Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mireia Gómez Budia"'
Autor:
Henna Jäntti, Steffi Jonk, Mireia Gómez Budia, Sohvi Ohtonen, Ilkka Fagerlund, Mohammad Feroze Fazaludeen, Päivi Aakko-Saksa, Alice Pebay, Šárka Lehtonen, Jari Koistinaho, Katja M. Kanninen, Pasi I. Jalava, Tarja Malm, Paula Korhonen
Publikováno v:
Particle and Fibre Toxicology, Vol 21, Iss 1, Pp 1-21 (2024)
Abstract Background Air pollution is recognized as an emerging environmental risk factor for neurological diseases. Large-scale epidemiological studies associate traffic-related particulate matter (PM) with impaired cognitive functions and increased
Externí odkaz:
https://doaj.org/article/2ffcedbcf3f049898ce5fdfb9dd94b96
Autor:
Henna Jäntti, Valeriia Sitnikova, Yevheniia Ishchenko, Anastasia Shakirzyanova, Luca Giudice, Irene F. Ugidos, Mireia Gómez-Budia, Nea Korvenlaita, Sohvi Ohtonen, Irina Belaya, Feroze Fazaludeen, Nikita Mikhailov, Maria Gotkiewicz, Kirsi Ketola, Šárka Lehtonen, Jari Koistinaho, Katja M. Kanninen, Damian Hernández, Alice Pébay, Rosalba Giugno, Paula Korhonen, Rashid Giniatullin, Tarja Malm
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-22 (2022)
Abstract Background Microglia are the endogenous immune cells of the brain and act as sensors of pathology to maintain brain homeostasis and eliminate potential threats. In Alzheimer's disease (AD), toxic amyloid beta (Aβ) accumulates in the brain a
Externí odkaz:
https://doaj.org/article/1e1bbd5ec02d41988a4d4b166aeb1c91
Autor:
Nea Korvenlaita, Mireia Gómez‐Budia, Flavia Scoyni, Cristiana Pistono, Luca Giudice, Shaila Eamen, Sanna Loppi, Ana Hernández deSande, Benjamin Huremagic, Maria Bouvy‐Liivrand, Merja Heinäniemi, Minna U. Kaikkonen, Lesley Cheng, Andrew F. Hill, Katja M. Kanninen, Guido W. Jenster, Martin E. vanRoyen, Laura Ramiro, Joan Montaner, Tereza Batkova, Robert Mikulik, Rosalba Giugno, Jukka Jolkkonen, Paula Korhonen, Tarja Malm
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 1, Pp n/a-n/a (2023)
Abstract Hypoxia induces changes in the secretion of extracellular vesicles (EVs) in several non‐neuronal cells and pathological conditions. EVs are packed with biomolecules, such as microRNA(miR)‐21‐5p, which respond to hypoxia. However, the t
Externí odkaz:
https://doaj.org/article/094e282ac7ab43019b81d3777335442b
Autor:
Anssi Pelkonen, Cristiana Pistono, Pamela Klecki, Mireia Gómez-Budia, Antonios Dougalis, Henna Konttinen, Iveta Stanová, Ilkka Fagerlund, Ville Leinonen, Paula Korhonen, Tarja Malm
Publikováno v:
Cells, Vol 11, Iss 1, p 106 (2021)
Human pluripotent stem cell (hPSC)-derived neuron cultures have emerged as models of electrical activity in the human brain. Microelectrode arrays (MEAs) measure changes in the extracellular electric potential of cell cultures or tissues and enable t
Externí odkaz:
https://doaj.org/article/7de37164e56a4d1bb687d636042e7579
Autor:
Ilkka Fagerlund, Antonios Dougalis, Anastasia Shakirzyanova, Mireia Gómez-Budia, Anssi Pelkonen, Henna Konttinen, Sohvi Ohtonen, Mohammad Feroze Fazaludeen, Marja Koskuvi, Johanna Kuusisto, Damián Hernández, Alice Pebay, Jari Koistinaho, Tuomas Rauramaa, Šárka Lehtonen, Paula Korhonen, Tarja Malm
Publikováno v:
Cells, Vol 11, Iss 1, p 124 (2021)
Human cerebral organoids, derived from induced pluripotent stem cells, offer a unique in vitro research window to the development of the cerebral cortex. However, a key player in the developing brain, the microglia, do not natively emerge in cerebral
Externí odkaz:
https://doaj.org/article/51d43edc458d422caf349e2f8da0e316
Autor:
Elena Puris, Štěpán Kouřil, Lukáš Najdekr, Seppo Auriola, Sanna Loppi, Paula Korhonen, Mireia Gómez-Budia, Gert Fricker, Katja M. Kanninen, Tarja Malm, David Friedecký, Mikko Gynther
Publikováno v:
Neuroscience. 496:165-178
Neuroinflammation is an important feature in the pathogenesis and progression of central nervous system (CNS) diseases including Alzheimer's disease (AD). One of the widely used animal models of peripherally induced neuroinflammation and neurodegener
Autor:
Irene F. Ugidos, Cristiana Pistono, Paula Korhonen, Mireia Gómez-Budia, Valeriia Sitnikova, Pamela Klecki, Iveta Stanová, Jukka Jolkkonen, Tarja Malm
Publikováno v:
Stroke. 53(5)
Stroke is one of the leading causes of death worldwide and currently only few therapeutic options are available. Stroke is a sexually dimorphic disease contributing to the difficulty in finding efficient treatments. Poststroke neuroinflammation is ge
Autor:
Henna Konttinen, Valeria Sitnikova, Yevheniia Ishchenko, Anastasia Shakirzyanova, Luca Giudice, Irene F Ugidos, Mireia Gómez-Budia, Nea Korvenlaita, Sohvi Ohtonen, Irina Belaya, Feroze Fazaludeen, Nikita Mikhailov, Maria Gotkiewicz, Kirsi Ketola, Šárka Lehtonen, Jari Koistinaho, Katja M Kanninen, Damian Hernández, Alice Pébay, Rosalba Giugno, Paula Korhonen, Rashid Giniatullin, Tarja Malm
BackgroundMicroglia are the endogenous immune cells of the brain and act as sensors of pathology to maintain brain homeostasis and eliminate potential threats. In Alzheimer’s disease (AD), toxic amyloid beta (Aβ) accumulates in the brain and forms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5900f5eb8f6812162858261f7e8e5635
https://hdl.handle.net/11562/1080768
https://hdl.handle.net/11562/1080768
Autor:
Malm, Ilkka Fagerlund, Antonios Dougalis, Anastasia Shakirzyanova, Mireia Gómez-Budia, Anssi Pelkonen, Henna Konttinen, Sohvi Ohtonen, Mohammad Feroze Fazaludeen, Marja Koskuvi, Johanna Kuusisto, Damián Hernández, Alice Pebay, Jari Koistinaho, Tuomas Rauramaa, Šárka Lehtonen, Paula Korhonen, Tarja
Publikováno v:
Cells; Volume 11; Issue 1; Pages: 124
Human cerebral organoids, derived from induced pluripotent stem cells, offer a unique in vitro research window to the development of the cerebral cortex. However, a key player in the developing brain, the microglia, do not natively emerge in cerebral
Autor:
Mireia, Gómez-Budia, Henna, Konttinen, Liudmila, Saveleva, Paula, Korhonen, Pasi I, Jalava, Katja M, Kanninen, Tarja, Malm
Publikováno v:
Neurochemistry international. 136
Every second we inhale a danger in the air; many particles in the atmosphere can influence our lives. Outdoor air pollution, especially particulate matter is the largest environmental risk factor and has been associated with many cardiovascular and l