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of 8
pro vyhledávání: '"Miranda N Hurst"'
Autor:
Elza Neelima Mathew, Miranda N Hurst, Baolin Wang, Vaibhav Murthy, Yuntao Zhang, Robert K DeLong
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243802 (2020)
Zinc oxide (ZnO) NP is considered as a nanoscale chemotherapeutic. Thus, the drug delivery of this inorganic NP is of considerable importance. Ras mutations are common in cancer and the activation of this signaling pathway is a hallmark in carcinoma,
Externí odkaz:
https://doaj.org/article/23f1b79ca75846a6b66de4cb52395977
Autor:
Yuntao Zhang, Robert K. Delong, Vaibhav Murthy, Miranda N Hurst, Baolin Wang, Elza Neelima Mathew
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243802 (2020)
PLoS ONE
PLoS ONE
Zinc oxide (ZnO) NP is considered as a nanoscale chemotherapeutic. Thus, the drug delivery of this inorganic NP is of considerable importance. Ras mutations are common in cancer and the activation of this signaling pathway is a hallmark in carcinoma,
Autor:
Meghana Ramani, Robert K. Delong, Jim E. Riviere, R. Tyler Morris, Miranda C. Mudge, Miranda N Hurst, Stanislaw A. Warcholek, Yuntao Zhang
Publikováno v:
Molecular Pharmaceutics. 14:614-625
There is current interest in harnessing the combined anticancer and immunological effect of nanoparticles (NPs) and RNA. Here, we evaluate the bioactivity of poly I:C (pIC) RNA, bound to anticancer zinc oxide NP (ZnO-NP) against melanoma. Direct RNA
Autor:
Velinda Vidaurre, Sua Myong, Jong-Chan Lee, Jaya Sarkar, Miranda N Hurst, Brian Guy, Charlotte M. Fare, Kevin Rhine, Hye Ran Koh, James Shorter, Xinyi Cai, Amirhossein Ghanbari Niaki, Lin Guo
Publikováno v:
Mol Cell
FUS is a nuclear RNA-binding protein and its cytoplasmic aggregation is a pathogenic signature of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD). It remains unknown how the FUS-RNA interactions contribute to phase separation, a
Autor:
Laurie L Washington, Spencer E. Thomas, Azure Risor-Marhanka, Garry Glaspell, Santosh Aryal, Robert K. Delong, Ashley Schaeffer, Richard C. Garrad, Adam K. Wanekaya, Miranda C. Mudge, Mohamed Abdelhakiem, Joshua J. Smith, R. Tyler Morris, Shanna Marroquin, Jennifer A Mitchell, Jeffrey Comer, Kartik Ghosh, Amber Lekey, Miranda N Hurst
Publikováno v:
Journal of biomedical nanotechnology. 13(2)
Biomedical applications for metal and metal oxide nanoparticles are rapidly increasing. Here their functional impact on two well-characterized model enzymes, Luciferase (Luc) or β-galactosidase (β-Gal) was quantitatively compared. Nickel oxide nano
Publikováno v:
Nanoscience and Nanotechnology Letters. 6:976-981
Autor:
Robert K. Delong, Miranda N Hurst
Publikováno v:
Scientific Reports
Two dimensional fluorescence difference spectroscopy (2D FDS) detects nanoparticle interactions following surface functionalization and biomolecule loading by generating a spectral signature of the fluorescent intensity per excitation and emission wa
Publikováno v:
Anticancer research. 36(5)
The effect of boron carbide (B4C) nanoparticles (NP) on protein-RNA complexes and metastatic phenotype of 3-D tumor spheroids was investigated.Characterization was performed by transmission electron microscopy (TEM), zeta potential (ZP), 2-dimensiona