d974cab
Autor:
Sokhna M. S. Yakhine-Diop, Mario Rodríguez-Arribas, Guadalupe Martínez-Chacón, Elisabet Uribe-Carretero, Rubén Gómez-Sánchez, Ana Aiastui, Adolfo López de Munain, José M. Bravo-San Pedro, Mireia Niso-Santano, Rosa A. González-Polo, José M. Fuentes
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Parkinson's disease (PD) is a multifactorial neurodegenerative disorder. The pathogenesis of this disease is associated with gene and environmental factors. Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most frequent genetic cause of fami
Externí odkaz:
https://doaj.org/article/9072bebe520e440198e2daff04c1bf4f