Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Miranda Nebane"'
Autor:
Brandon J. Metge, Heba Allah M. Alsheikh, Sarah C. Kammerud, Dongquan Chen, Devika Das, N. Miranda Nebane, J. Robert Bostwick, Lalita A. Shevde, Rajeev S. Samant
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-14 (2024)
Abstract Metastatic dissemination from the primary tumor is a complex process that requires crosstalk between tumor cells and the surrounding milieu and involves the interplay between numerous cellular-signaling programs. Epithelial–mesenchymal tra
Externí odkaz:
https://doaj.org/article/fdb5e2dddfe24017af39bdd3f65354a8
Autor:
Lynn Rasmussen, Shalisa Sanders, Melinda Sosa, Sara McKellip, N. Miranda Nebane, Yohanka Martinez-Gzegozewska, Andrew Reece, Pedro Ruiz, Anna Manuvakhova, Ling Zhai, Brooke Warren, Aliyah Curry, Qinghua Zeng, J. Robert Bostwick, Paige N. Vinson
Publikováno v:
SLAS Discovery, Vol 29, Iss 5, Pp 100160- (2024)
Four years after the beginning of the COVID-19 pandemic, it is important to reflect on the events that have occurred during that time and the knowledge that has been gained. The response to the pandemic was rapid and highly resourced; it was also bui
Externí odkaz:
https://doaj.org/article/6dbac02830044c3ab9f63c4c7d35bd4c
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT Pseudomonas aeruginosa is an opportunistic pathogen that has been declared by the World Health Organization as a “priority 1 critical pathogen” needing immediate new strategies for chemotherapy. During infection, P. aeruginosa uses redun
Externí odkaz:
https://doaj.org/article/474c0b1586414d83b2ca683ec33d1003
Autor:
Gelare Ghajar-Rahimi, Amie M. Traylor, Bini Mathew, James R. Bostwick, N Miranda Nebane, Anna A. Zmijewska, Stephanie K. Esman, Saakshi Thukral, Ling Zhai, Vijaya Sambandam, Rita M. Cowell, Mark J. Suto, James F. George, Corinne E. Augelli-Szafran, Anupam Agarwal
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 1888 (2022)
Acute kidney injury (AKI) is a major public health concern with significant morbidity and mortality and no current treatments beyond supportive care and dialysis. Preclinical studies have suggested that heme-oxygenase-1 (HO-1), an enzyme that catalyz
Externí odkaz:
https://doaj.org/article/25f0f94d8f124a2fac06bb9aa63b0b1c
Autor:
Carolyn A. Robinson, Terri D. Lyddon, Hwi Min Gil, David T. Evans, Yury V. Kuzmichev, Jonathan Richard, Andrés Finzi, Sarah Welbourn, Lynn Rasmussen, N. Miranda Nebane, Vandana V. Gupta, Sam Ananthan, Zhaohui Cai, Elizabeth R. Wonderlich, Corinne E. Augelli-Szafran, Robert Bostwick, Roger G. Ptak, Susan M. Schader, Marc C. Johnson
Publikováno v:
Viruses, Vol 14, Iss 4, p 817 (2022)
HIV-1 Vpu targets the host cell proteins CD4 and BST-2/Tetherin for degradation, ultimately resulting in enhanced virus spread and host immune evasion. The discovery and characterization of small molecules that antagonize Vpu would further elucidate
Externí odkaz:
https://doaj.org/article/cb9aa0928f724cc5b71172c99af2a758
Autor:
Pery, Erez, Sheehy, Ann, Miranda Nebane, N., Misra, Vikas, Mankowski, Marie K., Rasmussen, Lynn, Lucile White, E., Ptak, Roger G., Gabuzda, Dana
Publikováno v:
In Virology October 2015 484:276-287
Autor:
Lori A. Emert-Sedlak, Omar Moukha-Chafiq, Haibin Shi, Shoucheng Du, John J. Alvarado, Vibha Pathak, Samuel G. Tanner, Robert N. Hunter, Miranda Nebane, Li Chen, Tatiana V. Ilina, Rieko Ishima, Sixue Zhang, Yury V. Kuzmichev, Elizabeth R. Wonderlich, Susan M. Schader, Corinne E. Augelli-Szafran, Roger G. Ptak, Thomas E. Smithgall
Publikováno v:
ACS Infect Dis
HIV-1 Nef is an attractive target for antiretroviral drug discovery because of its roles promoting HIV-1 infectivity, replication, and host immune system avoidance. Here we applied a screening strategy in which recombinant HIV-1 Nef protein was coupl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::064dd24ecf34062d1f6d9a8ee5a6334d
https://doi.org/10.1021/acsinfecdis.1c00288
https://doi.org/10.1021/acsinfecdis.1c00288
Autor:
N. Miranda Nebane, Yury V Kuzmichev, Elizabeth R. Wonderlich, Marc C. Johnson, Jonathan Richard, Susan M. Schader, Sarah Welbourn, Andrés Finzi, Corinne E. Augelli-Szafran, Vandana V. Gupta, Roger G. Ptak, Terri D. Lyddon, Carolyn A. Robinson, Robert Bostwick, Hwi Min Gil, Zhaohui Cai, Sam Ananthan, Lynn Rasmussen, David T. Evans
HIV-1 Vpu targets the host cell proteins CD4 and BST-2/Tetherin for degradation, ultimately resulting in enhanced virus spread and host immune evasion. The discovery and characterization of small molecules that antagonize Vpu would further elucidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09ea728eb1d665c2ecfc789c351c71ad
https://doi.org/10.1101/2021.07.30.454560
https://doi.org/10.1101/2021.07.30.454560
Autor:
Carlos C Goller, Mehreen Arshad, James W Noah, Subramaniam Ananthan, Carrie W Evans, N Miranda Nebane, Lynn Rasmussen, Melinda Sosa, Nichole A Tower, E Lucile White, Benjamin Neuenswander, Patrick Porubsky, Brooks E Maki, Steven A Rogers, Frank Schoenen, Patrick C Seed
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e96054 (2014)
Uropathogenic Escherichia coli (UPEC) is the leading cause of community-acquired urinary tract infections (UTIs), with over 100 million UTIs occurring annually throughout the world. Increasing antimicrobial resistance among UPEC limits ambulatory car
Externí odkaz:
https://doaj.org/article/87e084b83fca45db96122f19cf43b049
Autor:
Marie K. Mankowski, N. Miranda Nebane, Andrew Jay Brazier, Sara J. Buhrlage, Vikas Misra, Dana Gabuzda, Erez Pery, Roger G. Ptak, Lynn Rasmussen, Kottampatty S. Rajendran, Ann M. Sheehy, E. Lucile White
Publikováno v:
Journal of Biological Chemistry. 290:10504-10517
APOBEC3G (A3G) is a cellular cytidine deaminase that restricts HIV-1 replication by inducing G-to-A hypermutation in viral DNA and by deamination-independent mechanisms. HIV-1 Vif binds to A3G, resulting in its degradation via the 26 S proteasome. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db3565ad06467fd86deade1aa0992fb
https://doi.org/10.1074/jbc.m114.626903
https://doi.org/10.1074/jbc.m114.626903