Zobrazeno 1 - 10
of 219
pro vyhledávání: '"Mircea Ivan"'
Autor:
Silpa Gampala, Fenil Shah, Xiaoyu Lu, Hye-ran Moon, Olivia Babb, Nikkitha Umesh Ganesh, George Sandusky, Emily Hulsey, Lee Armstrong, Amber L. Mosely, Bumsoo Han, Mircea Ivan, Jing-Ruey Joanna Yeh, Mark R. Kelley, Chi Zhang, Melissa L. Fishel
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-24 (2021)
Abstract Background Pancreatic cancer is a complex disease with a desmoplastic stroma, extreme hypoxia, and inherent resistance to therapy. Understanding the signaling and adaptive response of such an aggressive cancer is key to making advances in th
Externí odkaz:
https://doaj.org/article/751a9e3c189b45859ea1d97745ceb7f8
Autor:
Sampath Narayanan, Sofie Eliasson Angelstig, Cheng Xu, Jacob Grünler, Allan Zhao, Wan Zhu, Ning Xu Landén, Mona Ståhle, Jingping Zhang, Mircea Ivan, Raluca Georgiana Maltesen, Ileana Ruxandra Botusan, Neda Rajamand Ekberg, Xiaowei Zheng, Sergiu-Bogdan Catrina
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-11 (2020)
Narayanan et al. show that local administration of miR-210 accelerates wound healing specifically in diabetic mice. They find that miR-210 restores the metabolic balance in diabetic wounds by activating glycolysis and cellular migration. This study p
Externí odkaz:
https://doaj.org/article/80812abc7eff46a8a33277442fd73105
Autor:
Xue Wu, Cristina M. Niculite, Mihai Bogdan Preda, Annalisa Rossi, Toma Tebaldi, Elena Butoi, Mattie K. White, Oana M. Tudoran, Daniela N. Petrusca, Amber S. Jannasch, William P. Bone, Xingyue Zong, Fang Fang, Alexandrina Burlacu, Michelle T. Paulsen, Brad A. Hancock, George E. Sandusky, Sumegha Mitra, Melissa L. Fishel, Aaron Buechlein, Cristina Ivan, Spyros Oikonomopoulos, Myriam Gorospe, Amber Mosley, Milan Radovich, Utpal P. Davé, Jiannis Ragoussis, Kenneth P. Nephew, Bernard Mari, Alan McIntyre, Heiko Konig, Mats Ljungman, Diana L. Cousminer, Paolo Macchi, Mircea Ivan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Noncoding transcripts contribute to the adaptation of cellular processes to oxygen levels. Here the authors characterize a hypoxia responsive lncRNA lincNORS and show that it has a role in cellular sterol homeostasis.
Externí odkaz:
https://doaj.org/article/52284dde8b4044179316ad15dd802151
Autor:
Bradley A. Hancock, Yu-Hsiang Chen, Jeffrey P. Solzak, Mufti N. Ahmad, David C. Wedge, Dumitru Brinza, Charles Scafe, James Veitch, Rajesh Gottimukkala, Walt Short, Rutuja V. Atale, Mircea Ivan, Sunil S. Badve, Bryan P. Schneider, Xiongbin Lu, Kathy D. Miller, Milan Radovich
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-15 (2019)
Abstract Background Approximately two thirds of patients with localized triple-negative breast cancer (TNBC) harbor residual disease (RD) after neoadjuvant chemotherapy (NAC) and have a high risk-of-recurrence. Targeted therapeutic development for TN
Externí odkaz:
https://doaj.org/article/95c68e264d6a482f9c40b34a6e243f96
P38α/JNK signaling restrains erythropoiesis by suppressing Ezh2-mediated epigenetic silencing of Bim
Autor:
Ping Hu, Angel R. Nebreda, Helmut Hanenberg, Garrett H. Kinnebrew, Mircea Ivan, Mervin C. Yoder, Marie-Dominique Filippi, Hal E. Broxmeyer, Reuben Kapur
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Erythropoietin (EPO) stimulates erythropoiesis and is commonly used to treat anemia. Here Hu et al. find that P38α/JNK signaling restrains erythropoiesis independently of EPO by regulating epigenetic silencing of the proapoptotic protein Bim, and th
Externí odkaz:
https://doaj.org/article/83c7d281d7c544558201dc263cf809c2
Autor:
Rajesha Rupaimoole, Sherry Y. Wu, Sunila Pradeep, Cristina Ivan, Chad V. Pecot, Kshipra M. Gharpure, Archana S. Nagaraja, Guillermo N. Armaiz-Pena, Michael McGuire, Behrouz Zand, Heather J. Dalton, Justyna Filant, Justin Bottsford Miller, Chunhua Lu, Nouara C. Sadaoui, Lingegowda S. Mangala, Morgan Taylor, Twan van den Beucken, Elizabeth Koch, Cristian Rodriguez-Aguayo, Li Huang, Menashe Bar-Eli, Bradly G. Wouters, Milan Radovich, Mircea Ivan, George A. Calin, Wei Zhang, Gabriel Lopez-Berestein, Anil K. Sood
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-2 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/1ad9300d3cf4440c80b3af03df9e79a0
Autor:
Xue Wu, Cristina M. Niculite, Mihai Bogdan Preda, Annalisa Rossi, Toma Tebaldi, Elena Butoi, Mattie K. White, Oana M. Tudoran, Daniela N. Petrusca, Amber S. Jannasch, William P. Bone, Xingyue Zong, Fang Fang, Alexandrina Burlacu, Michelle T. Paulsen, Brad A. Hancock, George E. Sandusky, Sumegha Mitra, Melissa L. Fishel, Aaron Buechlein, Cristina Ivan, Spyros Oikonomopoulos, Myriam Gorospe, Amber Mosley, Milan Radovich, Utpal P. Davé, Jiannis Ragoussis, Kenneth P. Nephew, Bernard Mari, Alan McIntyre, Heiko Konig, Mats Ljungman, Diana L. Cousminer, Paolo Macchi, Mircea Ivan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/a1daa57c1a454e498c953cd0ba7dceb4
Autor:
Erica L. Clinkenbeard, Mark R. Hanudel, Keith R. Stayrook, Hitesh Nidumanda Appaiah, Emily G. Farrow, Taryn A. Cass, Lelia J. Summers, Colin S. Ip, Julia M. Hum, Joseph C. Thomas, Mircea Ivan, Briana M. Richine, Rebecca J. Chan, Thomas L. Clemens, Ernestina Schipani, Yves Sabbagh, Linlin Xu, Edward F. Srour, Marta B. Alvarez, Melissa A. Kacena, Isidro B. Salusky, Tomas Ganz, Elizabeta Nemeth, Kenneth E. White
Publikováno v:
Haematologica, Vol 102, Iss 11 (2017)
Externí odkaz:
https://doaj.org/article/2ff09e50f8954d7b85a3ed78797c1d49
Autor:
Lauren K Brady, Hejia Wang, Caleb M Radens, Yue Bi, Milan Radovich, Amit Maity, Cristina Ivan, Mircea Ivan, Yoseph Barash, Constantinos Koumenis
Publikováno v:
PLoS Biology, Vol 15, Iss 9, p e2002623 (2017)
Cells adjust to hypoxic stress within the tumor microenvironment by downregulating energy-consuming processes including translation. To delineate mechanisms of cellular adaptation to hypoxia, we performed RNA-Seq of normoxic and hypoxic head and neck
Externí odkaz:
https://doaj.org/article/7d5cefc4d03f454db2cedc98127d6412
Publikováno v:
International Journal of Mathematics and Mathematical Sciences, Vol 2005, Iss 23, Pp 3827-3833 (2005)
We study the approximation properties of beta operators of second kind. We obtain the rate of convergence of these operators for absolutely continuous functions having a derivative equivalent to a function of bounded variation.
Externí odkaz:
https://doaj.org/article/1d91a7991b7c4451bdc3dc3a46c8e6fc