Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Miranda J. Smallwood"'
Publikováno v:
Antioxidants, Vol 13, Iss 3, p 269 (2024)
The addition of hydrogen peroxide (H2O2) to cultured cells is widely used as a method to modulate redox-regulated cellular pathways, including the induction of programmed cell death in cell culture experiments and the testing of pro- and antioxidant
Externí odkaz:
https://doaj.org/article/c8a0fb269d5e4231b237cb806c998897
Autor:
Alex S. Ferecskó, Miranda J. Smallwood, Adrian Moore, Corin Liddle, Jia Newcombe, Janet Holley, Jacqueline Whatmore, Nicholas J. Gutowski, Paul Eggleton
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1375 (2023)
Background: Some neurodegenerative diseases have an element of neuroinflammation that is triggered by viral nucleic acids, resulting in the generation of type I interferons. In the cGAS-STING pathway, microbial and host-derived DNA bind and activate
Externí odkaz:
https://doaj.org/article/bab224abafdd411e81d819454cea83de
Autor:
Mohammed Abu-Alghayth, Anni Vanhatalo, Lee J. Wylie, Sinead TJ. McDonagh, Christopher Thompson, Stefan Kadach, Paul Kerr, Miranda J. Smallwood, Andrew M. Jones, Paul G. Winyard
Publikováno v:
Redox Biology, Vol 43, Iss , Pp 101974- (2021)
Ingested inorganic nitrate (NO3⁻) has multiple effects in the human body including vasodilation, inhibition of platelet aggregation, and improved skeletal muscle function. The functional effects of oral NO3⁻ involve the in vivo reduction of NO3
Externí odkaz:
https://doaj.org/article/ccca76cc967d449a8f90645b4e0a2df6
Autor:
Luis B. Agellon, Xing-Zhen Chen, Joanna Jung, Paul Eggleton, Allison Kraus, Qin Wenying, Miranda J. Smallwood, Marek Michalak, Myriam Pujol, Jingfeng Tang, Douglas W. Zochodne, Janet E. Holley, Tautvydas Paskevicius, Jia Newcombe, Nick Gutowski, Alison Robinson
Publikováno v:
The FASEB Journal. 34:16662-16675
We previously showed that calnexin (Canx)-deficient mice are desensitized to experimental autoimmune encephalomyelitis (EAE) induction, a model that is frequently used to study inflammatory demyelinating diseases, due to increased resistance of the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b0516c602853b188a764fb029821f28
https://doi.org/10.1096/fj.202001539rr
https://doi.org/10.1096/fj.202001539rr
Autor:
J.K. Williams, Nigel Benjamin, Miranda J. Smallwood, R.J. D'Souza, Paul G. Winyard, Angela C. Shore, Mark Gilchrist
Publikováno v:
Nitric Oxide. 97:16-19
Background Nitric oxide (NO) is rapidly oxidised in humans to nitrite and nitrate, with nitrate being present in much greater abundance. These oxidation products can be recycled back into nitric oxide via a complex entero-salivary pathway, thus prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41fe3821721d5afdf044c2ba806ac14f
https://doi.org/10.1016/j.niox.2020.01.011
https://doi.org/10.1016/j.niox.2020.01.011
Autor:
Mario Siervo, Miranda J. Smallwood, Devi Mohan, Luigi Ferrucci, Andrea McGrattan, Stefania Bandinelli, Mark Gilchrist, Louise Robinson, Lauren C. Blekkenhorst, Blossom C. M. Stephan, Nicholas McMahon, Mohsen Mazidi, Oliver M. Shannon, Paul G. Winyard
Publikováno v:
International journal of food sciences and nutrition. 73(4)
Blood pressure (BP) control is a key target for interventions to reduce cognitive decline. This cross-sectional study explored associations between objective (24-hour urine excretion) and subjective (food frequency questionnaire [FFQ]) measures of di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b07fbd45038c8011f514beda2e9c59
https://pubmed.ncbi.nlm.nih.gov/34783276
https://pubmed.ncbi.nlm.nih.gov/34783276
Publikováno v:
Frontiers in Physiology, Vol 6 (2015)
Inorganic nitrate is present at high levels in beetroot and celery, and in green leafy vegetables such as spinach and lettuce. Though long believed inert, nitrate can be reduced to nitrite in the human mouth and, further, under hypoxia and/or low pH,
Externí odkaz:
https://doaj.org/article/72e3b4b1910047988f1e95f9c8a5d453
Autor:
Paul Kerr, Sinead T. J. McDonagh, Andrew M. Jones, Christopher Thompson, Mohammed Abu-Alghayth, Lee J. Wylie, Paul G. Winyard, Anni Vanhatalo, Stefan Kadach, Miranda J. Smallwood
Publikováno v:
Redox Biology, Vol 43, Iss, Pp 101974-(2021)
Redox Biology
Redox Biology
Ingested inorganic nitrate (NO3⁻) has multiple effects in the human body including vasodilation, inhibition of platelet aggregation, and improved skeletal muscle function. The functional effects of oral NO3⁻ involve the in vivo reduction of NO3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7fa45b9e4e94e527e85d09f1e56ac29
http://www.sciencedirect.com/science/article/pii/S2213231721001221
http://www.sciencedirect.com/science/article/pii/S2213231721001221
Autor:
Beatrice Knight, Angela C. Shore, Lidia Romanczuk, Paul G. Winyard, Amy Riddell, John Kirkwood, Mark Gilchrist, Miranda J. Smallwood
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-9 (2020)
BMC Nephrology
BMC Nephrology
Background Early identification and treatment of kidney transplant rejection episodes is vital to limit loss of function and prolong the life of the transplanted kidney and recipient. Current practice depends on detecting a creatinine rise. A biomark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7641c7b5ee98d6776aba7b1b8351c877
https://doi.org/10.1186/s12882-020-02096-x
https://doi.org/10.1186/s12882-020-02096-x