Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Miratul MK Muqit"'
Autor:
Dipti Ranjan Lenka, Shakti Virendra Dahe, Odetta Antico, Pritiranjan Sahoo, Alan R Prescott, Miratul MK Muqit, Atul Kumar
Publikováno v:
eLife, Vol 13 (2024)
Loss-of-function Parkin mutations lead to early-onset of Parkinson’s disease. Parkin is an auto-inhibited ubiquitin E3 ligase activated by dual phosphorylation of its ubiquitin-like (Ubl) domain and ubiquitin by the PINK1 kinase. Herein, we demonst
Externí odkaz:
https://doaj.org/article/3f29e2a6e59d486a8abd2e720c70fea9
Autor:
Atul Kumar, Jevgenia Tamjar, Andrew D Waddell, Helen I Woodroof, Olawale G Raimi, Andrew M Shaw, Mark Peggie, Miratul MK Muqit, Daan MF van Aalten
Publikováno v:
eLife, Vol 6 (2017)
Mutations in the human kinase PINK1 (hPINK1) are associated with autosomal recessive early-onset Parkinson's disease (PD). hPINK1 activates Parkin E3 ligase activity, involving phosphorylation of ubiquitin and the Parkin ubiquitin-like (Ubl) domain v
Externí odkaz:
https://doaj.org/article/20fff1131a3e4ec08eaeefa1982c53ca
Autor:
Michael U Stevens, Nathalie Croteau, Mohamed A Eldeeb, Odetta Antico, Zhi Wei Zeng, Rachel Toth, Thomas M Durcan, Wolfdieter Springer, Edward A Fon, Miratul MK Muqit, Jean-François Trempe
Publikováno v:
Life Science Alliance. 6:e202201419
Autosomal recessive mutations in the Parkin gene cause Parkinson’s disease. Parkin encodes an ubiquitin E3 ligase that functions together with the kinase PINK1 in a mitochondrial quality control pathway. Parkin exists in an inactive conformation me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97bef42259c895b5077b144899ed2115
https://doi.org/10.26508/lsa.202201419
https://doi.org/10.26508/lsa.202201419
Publikováno v:
Current opinion in cell biology. 45
The Parkinson's disease (PD)-associated protein kinase, PTEN-induced putative kinase1 (PINK1), and ubiquitin E3 ligase Parkin, function in a common signalling pathway known to regulate mitochondrial network homeostasis and quality control, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::73adb11b03050c502be51e6211b7f128
https://pubmed.ncbi.nlm.nih.gov/28437683
https://pubmed.ncbi.nlm.nih.gov/28437683