Inhibition of the Mitochondrial Glutamate Carrier SLC25A22 in Astrocytes Leads to Intracellular Glutamate Accumulation

Autor: Goubert, Emmanuelle, Mircheva, Yanina, Lasorsa, Francesco, Melon, Christophe, Profilo, Emanuela, Sutera, Julie, Becq, Hélène, Palmieri, Ferdinando, Palmieri, Luigi, Aniksztejn, Laurent, Molinari, Florence

Publikováno v: Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, 2017, 11, pp.149. ⟨10.3389/fncel.2017.00149⟩
Frontiers in Cellular Neuroscience, Frontiers, 2017, 11, pp.149. ⟨10.3389/fncel.2017.00149⟩

International audience; The solute carrier family 25 (SLC25) drives the import of a large diversity of metabolites into mitochondria, a key cellular structure involved in many metabolic functions. Mutations of the mitochondrial glutamate carrier SLC2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::51471d3c7d86745ab55c4a2ae8570604
https://hal.science/hal-01961870

Inhibition of the Mitochondrial Glutamate Carrier SLC25A22 in Astrocytes Leads to Intracellular Glutamate Accumulation.

Autor: Goubert E; INMED, INSERM, Aix-Marseille UniversitéMarseille, France., Mircheva Y; INMED, INSERM, Aix-Marseille UniversitéMarseille, France.; Centre De Recherche De L'Institut Universitaire En Santé Mentale de QuébecQuebec City, QC, Canada., Lasorsa FM; Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, and CNR Institute of Biomembranes, Bioenergetics and Molecular BiotechnologiesBari, Italy., Melon C; Aix-Marseille Université, CNRS, IBDM UMR 7288Marseille, France., Profilo E; Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, and CNR Institute of Biomembranes, Bioenergetics and Molecular BiotechnologiesBari, Italy., Sutera J; INMED, INSERM, Aix-Marseille UniversitéMarseille, France., Becq H; INMED, INSERM, Aix-Marseille UniversitéMarseille, France., Palmieri F; Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, and CNR Institute of Biomembranes, Bioenergetics and Molecular BiotechnologiesBari, Italy., Palmieri L; Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, and CNR Institute of Biomembranes, Bioenergetics and Molecular BiotechnologiesBari, Italy., Aniksztejn L; INMED, INSERM, Aix-Marseille UniversitéMarseille, France., Molinari F; INMED, INSERM, Aix-Marseille UniversitéMarseille, France.

Publikováno v: Frontiers in cellular neuroscience [Front Cell Neurosci] 2017 May 31; Vol. 11, pp. 149. Date of Electronic Publication: 2017 May 31 (Print Publication: 2017).