Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Miranda W. de Jager"'
Autor:
Linette T. Oosting, Katka Franke, Michael V. Martin, Wigard P. Kloosterman, Jennifer A. Jamieson, Laura A. Glenn, Miranda W. de Jager, Jacoba van Zanten, Derk P. Allersma, Bahez Gareb
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1515 (2022)
Stage III–IV non-small cell lung cancer (NSCLC) is a devastating disease characterized by a poor prognosis. NSCLC tumors carry genetic mutations, which can lead to the expression of altered protein sequences. Peptides originating from mutated prote
Externí odkaz:
https://doaj.org/article/aa2c9d3be63c45099a8573226ec73064
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 12, Pp 2649-2656 (2005)
Lipid lamellae present in the outermost layer of the skin, the stratum corneum, form the main barrier for the diffusion of molecules through the skin. The presence of a unique 13 nm lamellar phase and its high crystallinity are characteristic for the
Externí odkaz:
https://doaj.org/article/d0c19711d98a438eaba2b547d1265534
Autor:
Miranda W. de Jager, Gert S. Gooris, Igor P. Dolbnya, Wim Bras, Maria Ponec, Joke A. Bouwstra
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 5, Pp 923-932 (2004)
Lipid lamellae present in the outermost layer of the skin protect the body from uncontrolled water loss. In human stratum corneum (SC), two crystalline lamellar phases are present, which contain mostly cholesterol, free fatty acids, and nine types of
Externí odkaz:
https://doaj.org/article/9d122bdd4d3746a9aa0c718a33395f5f
Autor:
Wouter Groenink, Gert S. Gooris, Co Janmaat, Joke A. Bouwstra, Joop A van der Spek, Maria Ponec, Miranda W. de Jager
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1758(5):636-644
The intercellular stratum corneum (SC) lipids form the main barrier for diffusion of substances through the skin. A porous substrate covered with synthetic SC lipids would be an attractive model to study percutaneous penetration, hereby replacing nat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c26dce9061b92a5690f0f2922f32c80
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1664:132-140
Cholesterol (CHOL), free fatty acids (FFA) and nine classes of ceramides (CER1-CER9) form the main constituents of the intercellular lipid lamellae in stratum corneum (SC), which regulate the skin barrier function. Both the presence of a unique 13-nm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca7aac2bfe6fe697fc6c5a3b3789cb8
https://doi.org/10.1016/j.bbamem.2004.05.001
https://doi.org/10.1016/j.bbamem.2004.05.001
Autor:
Igor P. Dolbnya, Miranda W. de Jager, Joke A. Bouwstra, Maria Ponec, Gert S. Gooris, Wim Bras
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 5, Pp 923-932 (2004)
Lipid lamellae present in the outermost layer of the skin protect the body from uncontrolled water loss. In human stratum corneum (SC), two crystalline lamellar phases are present, which contain mostly cholesterol, free fatty acids, and nine types of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::223c3d7c1185eab9ccd49bac7a4cea6f
http://www.sciencedirect.com/science/article/pii/S0022227520318332
http://www.sciencedirect.com/science/article/pii/S0022227520318332
Publikováno v:
Enhancement in Drug Delivery ISBN: 9780849332036
Enhancement in Drug Delivery
Enhancement in Drug Delivery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25782be154f293e1d3e89676eec67ee4
https://doi.org/10.1201/9781420004816.ch11
https://doi.org/10.1201/9781420004816.ch11
Publikováno v:
Journal of Investigative Dermatology, 123(5), 911-916
The lipid organization in the upper layer of the skin, the stratum corneum (SC), is important for the skin barrier function. This lipid organization, including the characteristic 13 nm lamellar phase, can be reproduced in vitro with mixtures based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3591b0cfa89fcec68db541a32ad9e6fc
https://hdl.handle.net/1887/3239401
https://hdl.handle.net/1887/3239401
Autor:
Wouter Groenink, Nadezhda Angelova, Elin Andersson, Miranda W. de Jager, Joke A. Bouwstra, Ruth Bielsa i Guivernau, Maria Ponec
Publikováno v:
Pharmaceutical research. 23(5)
The objective of this study was to evaluate the utility of a stratum corneum substitute (SCS) as a novel in vitro percutaneous penetration model. The SCS consists of synthetic stratum corneum (SC) lipids (cholesterol, free fatty acids, and specific c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d1ecf4aa72a7d8edf76ff034161ff0
https://pubmed.ncbi.nlm.nih.gov/16715385
https://pubmed.ncbi.nlm.nih.gov/16715385