WNT5B drives osteosarcoma stemness, chemoresistance and metastasis.

Autor: Perkins RS; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, Tennessee, USA.; Center for Cancer Research, University of Tennessee Health Science Center, Memphis, Tennessee, USA., Murray G; Department of Pathology, University of Tennessee Health Science Center, Memphis, Tennessee, USA.; Department of Pathology, Regional One Hospital, Memphis, Tennessee, USA., Suthon S; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, Tennessee, USA., Davis L; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, Tennessee, USA., Perkins NB 3rd; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, Tennessee, USA., Fletcher L; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, Tennessee, USA.; College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA., Bozzi A; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, Tennessee, USA., Schreiber SL; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, Tennessee, USA., Lin J; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, Tennessee, USA., Laxton S; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, Tennessee, USA.; College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA., Pillai RR; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, Tennessee, USA.; College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA., Wright AJ; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, Tennessee, USA.; College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA., Miranda-Carboni GA; Department of Pathology, University of Tennessee Health Science Center, Memphis, Tennessee, USA.; Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA., Krum SA; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, Tennessee, USA.; Center for Cancer Research, University of Tennessee Health Science Center, Memphis, Tennessee, USA.

Publikováno v: Clinical and translational medicine [Clin Transl Med] 2024 May; Vol. 14 (5), pp. e1670.

The role of WNT10B in physiology and disease: A 10-year update.

Autor: Perkins RS; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, TN, United States., Singh R; College of Medicine, University of Tennessee Health Science Center, Memphis, TN, United States., Abell AN; Department of Biological Sciences, University of Memphis, Memphis, TN, United States., Krum SA; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, TN, United States.; Center for Cancer Research, University of Tennessee Health Science Center, Memphis, TN, United States., Miranda-Carboni GA; Center for Cancer Research, University of Tennessee Health Science Center, Memphis, TN, United States.; Department of Medicine, Division of Hematology and Oncology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, United States.

Publikováno v: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2023 Feb 06; Vol. 11, pp. 1120365. Date of Electronic Publication: 2023 Feb 06 (Print Publication: 2023).

MAP3K4 promotes fetal and placental growth by controlling the receptor tyrosine kinases IGF1R/IR and Akt signaling pathway.

Autor: Perry CH; Department of Biological Sciences, University of Memphis, Memphis, Tennessee, USA., Mullins NA; Department of Biological Sciences, University of Memphis, Memphis, Tennessee, USA., Sweileh RBA; Department of Biological Sciences, University of Memphis, Memphis, Tennessee, USA., Shendy NAM; Department of Biological Sciences, University of Memphis, Memphis, Tennessee, USA; Division of Molecular Oncology, Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Roberto PA; Department of Biological Sciences, University of Memphis, Memphis, Tennessee, USA., Broadhurst AL; Department of Biological Sciences, University of Memphis, Memphis, Tennessee, USA., Nelson HA; Department of Biological Sciences, University of Memphis, Memphis, Tennessee, USA., Miranda-Carboni GA; University of Tennessee Health Science Center, Department of Medicine, Division of Hematology-Oncology, Center for Cancer Research, Memphis, Tennessee, USA., Abell AN; Department of Biological Sciences, University of Memphis, Memphis, Tennessee, USA. Electronic address: anabell@memphis.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2022 Sep; Vol. 298 (9), pp. 102310. Date of Electronic Publication: 2022 Jul 31.

Estrogen receptor alpha and NFATc1 bind to a bone mineral density-associated SNP to repress WNT5B in osteoblasts.

Autor: Suthon S; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, TN 38163, USA., Lin J; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, TN 38163, USA., Perkins RS; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, TN 38163, USA., Crockarell JR Jr; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, TN 38163, USA; Campbell Clinic, Memphis, TN 38126, USA., Miranda-Carboni GA; Department of Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA; Center for Cancer Research, University of Tennessee Health Science Center, Memphis, TN 38163, USA., Krum SA; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, TN 38163, USA; Center for Cancer Research, University of Tennessee Health Science Center, Memphis, TN 38163, USA. Electronic address: smirand5@uthsc.edu.

Publikováno v: American journal of human genetics [Am J Hum Genet] 2022 Jan 06; Vol. 109 (1), pp. 97-115. Date of Electronic Publication: 2021 Dec 13.

WNT5B in Physiology and Disease.

Autor: Suthon S; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, TN, United States., Perkins RS; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, TN, United States., Bryja V; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czechia.; Department of Cytokinetics, Institute of Biophysics, Czech Academy of Sciences, Brno, Czechia., Miranda-Carboni GA; Division of Hematology and Oncology, Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, United States.; Center for Cancer Research, University of Tennessee Health Science Center, Memphis, TN, United States., Krum SA; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, TN, United States.; Center for Cancer Research, University of Tennessee Health Science Center, Memphis, TN, United States.

Publikováno v: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2021 May 04; Vol. 9, pp. 667581. Date of Electronic Publication: 2021 May 04 (Print Publication: 2021).