Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Miranda E, Sowder"'
Autor:
Deborah A. Lannigan, George A. O'Doherty, Jennifer A. Pietenpol, David R. Brenin, Miranda E. Sowder, Lejla Pasic, Zachary M. Sandusky, Yu Li, Mingzong Li, J. Preston Campbell, Katarzyna A. Ludwik
Metastatic breast cancer is an incurable disease and identification of novel therapeutic opportunities is vital. Triple-negative breast cancer (TNBC) frequently metastasizes and high levels of activated p90RSK (RSK), a downstream MEK-ERK1/2 effector,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1112720a72a8ecae1a317a315623e14
https://doi.org/10.1158/1535-7163.c.6538488.v1
https://doi.org/10.1158/1535-7163.c.6538488.v1
Autor:
Deborah A. Lannigan, George A. O'Doherty, Jennifer A. Pietenpol, David R. Brenin, Miranda E. Sowder, Lejla Pasic, Zachary M. Sandusky, Yu Li, Mingzong Li, J. Preston Campbell, Katarzyna A. Ludwik
Scratch assay using HDQ-P1 cells. Top vehicle, bottom (1b) (50 μM) over a 10h time frame.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe2f4a87b8e3cb08826060d505d988c
https://doi.org/10.1158/1535-7163.22506756.v1
https://doi.org/10.1158/1535-7163.22506756.v1
Autor:
Deborah A. Lannigan, George A. O'Doherty, Jennifer A. Pietenpol, David R. Brenin, Miranda E. Sowder, Lejla Pasic, Zachary M. Sandusky, Yu Li, Mingzong Li, J. Preston Campbell, Katarzyna A. Ludwik
Supplementary Materials and Methods; Table S1 and Figures S1 through S5; Supplementary Movies S1 through S3 Legends - Supplementary Materials and Methods: Description of velocity determination, conditions for immunostaining and sources and applicatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5c0ea993aa1da9ce24a7474708a263
https://doi.org/10.1158/1535-7163.22506765
https://doi.org/10.1158/1535-7163.22506765
Autor:
Miranda E Sowder, Rachelle W Johnson
Publikováno v:
JBMR Plus, Vol 3, Iss 3, Pp n/a-n/a (2019)
ABSTRACT Bone marrow provides a unique microenvironment favoring the colonization and outgrowth of metastatic tumor cells. Despite the high incidence of bone metastasis in breast and prostate cancer patients, many of the molecular mechanisms controll
Externí odkaz:
https://doaj.org/article/d8d48a6f8f4d4981bebc7d8f771c066b
Publikováno v:
Current Osteoporosis Reports. 15:231-238
This review highlights our current knowledge of oxygen tensions in the bone marrow, and how low oxygen tensions (hypoxia) regulate tumor metastasis to and colonization of the bone marrow. The bone marrow is a relatively hypoxic microenvironment, but
Autor:
Zachary M. Sandusky, Jennifer A. Pietenpol, Deborah A. Lannigan, J. Preston Campbell, David R. Brenin, Katarzyna A. Ludwik, Mingzong Li, Yu Li, George A. O'Doherty, Lejla Pasic, Miranda E. Sowder
Publikováno v:
Molecular Cancer Therapeutics. 15:2598-2608
Metastatic breast cancer is an incurable disease and identification of novel therapeutic opportunities is vital. Triple-negative breast cancer (TNBC) frequently metastasizes and high levels of activated p90RSK (RSK), a downstream MEK-ERK1/2 effector,
Autor:
Miranda E, Sowder, Rachelle W, Johnson
Publikováno v:
JBMR plus. 3(3)
Bone marrow provides a unique microenvironment favoring the colonization and outgrowth of metastatic tumor cells. Despite the high incidence of bone metastasis in breast and prostate cancer patients, many of the molecular mechanisms controlling metas
Autor:
Rachelle W. Johnson, Miranda E. Sowder
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Breast cancer cells frequently home to the bone, but the mechanisms controlling tumor colonization of the bone marrow remain unclear. We report significant enrichment of bone-disseminated estrogen receptor positive human MCF7 cells by 17 β-estradiol
Autor:
Rachelle W. Johnson, Miranda E. Sowder
Publikováno v:
JBMR Plus. 3:e10126
Bone marrow provides a unique microenvironment favoring the colonization and outgrowth of metastatic tumor cells. Despite the high incidence of bone metastasis in breast and prostate cancer patients, many of the molecular mechanisms controlling metas