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pro vyhledávání: '"Miranda Movahed"'
Epigenetic interaction between UTX and DNMT1 regulates diet-induced myogenic remodeling in brown fat
Autor:
Fenfen Li, Jia Jing, Miranda Movahed, Xin Cui, Qiang Cao, Rui Wu, Ziyue Chen, Liqing Yu, Yi Pan, Huidong Shi, Hang Shi, Bingzhong Xue
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
Brown adipocytes contribute to energy balance, and adipocyte development and brown adipocyte thermogenesis are in part regulated by epigenetic modifications. Here the authors report that the histone demethylase Utx maintains brown adipocyte identity
Externí odkaz:
https://doaj.org/article/9e1c665d859844b1bc78ae334cecc799
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 196 (2023)
2-naphthol is a low-molecular-weight (LMW) polycyclic aromatic hydrocarbon (PAH) and air pollutant associated with childhood obesity. There has been a recent emergence of studies on the consequences of PAHs on human health. Current epidemiological re
Externí odkaz:
https://doaj.org/article/404548c71a6149ebbb41e6b5b151d357
Epigenetic interaction between UTX and DNMT1 regulates diet-induced myogenic remodeling in brown fat
Autor:
Rui Wu, Hang Shi, Jia Jing, Yi Pan, Huidong Shi, Ziyue Chen, Qiang Cao, Liqing Yu, Bingzhong Xue, Fenfen Li, Miranda Movahed, Xin Cui
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
Nature Communications
Nature Communications
Brown adipocytes share the same developmental origin with skeletal muscle. Here we find that a brown adipocyte-to-myocyte remodeling also exists in mature brown adipocytes, and is induced by prolonged high fat diet (HFD) feeding, leading to brown fat