Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Miranda Shehu-Xhilaga"'
Publikováno v:
Drug Target Insights, Vol 2, Iss 1 (2007)
Abstract non disponibile
Externí odkaz:
https://doaj.org/article/ca47f423b9634a40a13ddc38495a922f
Publikováno v:
Drug Target Insights, Vol 2 (2007)
The targets for licensed drugs used for the treatment of human immunodeficiency virus type 1 (HIV-1) are confined to the viral reverse transcriptase (RT), protease (PR), and the gp41 transmembrane protein (TM). While currently approved drugs are effe
Externí odkaz:
https://doaj.org/article/6cebabad8d1045fca659363987c58ab3
Autor:
Miranda Shehu-Xhilaga
“There are liberties taken in rendering Albanian poetic nuance into English idiom; Ariadne's thread is often hard to follow. But poetry is there to show us a different dimension of our world, no matter if we lose ourselves there for a while. “By
Publikováno v:
Current Medicinal Chemistry. 12:1705-1719
During the past decade, combined highly active antiretroviral therapy (HAART) consisting of the nucleoside, non-nucleoside and protease inhibitors has improved the outlook for HIV-infected individuals. However, despite the clinical improvement associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c38e16f504461a69ff218d1700e1301
https://doi.org/10.2174/0929867054367211
https://doi.org/10.2174/0929867054367211
Publikováno v:
Nature Reviews Microbiology. 2:461-472
Many viruses carry more than one segment of nucleic acid into the virion particle, but retroviruses are the only known group of viruses that contain two identical (or nearly identical) copies of the RNA genome within the virion. These RNA genomes are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d76049cd34dc39c0420cf807d1d920
https://doi.org/10.1038/nrmicro903
https://doi.org/10.1038/nrmicro903
Autor:
Ronald C. Montelaro, Sherimay D. Ablan, Dimiter G. Demirov, Chaoping Chen, Eric O. Freed, Miranda Shehu-Xhilaga
Publikováno v:
Journal of Virology. 78:724-732
The Gag proteins of a number of different retroviruses contain late or L domains that promote the release of virions from the plasma membrane. Three types of L domains have been identified to date: Pro-Thr-Ala-Pro (PTAP), Pro-Pro-X-Tyr, and Tyr-Pro-A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e442f448b1d4812c2a92ca82c70323
https://doi.org/10.1128/jvi.78.2.724-732.2004
https://doi.org/10.1128/jvi.78.2.724-732.2004
Autor:
John Marshall, Miranda Shehu-Xhilaga, Melissa Hill, Johnson Mak, Suzanne M. Crowe, John C. Kappes
Publikováno v:
Journal of Virology. 76:4331-4340
The packaging of a mature dimeric RNA genome is an essential step in human immunodeficiency virus type 1 (HIV-1) replication. We have previously shown that overexpression of a protease (PR)-inactive HIV-1 Gag-Pro-Pol precursor protein generates nonin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31dfe5e90c862939c068459c0033aee0
https://doi.org/10.1128/jvi.76.9.4331-4340.2002
https://doi.org/10.1128/jvi.76.9.4331-4340.2002
Autor:
Miranda Shehu-Xhilaga, Suzanne M. Crowe, Shahan M. Campbell, J-Y Lee, John Marshall, Johnson Mak
Publikováno v:
Journal of Biomedical Science. 9:697-705
We have recently demonstrated that alteration of the human immunodeficiency virus type 1 (HIV-1) Gag/GagPol ratio in virus-producing cells reduces the infectivity of progeny viruses and hinders the formation of stable virion RNA dimers without impair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c352ab146d5bda14708646dafcb7ecd5
https://doi.org/10.1159/000067295
https://doi.org/10.1159/000067295
Autor:
Miranda Shehu-Xhilaga, Stephen Kent, Jane Batten, Ellis, Sarah L., Joel Daniel Van der Meulen, Moira O'Bryan, Paul Urquhart Cameron, Lewin, Sharon R., Mark Peter Hedger
Publikováno v:
Retrovirology, Vol 4, Iss 1, p 7 (2007)
Monash University
Retrovirology
Monash University
Retrovirology
Background Little is known about the progression and pathogenesis of HIV-1 infection within the male genital tract (MGT), particularly during the early stages of infection. Results To study HIV pathogenesis in the testis and epididymis, 12 juvenile m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9893bb5267e5c16a54e48e4f659a7d37
http://www.retrovirology.com/content/4/1/7
http://www.retrovirology.com/content/4/1/7
Autor:
Shahan M. Campbell, Johnson Mak, Miranda Shehu-Xhilaga, Suzanne M. Crowe, Pantelis Poumbourios, Melissa Hill
Human immunodeficiency virus type 1 (HIV-1) contains two copies of genomic RNA that are noncovalently linked via a palindrome sequence within the dimer initiation site (DIS) stem-loop. In contrast to the current paradigm that the DIS stem or stem-loo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03db5c4a15f66bd52f414685298f3aa0
https://europepmc.org/articles/PMC165254/
https://europepmc.org/articles/PMC165254/