Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Miranda Sun"'
Autor:
David J. Cutler, Yah Huei Wu-Chou, Eleanor Feingold, Nandita Mukhopadhyay, Elizabeth J. Leslie, George L. Wehby, Ingo Ruczinski, Jeffrey C. Murray, Samantha Ho, Philip Kuo-Ting Chen, Kimberly K. Diaz Perez, Claudia P. Restrepo Muñeton, Robert J. Lipinski, Madison R. Bishop, Frederic W.-B. Deleyiannis, Luz Consuelo Valencia-Ramirez, Pankaj Chopra, Mary L. Marazita, Harrison Brand, Terri H. Beaty, Seth M. Weinberg, Lina Moreno-Uribe, Jacqueline B. Hetmanski, Miranda Sun, Margaret A. Taub, Michael P. Epstein, Jacqueline T. Hecht
While de novo mutations (DNMs) are known to increase risk of congenital defects, DNMs have not been fully explored regarding orofacial clefts (OFCs), one of the most common human birth defects. Therefore, whole-genome sequencing of 756 case-parent tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fbcb19cbc0d12edc382ee7e050d8b7e
Autor:
David J. Cutler, Madison R. Bishop, Robert J. Lipinski, Jacqueline T. Hecht, Lina Moreno-Uribe, Margaret A. Taub, Elizabeth J. Leslie, Yah Huei Wu-Chou, Michael P. Epstein, Ingo Ruczinski, Jacqueline B. Hetmanski, Samantha Ho, Jeffrey C. Murray, Claudia P. Restrepo Muñeton, Nandita Mukhopadhyay, Luz Consuelo Valencia-Ramirez, Pankaj Chopra, Philip Kuo-Ting Chen, Kimberly K. Diaz Perez, Harrison Brand, Terri H. Beaty, Seth M. Weinberg, George L. Wehby, Eleanor Feingold, Mary L. Marazita, Frederic W.-B. Deleyiannis, Miranda Sun
Publikováno v:
Am J Hum Genet
Although de novo mutations (DNMs) are known to increase an individual's risk of congenital defects, DNMs have not been fully explored regarding orofacial clefts (OFCs), one of the most common human birth defects. Therefore, whole-genome sequencing of
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 55:779-791
Insulin-like growth factor (IGF)-1 is a potent mitogen of vascular smooth muscle cells (SMCs), but its role in pulmonary vascular remodeling associated with pulmonary hypertension (PH) is not clear. In an earlier study, we implicated IGF-1 in the pat
Publikováno v:
A97. STATION TO STATION: UNRAVELING THE MOLECULAR PATHOGENESIS OF PAH.
Publikováno v:
Vascular Pharmacology. 73:20-31
Pulmonary hypertension is a fatal disease characterized by a progressive increase in pulmonary artery pressure accompanied by pulmonary vascular remodeling and increased vasomotor tone. Although some biological pathways have been identified in neonat
Autor:
Qiwei Yang, Miranda Sun
Publikováno v:
Pediatrics and Neonatal Nursing - Open Journal. 1:1-5
ABBREVATIONS: ACh: Acetylcholine; ALK: Activin-like Kinase; BMP: Bone Morphogenetic Protein; BMPR2: BMP Receptor type II; BPD: Bronchopulmonary Dysplasia; cGMP: Cyclic Guanosine Monophosphate; ETA-R: Endothelin Receptor type A; ETB-R: Endothelin Rece
Autor:
Laura Bach, Ramaswamy Ramchandran, J. Usha Raj, Aarti Raghavan, David L. Geenen, Qiwei Yang, Miranda Sun
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 307:L537-L544
Pulmonary hypertension (PH) is a chronic disease characterized by a progressive increase in vasomotor tone, narrowing of the vasculature with structural remodeling, and increase in pulmonary vascular resistance. Current treatment strategies include n
Publikováno v:
Cell Proliferation. 46:654-664
Objective Pulmonary arterial hypertension, characterized by pulmonary vascular remodelling and vasoconstriction, is associated with excessive proliferative changes in pulmonary vascular walls. However, the role of HDACs in the phenotypic alteration o
Autor:
Miranda Sun, Guofei Zhou
Publikováno v:
Journal of Biomedical Science and Engineering. :1085-1089
Adenosine monophosphate-activated protein kinase (AMPK) is a heterotrimeric serine-threonine kinase important as a metabolic sensor for intracellular ATP levels and plays a key role in regulating cell survival and proliferation, particularly when cel
Publikováno v:
Journal of the American College of Cardiology. 69:2038
Purpose: MicroRNAs (miRNAs) are post-transcriptional gene regulators involved in a wide range of biological processes including angiogenesis. Bronchopulmonary dysplasia (BPD), also known as “arrested lung development”, is characterized by decreas