Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Miranda Zoe Denham Smith"'
Publikováno v:
AIDS. 33:773-791
Despite the benefits of antiretroviral therapy (ART) for people living with HIV, there has been a long-standing research interest in interrupting ART as a strategy to minimize adverse effects of ART as well as to test interventions aiming to achieve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1036ba3a489e7d909932b831f702c993
https://doi.org/10.1097/qad.0000000000002113
https://doi.org/10.1097/qad.0000000000002113
Autor:
Brent Allan, Miranda Zoe Denham Smith, James H McMahon, Jennifer Power, Cipriano Martinez, Jillian S.Y. Lau, Sharon R Lewin
Publikováno v:
AIDS Research and Therapy
AIDS Research and Therapy, Vol 17, Iss 1, Pp 1-6 (2020)
AIDS Research and Therapy, Vol 17, Iss 1, Pp 1-6 (2020)
Background Analytical treatment interruptions (ATI) are commonly used clinical endpoints to assess interventions aimed at curing HIV or achieving antiretroviral therapy (ART)-free HIV remission. Understanding the acceptability of ATI amongst people l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b38f3039acbb034d9e9859cefa1fd715
http://europepmc.org/articles/PMC7653743
http://europepmc.org/articles/PMC7653743
Autor:
A. Toni Young, Jennifer Power, Jillian S.Y. Lau, Brent Allan, Miranda Zoe Denham Smith, Karine Dubé
Publikováno v:
Journal of Virus Eradication
Journal of Virus Eradication, Vol 6, Iss 4, Pp 100018-(2020)
Journal of Virus Eradication, Vol 6, Iss 4, Pp 100018-(2020)
Introduction Involving affected communities and people living with HIV (PLHIV) in HIV cure-focused clinical trials has ethical and practical benefits. However, there can be barriers to meaningful involvement of ‘lay people’ in scientific research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f758ff510fe8940e26e6d3dbb33c6fc3
https://pubmed.ncbi.nlm.nih.gov/33251026
https://pubmed.ncbi.nlm.nih.gov/33251026
Autor:
Jenny L. Anderson, Steven G. Deeks, Paul U. Cameron, Nicolas Chomont, Frederick Hecht, Wendy Hartogenesis, Peter Bacchetti, Gabriela Khoury, Rémi Fromentin, Sharon R Lewin, Miranda Zoe Denham Smith
Publikováno v:
AIDS (London, England), vol 30, iss 10
BACKGROUND HIV latent infection can be established in vitro by treating resting CD4 T cells with chemokines that bind to chemokine receptors (CKR), CCR7, CXCR3, and CCR6, highly expressed on T cells. OBJECTIVE To determine if CKR identify CD4 T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1ee8fcaf149124ffa783dc79083f13
https://escholarship.org/uc/item/6j29m84b
https://escholarship.org/uc/item/6j29m84b
Autor:
Erik Rollman, Damian F. J. Purcell, Andrew G. Brooks, Ian A. Ramshaw, Bartek Zuber, Stephen J. Kent, Miranda Zoe Denham Smith
Publikováno v:
The Journal of Immunology. 179:4571-4579
Both the magnitude and function of vaccine-induced HIV-specific CD8+ CTLs are likely to be important in the outcome of infection. We hypothesized that rapid cytolysis by CTLs may facilitate control of viral challenge. Release kinetics of the cytolyti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ac9345a9fbb9cbafcb84a4db314678
https://doi.org/10.4049/jimmunol.179.7.4571
https://doi.org/10.4049/jimmunol.179.7.4571
Publikováno v:
Current HIV/AIDS reports. 9(1)
Combination antiretroviral therapy (cART) has led to a reduction in morbidity and mortality in HIV-infected patients but therapy is lifelong and there is no cure for HIV. The major barriers to cure include HIV latency, which has been identified in di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878a2d69f54012de37075ebfe6bace2a
https://pubmed.ncbi.nlm.nih.gov/22249405
https://pubmed.ncbi.nlm.nih.gov/22249405
Autor:
Jeanette C. Reece, Caroline S. Fernandez, Anthony D. Kelleher, Sheilajen Alcantara, Miranda Zoe Denham Smith, Rosemarie D. Mason, Viv Peut, John Zaunders, Robert De Rose, Stephen J. Kent, Liyen Loh, Nabila Seddiki, Thakshila Amarasena
Publikováno v:
Journal of medical primatology. 37
Background Simple and effective delivery methods for cellular immunotherapies are needed. We recently published on the effectiveness of using ex vivo pulsing of overlapping SIV Gag 15mer peptides onto fresh peripheral blood cells in 32 SIVmac251-infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5476b0fe051c91755cc1dcc68d66074f
https://pubmed.ncbi.nlm.nih.gov/19187433
https://pubmed.ncbi.nlm.nih.gov/19187433
Autor:
Erik Rollman, Amanda J. Handley, Sheilajen Alcântara, Matthew Law, Rosemarie D. Mason, Miranda Zoe Denham Smith, C. Jane Batten, Vivienne Peut, Liyen Loh, Robert De Rose, Stephen J. Kent, Caroline S. Fernandez, Kim Wilson
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 4, Iss 5, p e1000055 (2008)
PLoS Pathogens, Vol 4, Iss 5, p e1000055 (2008)
Effective immunotherapies for HIV are needed. Drug therapies are life-long with significant toxicities. Dendritic-cell based immunotherapy approaches are promising but impractical for widespread use. A simple immunotherapy, reinfusing fresh autologou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8effb6608e46e2f7dbca46df7fa7747
https://pubmed.ncbi.nlm.nih.gov/18451982
https://pubmed.ncbi.nlm.nih.gov/18451982
Autor:
David Price, Stephen J. Kent, Tedi E. Asher, Daniel C. Douek, Vanessa Venturi, Miles P. Davenport, Miranda Zoe Denham Smith
T-cell receptors (TCRs) govern the specificity, efficacy, and cross-reactivity of CD8 T cells. Here, we studied CD8 T-cell clonotypes from Mane-A*10 + pigtail macaques responding to the simian immunodeficiency virus (SIV) Gag KP9 epitope in a setting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6577bb6510d4db52e5a8b94f11b7735a
Autor:
Erik Rollman, Robert De Rose, Stephen J. Kent, Caroline S. Fernandez, Jeanette C. Reece, C. Jane Batten, Vanessa Venturi, Miles P. Davenport, Miranda Zoe Denham Smith
Many current-generation human immunodeficiency virus (HIV) vaccines induce specific T cells to control acute viremia, but their utility following infection with escape mutant virus is unclear. We studied reversion to wild type of an escape mutant sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ecf2619f11e2f38a68de5e3c29c3021
https://europepmc.org/articles/PMC1866163/
https://europepmc.org/articles/PMC1866163/