Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Miranda Burnette"'
Autor:
James W. Clancy, Erin N. Howe, Siyuan Zhang, Jeremiah J. Zartman, Victoria Hendrick, Melanie E. Justice, Ian H. Guldner, Jun Li, Alicia T. Lamere, Patricia M. Schnepp, Uma K. Aryal, Crislyn D'Souza-Schorey, Miranda Burnette
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
Breast cancer brain metastases (BCBM) have a 5-20 year latency and account for 30% of mortality; however, mechanisms governing adaptation to the brain microenvironment remain poorly defined. We combine time-course RNA-sequencing of BCBM development w
Publikováno v:
Wound Repair and Regeneration
Angiogenesis is essential for the successful repair of tissues; however, in many chronic conditions, angiogenesis is inhibited. Placental tissues have been shown to illicit an angiogenic response both in vitro and in vivo, and the angiogenic properti
Autor:
Miranda Burnette, Mayland Chang, Kevin X. Rodriguez, Erin N. Howe, Patricia M. Schnepp, Jennifer L. Meloche, Jayda E. Meisel, Emily P. Bacher, Jeremiah J. Zartman, Xuejuan Tan, Brandon L. Ashfeld, Siyuan Zhang
Publikováno v:
ChemMedChem
With evolutionary drug resistance impacting efforts to treat disease, the need for small molecules that exhibit novel molecular mechanisms of action is paramount. In this study, we combined scaffold-directed synthesis with a hybrid experimental and t
Autor:
Sarah Burris, Miranda Burnette, Jeremiah J. Zartman, Eun-Kyoung Breuer, Saverio Gentile, Vidhya R. Rao, Simon Kaja, Daniela Fukushiro-Lopes, Debra Wyatt, Andrew T. Baker, Clodia Osipo, Dimitrios E. Kouzoukas, W. Keith Jones, Alexandra D. Hegel
Publikováno v:
Oncotarget
Potassium ion (K+) channels have been recently found to play a critical role in cancer biology. Despite that pharmacologic manipulation of ion channels is recognized as an important therapeutic approach, very little is known about the effects of targ
Autor:
Jeremiah J. Zartman, Simon Kaja, Saverio Gentile, Miranda Burnette, Claire M. Wells, Michael I. Nishimura, Glen L. Niebur, Ricardo Romero-Moreno, Eun Kyoung Breuer, Loredana Campo, Daniela Fukushiro-Lopes, Kimberly J. Curtis, Laurie E. Littlepage, Kent Hoskins, Annika Dalheim
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 3, Pp 1-15 (2019)
Cell Death and Disease, Vol 10, Iss 3, Pp 1-15 (2019)
Potassium ion channels are critical in the regulation of cell motility. The acquisition of cell motility is an essential parameter of cancer metastasis. However, the role of K+ channels in cancer metastasis has been poorly studied. High expression of
Autor:
Jeremiah J. Zartman, Miranda Burnette
Publikováno v:
Amino Acids. 47:2665-2670
While several studies have implicated polyamines (PAs) in development, little research has been done in genetically tractable model systems like Drosophila. Here, we integrate transcriptional and metabolic data across Drosophila development, and are
Publikováno v:
Mol. BioSyst.. 10:2713-2723
Drosophila cell culture is used as a model system with multiple applications including the identification of new therapeutic targets in screens, the study of conserved signal transduction pathway mechanisms, and as an expression system for recombinan
Autor:
Siyuan Zhang, Mayland Chang, Emily P. Bacher, Jennifer L. Meloche, Xuejuan Tan, Kevin X. Rodriguez, Jayda E. Meisel, Brandon L. Ashfeld, Miranda Burnette, Patricia M. Schnepp, Erin N. Howe, Jeremiah J. Zartman
Publikováno v:
ChemMedChem. 14:1618-1618